Filetype
Preterm infants benefit from combined supplementation of arachidonic acid (ARA), docosahex-aenoic acid (DHA) and choline, but ARA/DHA-rich oils are highly susceptible to lipid oxida-tion. This project aimed to develop and evaluate choline-enriched DHA/ARA oil-in-water emulsions with suitable physical and oxidative stability. Emulsions were prepared by high-pressure homogenization using two AquaCel
This thesis investigates the application of Artificial Intelligence (AI) and Machine Learning (ML) methods to improve carbon footprint estimation for Integrated Circuit (IC) components in automotive Cost Engineering (CE). The work addresses challenges faced by electrical cost engineers at Volvo Cars: the manual, time-consuming process of collecting component specifications, and estimating Carbon D
This thesis aims to develop and evaluate a fast design and optimisation workflow for corrugated tubes used in tubular heat exchangers by combining computational fluid dynamics (CFD) simulations and machine learning. A steady-state Reynolds-averaged Navier-Stokes (RANS) model was established to simplify the simulation process and reduce computational time. Based on the selected CFD setup, a CFD dat
The aim of this work is to redefine the concept of sensorimotor augmentation, extending it from wearable devices to supernumerary robotic upper limbs that are grounded and can be placed out of the physiological peripersonal space of the user. While the wearability of the supernumerary robotic limb (SRL) is not mandatory, the human-robot connection must be maintained through a wearable interface th
Childlessness is an increasingly visible phenomenon. Once predominantly associated with high-income settings, it now spans diverse cultural, economic, and political contexts, including the Global South. Among recent demographic shifts, childlessness has emerged as one of the most ideologically charged and widely debated topics in public discourse, particularly through media narratives. Although me
Light chain monoclonal gammopathy of undetermined significance (LC-MGUS) is an asymptomatic precursor of multiple myeloma (MM) and related disorders defined by abnormal free light chain (FLC) testing. Recently, revised FLC reference intervals were proposed by the iStopMM study group. We evaluated their performance in a large population-based cohort. MGUS cases were identified from the Danish Lymph
Natural polymers are promising sustainable materials for diverse applications. Xylans, major components of hemicellulose, exhibit origin-dependent substitution patterns that determine their physicochemical properties. Targeted enzymatic modification of these substituents offers a mild and precise approach for tailoring the polymer's characteristics. Glucuronidases (EC 3.2.1.139) and xylan α-1,2-gl
Despite extensive cataloging of carcinogenic exposures by the International Agency for Research on Cancer (IARC) and pharmacogenomic variation by resources such as PharmVar and CPIC, few platforms unify exposure, metabolic activation and detoxification, DNA damage, and genetic annotation within a single interactive visualization framework. This gap limits systematic evaluation of gene-environment
The initial adhesion of bacterial cells to implant surfaces is a critical step in the development of biofilms, complex microbial communities that are highly resistant to conventional antimicrobial treatments. Once established, these biofilms and their self-produced extracellular matrix are difficult to eradicate. As a result, there is growing interest in engineering implant surfaces that can effec
Surgery is often viewed as a lifesaving intervention, yet recovery depends just as much on what follows. The concept of individualised anaesthesia and analgesia in surgery challenges the traditional one-size-fits-all model by tailoring care to each patient's physiological and psychological profile, with the potential to improve outcomes, reduce complications, and enhance the patient experience. Ma
We study the time complexity of computing the (min,+) matrix product of two n×n integer matrices in terms of n and the number of monotone subsequences the rows of the first matrix and the columns of the second matrix can be decomposed into. In particular, we show that if each row of the first matrix can be decomposed into at most m1 monotone subsequences and each column of the second matrix can b
Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. To assess the benefits and harms of pain and sedation management for screening or treatment of retinopathy of prematurity in preterm infants compared to placebo, no intervention, or other interventions.
Background: Childhood (< 20 years) nervous system tumors manifest in some rare cancer syndromes but how commonly they present with familial clustering between various histological types is not well known at a nation-wide level. Our aim is to enhance understanding of familial risks in childhood nervous system cancers. Methods: We used the Swedish population and cancer data from years 1958–2021 to a
This paper describes the development of a new variant of stereoselective strain-release driven reactions (formal homo [3 + 2] dipolar cycloadditions) which utilize housane (1) to construct functionalized amino alcohols and pyridine-substituted cyclopentanes in two to three steps from simple and easily available building blocks (nitrones and pyridine N-oxides respectively).
Quantifications of phytoplankton biomass and species composition are crucial for monitoring biodiversity and population dynamics in aquatic environments, and both direct microscopic counts and fluorescence-based methods have been widely used for monitoring. Recent advancements in DNA metabarcoding offer an alternative way of easily assessing diversity and species composition. However, a comprehens
