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This study evaluated the adaptation of relapse prevention treatment, originally for substance use, to address problematic gaming in children and adolescents. The goal was to understand the feasibility of this treatment in child and adolescent mental health services from the clinicians’ perspective. Six clinicians, four women and two men aged 37–47 with 4–20 years of work experience, were interview
Popular Abstract in Swedish Utvärdering av stråldos och bildkvalitet i mammografi Bröstcancer är den cancerform som är vanligast hos kvinnor. Genom tidig upptäckt med bröströntgen, mammografi, kan man behandla sjukdomen i ett tidigare stadium och därmed minska dödligheten. Det är också möjligt att behandla på ett skonsammare sätt vid tidig upptäckt. Därför har man startat hälsokontroller, screeniMammography refers to the X-ray examination of the human breast, and is considered the single most important diagnostic tool in the early detection of breast cancer, which is by far the most common cancer among women. There is good evidence from clinical trials, that mammographic screening can reduce the breast cancer mortality with about 30%. The side effects include a small and age related risk
PURPOSE: Children with autism spectrum disorder (ASD) frequently exhibit atypical cognitive profiles, sensory processing challenges, sleep disturbances, and co-occurring psychiatric and somatic conditions. This exploratory prospective study, with a single-arm pre-post design, investigated the effects of a 10-12 weeks structured physical activity program on psychological symptoms, cognitive functio
In the present thesis, genetic abnormalities in pancreatic cancer were studied, with special emphasis on alterations of components involved in the transforming growth factor beta (TGFB) signaling pathway. In the first study, fluorescence in situ hybridization and cytogenetic analyses revealed aberrations of chromosome 18 in all 13 pancreatic carcinoma cell lines studied, in particular frequent bre
Popular Abstract in Swedish Tjocktarmcancer är en av de vanligaste cancerformerna i västvärlden. I Sverige drabbas årligen ca 5000 människor. Ungefär 10% av fallen går att härleda till ärftliga faktorer medan den övervägande delen orsakas av miljöfaktorer. Kända riskfaktorer är fysisk inaktivitet, fetma och rökning. Risken för cancer påverkas dock mest av den kost vi äter. Allmänt kan sägas att enSphingomyelin (SM) is present both in eucaryotic cells and the diet. Sphingomyelinase (SMase) hydrolyses SM and generates ceramide that has been implicated in the regulation of cell growth, differentiation and apoptosis. Previously a SMase with alkaline pH optimum was identified in the intestinal tract. The thesis studied the distribution pattern, the species difference and the clinical implicatio
Popular Abstract in Swedish Blåsexstrofi är en ovanlig och mångfasetterad missbildning. I hela Sverige föds cirka tre barn om året med blåsexstrofi. Bukvägg och urinblåsa är öppna nedanför naveln, så att man ser blåsans insida samt rinnande urin. Flickorna har en delad clitoris, framflyttad och trång slidöppning samt framflyttad ändtarmsöppning. Pojkarna har en kort, öppen penis, som ligger uppfälBladder exstrophy is a complex malformation seen in 1/30 000. Most children are subject to repeated operations, including pelvic osteotomy, genital and bladder neck reconstruction and sometimes bladder augmentation or a urinary reservoir, to achieve continence and a normal genital function. A retrospective study of all Swedish children born 1970-89 showed a low continence rate, 17% , and a high r
Popular Abstract in Swedish Elektrocochleografi (ECoG) är en metod som mäter de elektriska signaler som uppstår i innerörat när örat stimuleras med ljud. Signalerna uppstår i snäckans sinnesceller, de så kallade hårcellerna, och i nervcellerna som utgår från snäckan. Snäckan är det organ som omvandlar ljudets mekaniska energi till elektriska signaler i hörselnerven. Hörselnerven förmedlar signalerElectrocochleography (ECoG) is an objective method to evaluate cochlear electrophysiology. The recordings are considered to reflect the mechano-electric processes of the cochlea, and can indicate the presence of suspected endolymphatic hydrops. The aim of the present thesis was to investigate the value of transtympanic (TT) ECoG in the clinical diagnosis and management of Menière´s disease. The tr
Popular Abstract in Swedish Barn ar ofta bärare av luftvägsbakterien pneumokocker i de övre luftvägarna och det är barnen som anses vara den största reservoaren för bakterien i vårt samhälle. Vanliga pneumokockinfektioner såsom öron-, bihåle- eller lunginflammation föregås av att man bär på bakterien. De flesta barn som är bärare blir dock inte sjuka. Vuxna är mer sällan bärare av bakterien. PneuThe paediatric nasopharyngeal flora is regarded as the largest reservoir for Streptococcus pneumoniae, and the carrier state is always antecedent to infection and a prerequisite for dispersion of these bacteria. Pneumococci are the predominant aetiology of bacterial respiratory tract infections and a major cause of morbidity and mortality, in the most severe cases due to invasive pneumococcal dise
