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The Primacy of Right. On the Triad of Liberty, Equality and Virtue in Wollstonecraft's Political Thought

I argue along the following lines: For Wollstonecraft, liberty is independence in two different spheres, one presupposing the other. On the one hand, liberty is independence in relation to others, in the sense of not being vulnerable to their whim or arbitrary will. Call this social, or political, liberty. For liberty understood in this way, infringements do not require individual instances of int

Behavioural responses to co-occurring threats of predation and ultraviolet radiation in Daphnia

Organisms in the wild are faced with multiple threats and a common response is a change in behaviour. To disentangle responses to several threats, we exposed two differently sized species of the freshwater invertebrate Daphnia to solar ultraviolet radiation (UVR) and predation from either moving pelagic or benthic ambush predators. Using an advanced nanotechnology-based method, we tracked the thre

Globalisation, class and cultural identity at the end of hegemony

Globalisation traps, balkanisation, class polarisation, the dominance of transnational companies and the subordination of transnational migrants are all part of the imaging broadcast over the global media, and they merge with experiences of fear and joy in the countdown to the next millennium. The globalisation of fragmentation consists in driving a class wedge through the ethnic groups themselves

Unraveling the conformational landscape of amyloid precursor protein intracellular domain

The amyloid precursor protein intracellular domain (AICD), a cleavage product of amyloid precursor protein implicated in Alzheimer disease and amyloid lateral sclerosis, is a functionally important but structurally elusive intrinsically disordered protein. In this study, we investigate the conformational ensemble of a 35-residue AICD segment encompassing the conserved YENPTY motif using molecular

Exploring associations of housing, relocation, and active and healthy aging in sweden : Protocol for a prospective longitudinal mixed methods study

Background: While housing and neighborhood features have the potential to impact opportunities for active aging, there is a lack of knowledge related to how older people reason regarding their housing situation and how housing and fulfillment of relocation are associated with active and healthy aging. Objective: The objectives of Prospective RELOC-AGE are to study housing choices and relocation an

Development and Validation of a Modified Full Age Spectrum Creatinine-Based Equation to Estimate Glomerular Filtration Rate : A Cross-sectional Analysis of Pooled Data

BACKGROUND: The Chronic Kidney Disease in Children Study (CKiD) equation for children and the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation for adults are recommended serum creatinine (SCr)-based calculations for estimating glomerular filtration rate (GFR). However, these equations, as well as their combination, have limitations, notably the problem of implausible changes in

Physical Activity and Health Related Quality of Life in Relation to Allergic Disease among Adolescents: : Results from a Crosssectional Study

Aim: The overall aim of was to investigate the impact of self-reportedallergic disease on physical activity (PA) and health-related quality oflife (HRQoL) among adolescents.Methods: A cross-sectional analysis of 1 181 adolescents aged 13-14years (251 with current allergic disease), participating in the baselineinvestigation of the Southern Sweden allergy cohort, including a surveywith questions on

Visual acuity outcomes up to 12 years and risk factors for visual impairment in a national cohort of extremely preterm born children – The Extremely Preterm Infants in Sweden Study (EXPRESS)

Purpose: The Extremely Preterm Infants in Sweden Study (EXPRESS) followed a national cohort of extremely preterm born (EPT, i.e. <27 weeks) children until 12 years of age. This study aimed to investigate the longitudinal development of visual acuity (VA) in children born EPT, explore the predictive value of early visual assessments, and evaluate risk factors for visual impairment at the age of 12

LundOnline S2O UtaGrothkopf

LundOnline_S2O_UtaGrothkopf_short SUBSCRIBE TO OPEN (S2O) LIBRARIAN’S VIEW ON A COLLABORATIVE OA MODEL Uta Grothkopf Library, Documentation, and Information Services department European Southern Observatory (ESO) LundOnline, 9-10 November 2022 WORK CULTURE IN ASTRONOMY Observatories typically in remote places Community (researchers and librarians) closely connected Tradition of sharing and exchang

https://www.lundonline.lub.lu.se/sites/lundonline.lub.lu.se/files/2022-11/LundOnline_S2O_UtaGrothkopf.pdf - 2026-05-25

