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BACKGROUNDThe accuracy of estimation of kidney function with the use of routine metabolic tests, such as measurement of the serum creatinine level, has been controversial. The European Kidney Function Consortium (EKFC) developed a creatinine-based equation (EKFC eGFRcr) to estimate the glomerular filtration rate (GFR) with a rescaled serum creatinine level (i.e., the serum creatinine level is divi
Integration of fiber modification step with a modern pulp mill is a resource efficient way to produce functional fibers. Motivated by the need to integrate polymer adsorption with the current pulping system, anion-specific effects in carboxymethylcellulose (CMC) adsorption have been studied. The QCM-D adsorption experiments revealed that CMC adsorption to the cellulose model surface is prone to an
Electrostatic interactions play crucial roles in protein function. Measuring pKa value perturbations upon complex formation or self-assembly of e.g. amyloid fibrils gives valuable information about the effect of electrostatic interactions in those processes. Site-specific pKa value determination by solution NMR spectroscopy is challenged by the high molecular weight of amyloid fibrils. Here we rep
Direct cellular reprogramming has recently gained attention of cancer researchers for the possibility to convert undifferentiated cancer cells into more differentiated, postmitotic cell types. While a few studies have attempted reprogramming of glioblastoma (GBM) cells toward a neuronal fate, this approach has not yet been used to induce differentiation into other lineages and in vivo data on redu
As found in the health studies literature, the levels of climate association between epidemiological diseases have been found to vary across regions. Therefore, it seems reasonable to allow for the possibility that relationships might vary spatially within regions. We implemented the geographically weighted random forest (GWRF) machine learning method to analyze ecological disease patterns caused
This detailed volume presents a diverse set of methodological approaches designed to improve our understanding of bacterial infections from a wide range of bacterial species. Beginning with biofilms and subcellular compartments, the book explores transcriptional analysis, methods for studying plasmid dynamics, and tools for phylogenetic analysis of bacterial genomes, as well as bacterial effector
The emerging notion of hematopoietic stem and progenitor cells (HSPCs) as a low-primed cloud without sharply demarcated gene expression programs raises the question on how cellular-fate options emerge and at which stem-like stage lineage priming is initiated. Here, we investigate single-cell chromatin accessibility of Lineage-, cKit+, and Sca1+ (LSK) HSPCs spanning the early differentiation landsc
Aim: This randomised controlled trial evaluated changes in parental self-efficacy and children's weight, after a Child-Centred Health Dialogue about preventing obesity. Methods: We randomly assigned 37 Child Health Centres in Skåne county Sweden to provide usual care or the dialogue intervention. They included centres from high and low socioeconomic areas. The outcomes were changes in parental sel
AIMS: To describe the level of physical activity 6 months after an out-of-hospital cardiac arrest (OHCA) and to explore potential risk factors of a low level of physical activity.METHODS: Post-hoc analyses of the international multicentre Targeted Hypothermia versus Targeted Normothermia after Out-of-Hospital Cardiac arrest (TTM2) trial. At 6 months, survivors at 61 sites in Europe, Australia and
The complex dynamics of protein expression in plasma during hyperacute HIV-1 infection and its relation to acute retroviral syndrome, viral control, and disease progression are largely unknown. Here, we quantify 1293 blood plasma proteins from 157 longitudinally linked plasma samples collected before, during, and after hyperacute HIV-1 infection of 54 participants from four sub-Saharan African cou
BACKGROUND: Melanoma is a highly heterogeneous disease, and a deeper molecular classification is essential for improving patient stratification and treatment approaches. Here, we describe the histopathology-driven proteogenomic landscape of 142 treatment-naïve metastatic melanoma samples to uncover molecular subtypes and clinically relevant biomarkers.METHODS: We performed an integrative proteogen
Objectives Better understanding of societal factors associated with COVID-19 vaccination can have important implications for public health policy to increase uptake.Methods This study investigated sociodemographic determinants of COVID-19 vaccine uptake with ≥2 doses vs 0 doses, and ≥3 doses vs 2 doses, among adults (≥18 years) in a general population from Sweden followed from 27 December 2020 (n=
Background: Previous population-based studies investigating the relationship between physical activity and the gut microbiota have relied on self-reported activity, prone to reporting bias. Here, we investigated the associations of accelerometer-based sedentary (SED), moderate-intensity (MPA), and vigorous-intensity (VPA) physical activity with the gut microbiota using cross-sectional data from th
Two photoactive iron N-heterocyclic carbene complexes [FeII(btz)2(bpy)]2+ and [FeIII(btz)3]3+, where btz is 3,3’-dimethyl-1,1’-bis(p-tolyl)-4,4’-bis(1,2,3-triazol-5-ylidene) and bpy is 2,2’-bipyridine, have been investigated by Resonant Photoelectron Spectroscopy (RPES). Tuning the incident X-ray photon energy to match core-valence excitations provides a site specific probe of the electronic struc
2019-12-11 Dnr STYR 2019/1747 Juridiska fakultetens kompetensförsörjningsplan 2020–2022 Juridiska fakultetens strategiska plan omfattar perioden 2018–2026, och bygger på den strategiska planen för Lunds universitet för samma period. Fakultetens strategiska plan kompletteras av treåriga handlingsplaner av ett mer operativt slag med tydligt uppsatta och uppföljningsbara mål och åtgärder. Det handlar
Microsoft Word - General study plan_Medical Science, doctoral degree.doc Research Studies Board GENERAL STUDY PLAN FOR DOCTORAL STUDIES IN MEDICAL SCIENCE Scope: 240 credits Qualification: Degree of Doctor Details of approval: Approved by the Research Studies Board on 11 June 2018 Applies from: 1 January 2019 Amended: 10 December 2018 This is a translation of the Swedish version. In the event of a
Workshop – Den pedagogiska portföljen Sida 1 av 3 Centre for Engineering Education LTH KURSPLAN GB_F91 Datum 2012-10-08 Reviderad 2024-04-28 Workshop – Den pedagogiska portföljen (Teaching Portfolio Workshop) Workshop – Den pedagogiska portföljen är en valbar kurs inom den behörighetsgivande högskolepedagogiska utbildningen vid LTH. Att presentera och bedöma pedagogiska meriter med hjälp av en ped
Course Guide : PX36003 V23 Gerontologi - flervetenskapliga och integrativa perspektiv på åldrandet Course Guide The course Gerontology – Multidisciplinary and Integrative Perspectives on Aging consists of two sub- courses with a total of 5 (3+2) higher education credits (HEC): 1. Perspectives on aging, 3HEC 2. Implementation in own research (optional), 2HEC Please indicate in the Poll whether or n
Mall för kursplaner på grundnivå och avancerad nivå inom naturvetenskapliga fakulteten MVEC12 Kursplan för Riskanalys inom natur, miljö och hälsa, 15 högskolepoäng, Risk Analysis in Environment and Public Health 15 credits 1. Grundläggande uppgifter Fastställd av naturvetenskapliga fakultetens utbildningsnämnd xxx . Planen träder i kraft 2007-07-01. Kursen är på grundläggande nivå 2. Allmänna uppg
https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/mvec12_kursplan.doc - 2026-07-03
Guidelines on the Allocation of Decision-Making Powers and the Right to Sign Agreements at Lund University Page 1 of 2 REGULATORY DOCUMENT COVER PAGE Guidelines on the Allocation of Decision-Making Powers and the Right to Sign Agreements at Lund University Type of regulatory document: Guidelines Definition of the type of regulatory document: Guidelines establish how someone must or should act in t
