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Survival of Lactobacillus plantarum DSM 9843 (299v), and effect on the short-chain fatty acid content of faeces after ingestion of a rose-hip drink with fermented oats

In a controlled and randomised double-blind study, 26 healthy adult volunteers consumed, for 21 d, 400 ml of a rose-hip drink containing oats (0.7 g/100ml) fermented with Lactobacillus plantarum DSM 9843 (RHL; containing 5 x 10(7) cfu ml(-1)), and 22 volunteers in a second group the same amount of a pure rose-hip drink (RH). Significant increases in the total faecal concentration of carboxylic aci

Familial risk of pleural mesothelioma increased drastically in certain occupations : A nationwide prospective cohort study

Objective: We aimed to explore the effect of occupation on familial risk of pleural mesothelioma in a nationwide cohort study design. Method: The nationwide Swedish Family-Cancer Database includes all Swedes born after 1931 and their biological parents, totalling 16.1 million individuals with about 2.3 million cancer patients. Hazards ratios (HRs) were calculated adjusting for age, sex and region

Capsule and PspA Cooperatively Confer Resistance of Streptococcus pneumoniae to the Human Defensin HNP-1

Streptococcus pneumoniae resists host defenses through multiple surface factors, yet their specific contribution to protection against antimicrobial peptides remains incompletely understood. We examined the role of pneumococcal surface protein A (PspA) and the polysaccharide capsule in protection against the human defensin HNP-1. PspA conferred increased resistance to HNP-1-induced killing, shown

Improved Melatonin Dissolution Properties : A Way Forward for Treating Children with Sleep Disorders

Sleep problems, in particular the difficulty in initiating and maintaining sleep are important comorbidities in children and adolescents with attention deficit hyperactivity disorder (ADHD), accompanied by a range of negative consequences for both patients and their caregivers. Melatonin, a naturally occurring hormone that is important for coordinating the body's sleep-wake cycle, has been used to

Hård Af Segerstad Early Dietary Fiber Intake Reduces Celiac Disease Risk In Genetically Prone Child

Gastroenterology 2025;-:1–4 Early Dietary Fiber Intake Reduces Celiac Disease Risk in Genetically Prone Children: Insights From the TEDDY Study ietary fibers belong to a group of complex carbo- © 2025 The Author(s). Published by Elsevier Inc. on behalf of the AGA Institute. This is an open access article under the CC BY license (http:// creativecommons.org/licenses/by/4.0/). 0016-5085 https://doi.

https://www.teddy.lu.se/sites/teddy.lu.se/files/2025-04/Ha%CC%8Ard%20af%20Segerstad%20Early%20Dietary%20Fiber%20Intake%20Reduces%20Celiac%20Disease%20Risk%20in%20Genetically%20Prone%20Children_%20Insights%20From%20the%20TEDDY%20Study%20Am%20J%20Gastro.pdf - 2026-06-08

The longitudinal exercise trend among older Swedes aged 53-84 years - a 16-year follow-up study

Background: Many older adults are physically inactive and inactivity increases with age. This knowledge comes from cross-sectional studies. Cross-sectional studies may miss important trajectories within the older adults as a result of retirements, and poor health impact of promotional efforts. The aim of this study was to analyse, longitudinally, the annual effects of age group and birth cohort on

The longitudinal age and birth cohort trends of regular exercise among adults aged 16-63 years in Sweden: a 24-year follow-up study

Background: The aim of this study is to analyze longitudinally, based on four measurements at intervals of eight years, the annual effect of age group and birth cohort on regular exercise in the Swedish population from 1980-1981 to 2004-2005. Methods: We followed a randomly drawn subsample of individuals aged 16-63 years, interviewed by professional interviewers, from the Swedish Annual Level of L

Preventing and Preparing for Disasters – The Role of a Swedish Local Emergent Citizen Group

Disasters such as the storms that affected Sweden in 2005 and 2007 showed that citizens initially conducted a large part of the disaster response, such as clearing roads, giving psychosocial support to affected neighbours and repairing power lines in collaboration with power companies. As a result of these storms, an Emergent Citizen Group (ECG) was established in a village which continued to work

Genetic and Epigenetic Characterisation of Breast Tumours

Popular Abstract in Swedish Bröstcancer är den vanligaste cancerformen bland kvinnor i Sverige. Ungefär var tionde kvinna beräknas drabbas av bröstcancer, och i Sverige insjuknar ungefär 7.000 kvinnor årligen. Glädjande nog har överlevnaden förbättrats och nästan 90% lever 5 år efter sin diagnos och cirka två tredjedelar kan anses botade. Trots detta dör cirka 1.500 kvinnor i sjukdomen i Sverige vBreast tumours harbour a large amount of genetic and epigenetic alterations, which are associated with e.g. tumour aggressiveness, prognosis, and response to therapy. The heterogeneity of breast tumours is reflected in the identification of at least five molecular subtypes named basal-like, luminal A, luminal B, HER2-enriched and normal-like, which are believed to originate from different cell typ

