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RIFM fragrance ingredient safety assessment, p-tolyl acetate, CAS Registry Number 140-39-6

The existing information supports the use of this material as described in this safety assessment. p-Tolyl acetate was evaluated for genotoxicity, repeated dose toxicity, reproductive toxicity, local respiratory toxicity, phototoxicity/photoallergenicity, skin sensitization, and environmental safety. Data from read-across analog ethyl p-tolyl carbonate (CAS # 22719-81-9) show that p-tolyl acetate

RIFM fragrance ingredient safety assessment, isobutyl alcohol, CAS Registry Number 78-83-1

The existing information supports the use of this material as described in this safety assessment. Isobutyl alcohol was evaluated for genotoxicity, repeated dose toxicity, reproductive toxicity, local respiratory toxicity, phototoxicity/photoallergenicity, skin sensitization, and environmental safety. Data show that isobutyl alcohol is not genotoxic. Data on isobutyl alcohol provide a calculated M

Mate quality affects offspring sex ratio in blue tits

Questions concerning the occurrence of adaptive sex ratio manipulation have a long research tradition in evolutionary biology, but evidence from birds is scarce. It has been suggested that birds are unable to adaptively determine the sex of their young because of the constraints of their sex determination systems. Here we report results from a study of variation in offspring sex ratio in the blue

Development of semantic verbal fluency and narrative ability during summer vacation versus formal schooling

The detrimental effect of a lengthy summer vacation on important scholastic abilities such as reading, writing and mathematical skills is relatively well documented, but how language skills are affected by summer vacation is less investigated. The purpose of our study is to investigate how lexical organization and retrieval assessed by a semantic verbal fluency (SVF) task and oral narrative abilit

Acute spinal trauma

Injuries to the spinal column and spinal cord are a major cause of disability, affecting predominately young, healthy individuals. The majority of the spinal injuries (60%) affect young healthy males between 15 and 35 years of age, with important socioeconomic consequences, and the costs of lifetime care and rehabilitation are extremely high. As the longevity of the general population increases, t

Population Control and Sex-Selective Abortion in China and India : A Feminist Critique of Criminalisation

This chapter outlines some of the key concerns with criminalising sex-selective abortion (SSA) in China and India, highlighting that it offers no identifiable options for sustainable, women-centred, progressive change. Instead, the criminalisation of SSA sits firmly within other forms of carceral feminism. Framing SSA as “female foeticide,” “femicide,” or “gendercide” is problematic, as such terms

The mass distribution and gravitational potential of the Milky Way

We present mass models of the Milky Way created to fit observational constraints and to be consistent with expectations from theoretical modelling. The method used to create these models is that demonstrated in our previous study, and we improve on those models by adding gas discs to the potential, considering the effects of allowing the inner slope of the halo density profile to vary, and includi

Cytomegalovirus glycoprotein B-specific antibody analysis using electrochemiluminescence detection-based techniques

An electrochemiluminescence technique was used to develop versatile and sensitive assay strategies for determination of seroreactivities against biologically important cytomegalovirus neutralization epitopes expressed on glycoprotein B. Indirect binding assays showed wide linear assay ranges and revealed that serum samples diluted in parallel with a monoclonal antibody-based standard, simplifying

Directed vaccination against pneumococcal disease

Immunization strategies against commensal bacterial pathogens have long focused on eradicating asymptomatic carriage as well as disease, resulting in changes in the colonizing microflora with unknown future consequences. Additionally, current vaccines are not easily adaptable to sequence diversity and immune evasion. Here, we present a "smart" vaccine that leverages our current understanding of di

Variation benchmark datasets : update, criteria, quality and applications

Development of new computational methods and testing their performance has to be carried out using experimental data. Only in comparison to existing knowledge can method performance be assessed. For that purpose, benchmark datasets with known and verified outcome are needed. High-quality benchmark datasets are valuable and may be difficult, laborious and time consuming to generate. VariBench and V

Consensus recommendations on the classification, definition and diagnostic criteria of hip-related pain in young and middle-aged active adults from the International Hip-related Pain Research Network, Zurich 2018

There is no agreement on how to classify, define or diagnose hip-related pain-a common cause of hip and groin pain in young and middle-aged active adults. This complicates the work of clinicians and researchers. The International Hip-related Pain Research Network consensus group met in November 2018 in Zurich aiming to make recommendations on how to classify, define and diagnose hip disease in you

A load frame for in situ tomography at PETRA III

A load frame for in situ mechanical testing is developed for the microtomography end stations at the imaging beamline P05 and the high-energy material science beamline P07 of PETRA III at DESY, both operated by the Helmholtz- Zentrum Geesthacht. The load frame is fully integrated into the beamline control system and can be controlled via a feedback loop. All relevant parameters (load, displacement

New developments in madgraph/madevent

We here present some recent developments of MadGraph/MadEvent since the latest published version, 4.0. These developments include: Jet matching with Pythia parton showers for both Standard Model and Beyond the Standard Model processes, decay chain functionality, decay width calculation and decay simulation, process generation for the Grid, a package for calculation of quarkonium amplitudes, calcul