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This paper estimates a "Grossman" model of demand for health. We measure health status on a 0 (dead) to 1 (full health) cardinal scale by the rating scale method and the time trade-off method. We also use a categorical measure of overall health status commonly used in quality of life measurements. To estimate the demand for health equations, the Tobit technique is used for the rating scale and tim
Statement of Purpose: Many chronic pulmonary diseases, including idiopathic pulmonary fibrosis (IPF), pulmonary hypertension (PH) and chronic obstructive pulmonary disease (COPD), are complex and poorly understood. While great progress has been made to elucidate the cellular and molecular pathways underlying these diseases, treatment options remain limited. The dynamic alterations in mechanical pr
Background In adults with serious respiratory illness, fatigue is prevalent and under-recognised, with few treatment options. The aim of this review was to assess the impact of graded exercise therapy (GET) on fatigue in adults with serious respiratory illness. Methods Electronic databases were searched to identify randomised controlled trials (RCTs) testing GET (involving incremental increases in
Rationale: Regular, low-dose, sustained-release morphine is frequently prescribed for persistent breathlessness in chronic obstructive pulmonary disease (COPD). However, effects on daytime sleepiness, perceived sleep quality, and daytime function have not been rigorously investigated. Objectives: We sought to determine the effects of regular, low-dose, sustained-release morphine on sleep parameter
The effort to electrify society has in recent years resulted in major changes in the transportation sector. Charging time remains a challenge in several applications such as transportation and heavy machinery. A proposed solution that shortens the energy replenishment time and adds flexibility in loading the grid is to battery-swapping: exchanging the depleted battery for a fully charged one. In s
Introduction Breathlessness is debilitating and increases in prevalence with age, with people progressively reducing their everyday activities to ‘self-manage’ it. This study aimed to evaluate the impact of breathlessness on function in terms of activities that have been reduced or ceased (‘compromised’) in older men.Methods A cross-sectional postal survey of Swedish 73-year-old man in the VAScula
Concerns over the earth’s ability to sustain itself over the long term as a consequence of human consumption of natural resources points towards sustainable development. Since a large proportion of human consumption is linked to buildings and construction, this means managing the construction process in more sustainable ways. Strategies that target greater material efficiency and which promote cir
The multi-objective optimal power management of multi-microgrid systems is solved in this paper. Minimizing the total cost and emission of the system are considered as the objective functions. The multi-objective particle swarm optimization algorithm is applied on a multi-microgrid system that consists of four microgrids each includes diesel generators, wind turbines, photovoltaic units, battery,
Healthcare organizations are under increasing pressure to account for their performance to outside constituencies. This chapter reviews the background, nature, and consequences of organized efforts to enhance transparency in healthcare. The driving forces differ between regions, but the trends are broad enough to result in similar developments across Europe. Market reforms and quality concerns cre
Background: Women with adverse pregnancy outcomes may have higher subsequent risk of chronic kidney disease, but the long-term independent risks and potential causality are unclear. Objective: This study aimed to determine long-term risks of chronic kidney disease associated with 5 major adverse pregnancy outcomes in a large population-based cohort, and to assess for familial confounding using co-
Intraosseous (IO) access is normally reserved for emergencies and critical care conditions when venous cannulation is not possible. Nonetheless, we present a case of IO insertion to a 56-year-old man, tetraplegic for many years due to progressive spinal muscular atrophy and with refractory suffering. The IO access was used for palliative sedation with propofol in a home care setting. The patient d
Bakgrund: Patienter med avancerad gastrointestinal (GI) cancer har en hög symtombörda, vilket ofta medför behov av akutsjukvård. Integration av tidig, hem-baserad specialiserad palliativ vård (SPV) tillsammans med tumörspecifik behandling kan påverka behov av akut sjukvård.Metoder: Vid initiering av palliativ kemoterapi randomiserades patienter med avancerad GI-cancer till tidig hem-baserad SPV inBackgroundPatients with advanced gastrointestinal (GI) cancer experience a high symptom burden which frequently necessitates emergency care. Integration of early home-based specialised palliative care (SPC) with tumour-specific treatments may impact emergency healthcare use.MethodsAt the initiation of palliative chemotherapy, patients with advanced GI cancer were randomised to early home-based SPC
Denna berättelse om Synergi mellan Strål- och Immun-Terapi har sitt ursprung i resultaten av försök som utfördes år 2001 vilka avsåg att kombinera tumörvaccin-behandling med strålterapi av Fischer-344 råttor med gliom-tumörer inokulerade i hjärnan.Med 3 omgångar tumörvaccin kombinerat med endast en fraktion strålterapi á 5Gy, överlevde sex av åtta behandlade djur (ca.75%). Detta dramatiska re
I undertake a comparative doctrinal study of the due diligence and liability provisions of the European Union’s Corporate Sustainability Due Diligence Directive, also accounting for some of the changes and omissions proposed under the so-called “Omnibus” process to streamline the already passed directive. In relation to the due diligence provisions, my main thrust is in comparing the directive to
The healthfulness of a dietary pattern is not merely measured in its content of nutrients, but also of the diversity of the ingredients present. The methods of analyzing dietary diversity, such as Minimum Dietary Diversity for Women (MDD-W) index and Dietary Species Richness (DSR), have been developed in the last decades, used to capture different forms of dietary diversity. Increased dietary dive
IntroductionYoung migrants are increasingly recognised as being particularly vulnerable to sexual violence. This vulnerability is largely structural, due to the different laws and policies impacting their access to rights and services. Post-structural approaches to policy argue that policies are not responses to existing problems, but rather that social issues are constructed through policy. They
Context: Chronic dyspnea is subjective but with objective (measurable) consequences. It is often poorly assessed because people have modified their lifestyles to avoid exertion that generates dyspnea. Objectives: This study sought any relationship between respondents’ self-reported long-term breathlessness limiting exertion (hereafter chronic dyspnea) and distance travelled from the room in which
ObjectivesPeople with serious illness approaching end of life often end up in emergency and hospital care, frequently against expressed preferences. Consequently, oncology trials record care days as a measure of treatment burden called “time toxicity.” However, this measure ignores the diminishing marginal utility of time: that the value of a day is higher when fewer remain. We aimed to incorporat
