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During very long self-rating sessions there is a risk that respondents will be tired and/or lose interest. Is this a concern for users of long personality inventories, such that the reliability becomes threatened in the latter half when respondents have made hundreds of personality self-ratings? Two thousand three hundred and fifty two volunteers completed long (≈ 500 items) personality inventorie

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According to a widely held assumption, the main mechanism underlying motor learning in the cerebellum, such as eyeblink conditioning, is long-term depression (LTD) of parallel fibre to Purkinje cell synapses. Here we review some recent physiological evidence from Purkinje cell recordings during conditioning with implications for models of conditioning. We argue that these data pose four major chal

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γ-tubulin is an important cell division regulator that arranges microtubule assembly and mitotic spindle formation. Cytosolic γ-tubulin nucleates α- and β-tubulin in a growing microtubule by forming the ring-shaped protein complex γTuRC. Nuclear γ-tubulin also regulates S-phase progression by moderating the activities of E2Fs. The mechanism that regulates localization of γ-tubulin is currently unk

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BACKGROUND: Cholecystokinin (CCK) has been suggested to be involved in the development and course of acute pancreatitis. In the present study we measured plasma CCK concentrations in acute experimental pancreatitis (AEP) in the rat, and evaluated the role of circulating CCK levels on the initial pancreatic damage in pancreatitis. METHODS: Endogenous hyperCCKemia was induced by surgical biliodigest

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Objectives: In this thesis we studied the performance of active extension portfolios constructed by using momentum/contrarian strategies. Fundamentally, the difference between the 130/30 and the long-only asset classes is the relaxation from the long-only constraint. The main implication of this study is to find out whether the 130/30 strategy is value adding, in comparison to other actively manag

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In astrophysics, the ‘Goldilocks Zone’ describes the circumstellar habitable zone, in which planets, sufficiently similar to Earth, could support human life. The children’s story of Goldilocks and the Three Bears, one of the most popular fairy tales in the English language, uses this metaphor to describe conditions for life that are neither too hot nor too cold and neither too close to the sun nor

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In this commentary, I will review the latest findings on the Bicoid (Bcd) morphogen in Drosophila, a paradigm for gradient formation taught to biology students for more than two decades. "Seeing is believing" also summarizes the erroneous steps that were needed to elucidate the mechanisms of gradient formation and the path of movement of Bcd. Initially proclaimed as a dogma in 1988 and later incor

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Although treaty abuse is an increasingly occurring element in international legal arguments, especially in the sphere of international economic law, the concept is still viewed by many lawyers as suspicious, for several reasons. First, lawyers have doubts about the legal status of the treaty abuse doctrine. Second, as many lawyers would seem to believe, the concept of treaty abuse is imprecise-it

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As part of its efforts to secure a ‘net-zero society’, the UK government will take a strategic decision on the role of hydrogen in decarbonising homes within the next years. While scholars have recently advanced the social science research agenda on hydrogen technology acceptance, studies are yet to engage with the prospective dynamics of adopting ‘hydrogen homes’. In response, this study examines

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This paper introduces the comprehensive web-based IWG5 tool to evaluate energy consumption, renovation costs, and environmental impacts for European residential and office building renovations. Developed to support the SET-Plan Implementation Working Group 5 on Energy Efficiency in Buildings, the tool establishes benchmarks across five European climate zones by integrating dynamic building perform

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The identity of the enzymes responsible for lipase and cholesterol esterase activities in the small intestinal mucosa is not known. Because hormone-sensitive lipase (HSL) catalyzes the hydrolysis of acylglycerols and cholesteryl esters, we sought to determine whether HSL could be involved. HSL mRNA and protein were detected in all segments of the small intestine by Northern and Western blot analys