Flame soot characterization using combined multi-wavelength thermo-optical analysis and Raman spectroscopy

Multi-wavelength thermo-optical analysis (MW-TOA) and Raman spectroscopy are commonly used methods to study soot sampled on filters, in terms of carbon content, nanostructure, and absorption properties. In this work, these techniques were combined to study how these characteristic properties of soot change in premixed flames, 1) at various flame heights during soot maturation and 2) as a result of

Ultrasonic cavitation shock wave exfoliation dynamics of 2D materials revealed in situ by MHz XFEL imaging and multiphysics modeling

Using megahertz x-ray free electron laser imaging with x-ray pulses of ~25 femtoseconds and a machine-learning strategy, we have conducted comprehensive in situ imaging studies on the dynamics of cavitation bubble clouds in ultrasound fields at the SPB/SFX beamline of the European XFEL. The research unambiguously revealed the quasi-simultaneous implosion of multiple bubbles and simultaneous collap

Experimental insights on CIRLEM : Enhancing energy efficiency and flexibility in buildings

The growing complexity of urban energy systems, climate uncertainties, and geopolitical disruptions highlight the need for energy flexibility and smart management. Recent developments in smart buildings enable real-time adaptability and collective energy behavior through the deployment of Reinforcement Learning (RL), which optimizes energy use, integrates distributed resources, and enhances demand

Personalizing bariatric metabolic surgery : Predictors of weight-loss success and risk of weight recurrence

Background Bariatric metabolic surgery (Roux-en-Y gastric bypass [RYGB] and sleeve gastrectomy [SG]) effectively treats obesity and type 2 diabetes; however, weight loss varies, necessitating predictive factors. Methods We analysed 12- and 24-month weight loss data from 811 patients (RYGB or SG). Factor Analysis of Mixed Data and neural network (NN) modelling identified distinct patient phenotypes

ROS surface activity in three classes of engineered carbonaceous nanomaterials

Carbon Black (CB), graphene, and nanodiamonds represent three classes of manufactured carbonaceous nanoparticles consisting almost exclusively of insoluble material. Particle-related Reactive Oxygen Species (ROS) have been linked to in vivo and in vitro toxicity and determining particle ROS activity is an efficient way of estimating nanomaterial toxicity and assist in the safe-by-design developmen

Kommers-guide-fornyad-konkurrensutsattning

Microsoft Word - Kommers - förnyad konkurrensutsättning 2026-01-22 1 Senast uppdaterad: 2026-01-22 Innehåll Innehåll ....................................................................................................................................... 1 Om guiden .................................................................................................................................. 2 1

https://www.staff.lu.se/sites/staff.lu.se/files/2026-02/kommers-guide-fornyad-konkurrensutsattning.pdf - 2026-05-25

The influence of metformin treatment on the circulating proteome

Background: Metformin is one of the most used drugs worldwide. Given the increasing use of proteomics in trials, bioresources, and clinics, it is crucial to understand the influence of metformin on the levels of the circulating proteome. Methods: We analysed a combined longitudinal proteomics dataset from the IMPOCT, RAMP and S3WP-T2D clinical trials in 98 participants before and after metformin e

Phage homing endonuclease amplifies anti-defense genes to evade bacterial immunity

Bacteriophages must overcome diverse bacterial immune systems, yet the molecular principles enabling such escape remain poorly understood. Here, we show that the phage homing endonuclease SegB facilitates immune evasion by promoting the segmental amplification of anti-defense loci. The antiphage defense Septu inhibits phage T6 replication by cleaving the variable loop of tRNATyr. We show that SegB

Interactions between genetic predisposition to obesity, insulin resistance and type 2 diabetes risk, and food or beverage intake for incident type 2 diabetes : European Prospective Investigation into Cancer and Nutrition (EPIC) InterAct case–cohort study

Background: Limited evidence exists for effect modification of genetic characteristics on the associations of food consumption and incident type 2 diabetes (T2D). Objectives: We aimed to investigate whether the food-T2D association would vary by genetic susceptibility to metabolic traits. Methods: We analyzed data from 9542 incident T2D cases and a subcohort of 12,477 participants nested within th