Oral and faecal microbiota in volunteers with hypertension in a double blind, randomised placebo controlled trial with probiotics and fermented bilberries

Two probiotic products containing either live Lactobacillus plantarum strain DSM 15313 or bilberries fermented by the same bacterial strain were tested for their antihypertensive potentials and their impact on the oral and the faecal microbiota in hypertensive adults. The results showed that consumption of the tested products for three months did not reduce the blood pressure in adults with hypert

Longitudinal age-and cohort trends in body mass index in Sweden - a 24-year follow-up study

Background: The aim of this longitudinal study was to analyze whether mean Body Mass Index (BMI), assessed at four occasions, changed within different age groups and birth cohorts over time, i.e., between 1980/81 and 2004/05, after adjustment for possible confounders. Methods: A sample of 2728 men and 2770 women aged 16-71 years at study start were randomly drawn from the Swedish Total Population

Emissions from soy biodiesel blends: A single particle perspective

Biodiesel has recently reemerged as a common fuel. However, emissions from biodiesel combustion have been studied in much less detail than those from traditional petroleum-based diesel. In this experiment, emissions from the combustion of different fuel blends (BOO, B02, B20, B99, where the number after B indicates the percentage, by volume, of biodiesel in the fuel) in a VW TDi engine were analyz

Digested wheat gluten inhibits binding between leptin and its receptor

Background: Leptin resistance is considered a primary risk factor for obesity. It has been hypothesized that dietary cereal grain protein could cause leptin resistance by preventing leptin from binding to its receptor. Non-degraded dietary wheat protein has been found in human serum at a mean level of 41 ng/mL. Here, we report our findings from testing whether enzymatically digested gluten from wh

Risk of Cancer Following Hospitalization for Type 2 Diabetes

Objectives. Cancer and type 2 diabetes (T2D) are two common diseases that may share risk factors. We aimed at determining subsequent cancer risks in patients hospitalized for T2D in Sweden. Methods. T2D patients were obtained from the nationwide Hospital Discharge Register; cancers were recorded from the Swedish Cancer Registry. Standardized incidence ratios (SIRs) were calculated for cancer follo

Familial and neighborhood effects on psychiatric disorders in childhood and adolescence

Background: More knowledge is needed on potential associations between individual-, family-, and neighborhood-level factors and psychiatric disorders in children and adolescents. Aims: To examine associations between, individual-, family-, and neighborhood-level factors and incident internalizing (anxiety and mood) disorders and externalizing (ADHD and conduct) disorders in children and adolesc

Cross-cultural validation of a simple self-report instrument of physical activity in immigrants from the Middle East and native Swedes.

To investigate cross-cultural validity of a simple self-report instrument of physical activity intended to be used in Swedish health care. Methods: A validation study performed in 599 Iraqis (58% men) and 553 Swedes (53% men) aged 30-75 years living in the city of Malmö, Sweden. The self-report instrument by the Swedish National Board of Health and Welfare was compared to corresponding measures as

Limitations in the Use of Unipolar Charging for Electrical Mobility Sizing Instruments: A Study of the Fast Mobility Particle Sizer

A comparison between three different types of particle sizing instruments (fast mobility particle sizer, FMPS; electrical low pressure impactor, ELPI; and scanning mobility particle sizer, SMPS) and one condensation particle counter (CPC) was made to compare instrument response in terms of size distributions and number concentration. Spherical oil droplets in 39 different sizes, with geometric mea

Fine-particle emissions from solid biofuel combustion studied with single-particle mass spectrometry: Identification of markers for organics, soot, and ash components

The effects of combustion phase and fuel on smoke particle emissions from a wood stove operated with three different wood fuels and from a corn stove were investigated. A single-particle mass spectrometer (aerosol time of flight mass spectrometer (ATOFMS)) was used for time-and size-resolved chemical signatures and a scanning mobility particle sizer (SMPS) was used for online mobility size distrib

The presence of rheumatoid nodules at early rheumatoid arthritis diagnosis is a sign of extra-articular disease and predicts radiographic progression of joint destruction over 5 years

Objective: Radiographic damage is an important outcome in rheumatoid arthritis (RA). The disease course varies considerably, and there is a need for simple and reliable prognostic markers. The aim of the study was to determine the utility of early signs of extra-articular disease, manifested as rheumatoid nodules (RN), in predicting radiographic outcome. Methods: In a cohort (n = 1589) of consecut