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Activation of the extracellular signal-regulated protein kinase cascade in the hippocampal CA1 region in a rat model of global cerebral ischemic preconditioning

A short period of sublethal preconditioning ischemia (3 min) followed by two days of reperfusion provides almost complete protection against ischemic cell death induced by a second (9 min) lethal ischemic episode. Here, we have investigated the extracellular signal-regulated protein kinase kinase and extracellular signal-regulated protein kinase, two kinases known to activate gene transcription an

Ethical Considerations in Nutrigenetics and Nutrigenomics

Ethics is the study of the normative dimensions of human relations and experiences. This chapter discusses such questions in relation to basic values in modern society. The normative foundations for the analysis are the values of human dignity, autonomy, freedom, equality, and solidarity, as well as the responsibilities of society toward its citizens, including freedom, security, and justice. The

Utgrävningarna av gravfältet i Vätteryd

Mellan åren 1955 och 1957 utförde Märta Strömberg (sedermera professor i arkeologi) och Rolf Petré (som senare blev fil. lic. i arkeologi) arkeologiska undersökningar av Vätterydsgravfältet i norra Mellby socken (L1990:1893 / Norra Mellby 1:1) ...

Making Blue Carbon : Coastal Ecosystems at the Science-Policy Interface

Klimatkrisen framstår mer och mer som det största hot människan någonsin ställts inför. Även om det politiska svaret kan beskrivas som avvaktande, pågår arbete för att på olika sätt minska klimatförändringarnas effekter, och hantera de risker vi kommer att ställas inför. Världssamfundet är enigt. Den globala medeltemperaturen bör inte öka med mer än 2 grader, och helst inte mer än 1,5 grader, jämfClimate change is a growing threat to mankind. The message from the scientific community is clear: we need to act fast and profoundly. The political response has, however, been slow. The likelihood that we will be able to meet our political climate goals only by reducing emissions is slim. Meanwhile is the interest around ways to capture carbon dioxide that has already been emitted on the rise. In

The prognostic performance of lactate in out of hospital cardiac arrest, a post hoc analysis of the TTM-trial

The purpose of this studywas to investigate the prognostic value of lactate at admission, 12-h lactate and 12-h lactate clearance for 30-day survival in comatose patients admitted after out of hospi tal cardiac Arrest (OHCA). Although measures of lactate have been successfully implemented in sepsis and trauma care, most OHCA studies are biased due to design and the results are conflicting. This is

Assessment of cooling integration with direct cooled windings

This paper presents and assesses the cooling integration of medium size electrical machines with distributed hair-pin type of windings. By introducing a hollow or profiled conductor the generated heat can be removed right where it is created. The cooling duct in conductor that can be connected either to series or parallel cooling flows increases DC resistance up to 1.5 times when comparing commerc

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As part of aiming towards a non-smoking hospital environment, staff at a Copenhagen university hospital were offered participation in a differentiated smoking cessation programme. This consisted of lectures, group therapy, follow-up visits and individually tailored nicotine replacement therapy free-of-charge for six weeks. Three hundred and seventy-four employees started the programme, with 353 co

Quality Assurance of Generative Dialog Models in an Evolving Conversational Agent Used for Swedish Language Practice

Due to the migration megatrend, efficient and effective second-language acquisition is vital. One proposed solution involves AI-enabled conversational agents for person-centered interactive language practice. We present results from ongoing action research targeting quality assurance of proprietary generative dialog models trained for virtual job interviews. The action team elicited a set of 38 re

Searches for New Physics Using Innovative Data Acquisition, Analysis, and Compression Techniques

När forskare blickar ut i universum ser de överallt spåren av en stor mängd osynlig massa. Massan finns där men det går inte att se den. Ungefär 80% av all massa i universum beräknas bestå av denna "mörka materia". Det är som att mänskligheten står på stranden och blickar ut över havet utan att veta vad vatten är. I partikelfysik studeras universums minsta beståndsdelar, elementarpartiklarna, för The high event rate delivered by the Large Hadron Collider (LHC) provides experiments with opportunities for new discoveries as well as challenges related to the large amounts of data recorded. Overcoming this requires innovative techniques in the three topics of this thesis: Data acquisition, data analysis, and data compression.In the data taking period of 2015-2018, the ATLAS experiment received

Ethopoeia as a progymnasma

An ethopoeia is an imagined speech assigned to a certain character. As a rhetorical exercise it is known from the progymnasmata of Theon, Hermogenes, Aphthonius and Nicolaus as well as contemporary rhetorical theorists. The purpose of the exercise was to teach the student the appropriate use of ethos and pathos for the assigned character. The paper will present the function of the ethopoeia as a p