Popular Abstract in Swedish Intresset för utmattning har ökat både i Sverige och internationellt under de senaste årtiondena. Utmattning som begrepp är oklart definierat vetenskapligt, och det finns olika benämningar på utmattningstillstånd, som till exempel den något gammalmodiga benämningen neurasteni, som ännu finns kvar som diagnos-klassifikation (där även benämnt ”trötthetssyndrom”), kronisktThe interest in exhaustion has increased rapidly during the last few decades in many developed countries. In Sweden, prevalence of exhaustion increased by 50 percent on average between 1989 and 2005, and recent data reveals that exhaustion still remains at this higher level. Scientifically, exhaustion is not clearly defined. Chronic stress is acknowledged to give rise to exhaustion, but specific m
Popular Abstract in Swedish SAMMANFATTNING (SUMMARY IN SWEDISH) Jod är nödvändigt för utvecklingen och hälsan hos alla högre djur inklusive männi-ska, men det är ett relativt sällsynt grundämne. Man får i sig jod via kosten och det högsta jodinnehållet har fisk och skaldjur eftersom havssalt innehåller jod. Jod finns även i mejeriprodukter och i mindre mängder i grönsaker, men jodinnehållet i dessABSTRACT Background: Iodine is essential for development and growth as a constituent in thyroid hormones. Biological mechanisms for iodide uptake and concentration are very important, espe-cially as iodine is a relatively scarce element. Active iodide transport into thyroid fol-licular cells is mediated by the sodium/iodide symporter (NIS), powered by Na+/K+-ATPase. NIS is expressed also in extra
BACKGROUND: Integration of oncology and palliative care has been shown to increase quality of life in advanced disease. To meet the needs of the growing older population, integration of palliative care and geriatrics has been proposed but scarcely described.OBJECTIVES: The aim of this study was to integrate palliative care into geriatrics by a structured care guide, the Swedish Palliative Care Gui
BACKGROUND: The COVID-19 pandemic has seen many deaths, but the majority were for causes other than COVID-19. However, end-of-life care in all settings has been affected by measures limiting the spread of the virus, for patients with and without COVID-19. The Swedish coronavirus strategy was different compared to many other countries, which might have affected end-of-life care. The aim was to desc
On 19 September 2016, the UNGA adopted the New York Declaration for Refugees and Migrants through which States committed to developing two compacts: one on refugees and one on safe, orderly and regular migration. The Zero Drafts of the compacts were published on 31 January 2018 and 5 February 2018, respectively. The move towards the discussion and adoption of the global compacts comes in part in r
This paper describes the results of the conceptual and practical strategy work performed by the Swedish Ergonomics and Human Factors Society (EHSS) today. The rationale of EHSS is to strengthen the quality of ergonomics/human factors knowledge and practice in Sweden and form a multidisciplinary platform across disciplines and professions for collaboration and for knowledge sharing. EHSS gathers ab
Context Symptom relief is a key goal of palliative care. There is a need to consider complexities in symptom relief patterns for groups of people to understand and evaluate symptom relief as an indicator of quality of care at end of life. Objectives The aims of this study were to distinguish classes of patients who have different symptom relief patterns during the last week of life and to identify
Purpose The recruitment of participants to randomized controlled trials (RCTs) in palliative cancer care by health care professionals is often unsuccessful, which could result in failure to achieve study power. The purpose of this paper is to describe how health care professionals experienced recruiting patients and family caregivers to an RCT in palliative cancer care. Methods The study had a qua
Skatteflykt, skatteundandragande och aggressiv skatteplanering av företag underminerar staters förmåga att respektera, skydda och uppfylla mänskliga rättigheter eftersom stater berövas nödvändiga resurser för att förverkliga ekonomiska, sociala och kulturella såväl som medborgerliga och politiska rättigheter. Företags skattebeteenden har tidigare betraktats som en elefant i rummet inom Förenta natCorporate tax evasion, tax avoidance, and aggressive tax planning undermine states’ ability to protect, respect and fulfill human rights since states are deprived of necessary resources to realize economic, social and cultural rights as well as civil and political rights. Corporate tax has previously been called the elephant in the room within the United Nations’ (‘UN’) framework of Business and H
The paper provides an overview and preliminary results from ongoing research with the aim to evolve cross-laminated timber (CLT) into the next generation of Tailored Laminated Timber (TLT). This is done by exploring innovative concepts that optimize the mechanical performance, while simultaneously ensuring adherence to circular economy principles. The current study aims at investigating the potent
