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Digital technologies are changing social work practices in profound ways. Today, digital devices are used by social workers in their everyday work; from assessing social benefit applications digitally, writing pre-formatted investigations and using chatrooms in treatment, to holding digital meetings with colleagues and clients. Digital technology is also utilized as a management instrument. Changi
Few genome-wide association studies (GWAS) account for environmental exposures, like smoking, potentially impacting the overall trait variance when investigating the genetic contribution to obesity-related traits. Here, we use GWAS data from 51,080 current smokers and 190,178 nonsmokers (87% European descent) to identify loci influencing BMI and central adiposity, measured as waist circumference a
Background: Adverse pregnancy outcomes, such as preterm delivery and hypertensive disorders of pregnancy, may be associated with higher future risks of heart failure (HF). However, the comparative effects of different adverse pregnancy outcomes on long-term risk of HF, and their potential causality, are unclear. OBJECTIVES: The authors sought to examine 5 major adverse pregnancy outcomes in relati
Background: Depression and suicidal behavior have been linked to increased blood-brain barrier (BBB) permeability. Platelet-derived growth factor receptor beta (PDGFR-β) is widely expressed in pericytes and promotes BBB integrity. Here, we investigated cerebrospinal fluid (CSF) levels of PDGFR-β in suicide attempters and healthy controls and correlated PDGFR-β to depression symptom severity. Metho
A presentation of Janken Myrdals book "Den predikande räven" (The preaching fox) which analyses the images in a late medieval illuminated manuscript of King Magnus Erikssons Law of the Realm.
Manufacturing processes can generally be classified as continuous, discrete or batch. An industrially well accepted way of structuring and controlling batch processes is presented in the ISA 88 standard (also known as IEC 61512). In exploring how this standard also could be used for discrete manufacturing processes, especially in robotic applications, different challenges and opportunities are fou
Immunotherapy, which involves strategies to activate, enhance or redirect immune responses to achieve long-lasting immunity, has the potential to play an important role in the treatment of a variety of diseases. This thesis, based on four original papers, highlights different approaches to modulate immune responses by specific targeting of antigen-presenting cells. The first two studies focuses o
