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Popular Abstract in Swedish Tillväxthormon (GH) insöndras stötvis från hypofysen. Insöndringen är som högst nattetid, och de högsta nivåerna ses under puberteten för att därefter avta succecivt med ökande ålder. En av de vanligaste orsakerna till brist på GH är godartade tumörer i hypofys och hypofysnära områden där även behandling med kirurgi och strålbehandling kan bidra till hypofysinsufficiensIn childhood onset growth hormone deficiency (GHD) a reduction in cardiac left ventricular mass (LVMi) and impairment of cardiac systolic function, as well as in glomerular filtration rate (GFR) has been shown. In study I, we showed that a low dose of GH treatment for 10 months resulted in increased LVMi and kidney size. No significant improvement in cardiac systolic function or GFR, except for a

Systemic sclerosis (SSc) is an autoimmune disease that shows one of the highest mortality rates among rheumatic diseases. We perform a large genome-wide association study (GWAS), and meta-analysis with previous GWASs, in 26,679 individuals and identify 27 independent genome-wide associated signals, including 13 new risk loci. The novel associations nearly double the number of genome-wide hits repo

This thesis explores how second-hand clothing shopping contributes to the process of identity-making and social positioning among young adults in Germany and Hungary. Using the Consumer Culture Theory framework, the study investigates the social and cultural infrastructures that influence consumer behavior and emphasizes the symbolic meanings attached to second-hand shopping beyond traditional mot

In order to design and investigate the effects of vegetable oil based enzymatically produced liquid crystalline phases (LCPs), oat oil with 15% and 50% polar lipids contents (PL15, PL40) and with different storage conditions were incubated with Lipozyme TL and CalB. PL40 based LCPs were further investigated incorporating 1-10% aspartame (ASP) or ibuprofen (IBU) and all of the LCPs samples were ana

This project involved the testing and establishment of a base combustion procedure for the newly acquired Raddec Gen IV PYROLYSER and focused on the optimization and correction of the laboratory’s previous liquid scintillation counting (LSC) procedure using the Hidex 300 SL. The pyrolyser was verified to be operational and achieve satisfactory and consistent recoveries across the 6 combustion tub

Drawing upon literature from both impact assessment of development projects and agricultural research, the aim of this article is to analyse the pilot testing of a new multi-dimensional assessment framework for defining and evaluating the societal impact of agricultural research and corresponding education. The research approach involves an action research effort of pilot testing in three case stu

Metal-assisted chemical etching (MACE) is a cheap and scalable method that is commonly used to obtain silicon nano- or microwires but lacks spatial control. Herein, we present a synthesis method for producing vertical and highly periodic silicon microwires, using displacement Talbot lithography before wet etching with MACE. The functionalized periodic silicon microwires show 65% higher PEC perform

Business Rules (BR) and Business Processes (BP) are essential pillars in any Business Information System (BIS) and important areas of BIS design (BISD). Historically, BRs have been overlooked as a part of BISD. The Business Rules Approach (BRA) focuses on concepts and methods to remedy the neglected BR design and management. BRs in this perspective are stateless and concerned with the “what” of a

The demand for large-scale and long-term information on tree growth is increasing rapidly as environmental change research strives to quantify and forecast the impacts of continued warming on forest ecosystems. This demand, combined with the now quasi-global availability of tree-ring observations, has inspired researchers to compile large tree-ring networks to address continental or even global-sc

This article analyses the visions, careers, and companies of Jack Ma of Alibaba and Geng Le of Blue City. Jack Ma is a well-known business leader and visionary, whereas the less well-known Geng Le only began to receive more attention since launching a successful gay dating app in 2012. The article focuses on the personal narratives and visions of these two IT entrepreneurs. It provides new perspec

We have generated two reporter plasmids that either monitor expression of human papillomavirus type 16 (HPV16) E2 mRNAs using splice site SA2709 or HPV16 E1C mRNAs utilizing splice site SA2582. In plasmid pE2sLuc, the entire E2 open reading frame was replaced by the secreted luciferase (sLuc) reporter gene and in the pE1nLuc plasmid the E1/E1C open reading frame was fused in frame with the nanoluc

This study investigated the changes in the physical activity of Japanese breast cancer survivors during and after the state of emergency declaration (SOED) due to the spread of COVID-19. Participants were survivors of stage I-IIa breast cancer diagnosed between the ages of 18 and 60 years who wore a wearable device (Fitbit Versa) before and after the SOED period. Outcomes included steps per day on

The potential to source thermal energy from buried infrastructure such as tunnels and metro stations may offer significant potential to reduce the carbon dioxide emissions of heating and cooling, and reduce the costs associated with dedicated drilling for traditional ground-sourced systems. However, this remains a niche approach with few commercial schemes globally, partly due to high initial cost

Metal oxide nanoparticles are widely used in catalysis, photovoltaics, and gas sensing, where surface structure and oxidation state strongly influence performance. This work investigates how carrier gas composition, combined with in-flight heating, can be used to control the surface properties of metal oxide nanoparticles generated via the gas-phase method, spark ablation. Sn, Zn, and Al nanoparti