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There is a growing evidence of the protective role of the Mediterranean diet (MD) on cancer. However, no prospective study has yet investigated its influence on lymphoma. We evaluated the association between adherence to the MD and risk of lymphoma and its subtypes in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. The analysis included 476,160 participants, recruite

Tumors are phenotypically heterogeneous and include subpopulations of cancer cells with stemlike properties. The natural product salinomycin, a K+-selective ionophore, was recently found to exert selectivity against such cancer stem cells. This selective effect is thought to be due to inhibition of the Wnt signaling pathway, but the mechanistic basis remains unclear. Here, we develop a functionall

Background: Epidemiological studies suggest that haem iron, which is found predominantly in red meat and increases endogenous formation of carcinogenic N-nitroso compounds, may be positively associated with lung cancer. The objective was to examine the relationship between haem iron intake and lung cancer risk using detailed smoking history data and serum cotinine to control for potential confound

The ability to capture alterations in the genome or transcriptome by next-generation sequencing has provided critical insight into molecular changes and programs underlying cancer biology. With the rapid technological development in single-cell sequencing, it has become possible to study individual cells at the transcriptional, genetic, epigenetic, and protein level. Using single-cell analysis, an

In the adult murine brain, neural stem cells (NSCs) can be found in two main niches: the dentate gyrus (DG) and the subventricular zone (SVZ). In the DG, NSCs produce intermediate progenitors (IPs) that differentiate into excitatory neurons, while progenitors in the SVZ migrate to the olfactory bulb (OB), where they mainly differentiate into inhibitory interneurons. Neurogenesis, the process of ge

De senaste åren har den digitaliserade gigekonomin och de nya arbetsformerna plattformsarbete och egenanställd etablerats i Sverige och övriga EU-länder. Gemensamt är att själva arbetet fragmentiserats och består av korta uppdrag åt ett flertal uppdragsgivare som förmedlas via en digital delningsplattform eller app. Den som utför en arbetsprestation gör det antingen som anställd eller som företaga

Faithful modeling of tissues and organs requires the development of systems reflecting their dynamic 3D cellular architecture and organization. Current technologies suffer from a lack of design flexibility and complex prototyping, preventing their broad adoption by the scientific community. To make 3D cell culture more available and adaptable we here describe the use of the fused deposition modeli

Background: Global transcriptional profiling of individual cells represents a powerful approach to systematically survey contributions from cell-specific molecular phenotypes to human disease states but requires tissue-specific protocols. Here we sought to comprehensively evaluate protocols for single cell isolation and transcriptional profiling from heart tissue, focusing particularly on frozen t

Frontotemporal dementia (FTD) is the second most prevalent type of early-onset dementia and up to 40% of cases are familial forms. One of the genes mutated in patients is CHMP2B, which encodes a protein found in a complex important for maturation of late endosomes, an essential process for recycling membrane proteins through the endolysosomal system. Here, we have generated a CHMP2B-mutated human

BackgroundA specific eHealth device, a surf tablet, was developed for bridging between advanced in-hospital care and children’s homes. Since little is known about determinators for parental eHealth usage, the study’s aim was to explore if parents’ usage of the device was associated with their eHealth literacy, or their satisfaction with their child’s healthcare or with the specific surf tablet.Met

This study reveals specific ion effects on particle formation during peristaltic pumping of a monoclonal Antibody (Antibody A). For this purpose, three anions in the direct Hofmeister series were selected, ranging from the kosmotropic SO42- to the more neutral Cl- and the chaotropic SCN-. Protein particle formation during peristaltic pumping is described primarily as a surface-driven mechanism. Th

Sepsis is a life-threatening condition caused by a dysregulated host response to an infection and is a leading cause of death worldwide. The condition is variable, which in combination with insufficient clinical markers, makes it challenging to predict when infection will progress to sepsis and to categorize patients into homogeneous patient subgroups. In this study, we demonstrate the use of acou

Användningen av mobila tjänster har ökat kraftigt de senaste åren, inte bara med privata abonnemang utan även vid användning med företagsmobiler. Vår undersökning syftar till att öka förståelsen för användande av SMS och MMS inom Svenska storföretag. Den modell vi utarbetat som stöd beskriver spridningen av SMS och MMS i organisationer. Den del av modellen vi undersöker behandlar innovationen, des

The alteration of release of calcium ions from biological tissue by electromagnetic stimulation has bien reported by several authors (Kaczmarec and Adey 1974:, Bawin et al. 1975, 1978; Bawin and Adey 1976; Blackman et al. 1979, l980a,å; Joines and Blackman 1980, l98l; Joines et al. l98O). Bawin etal. (1975) reported that 147 MHz radiofrequency (RF) electromagnetic radiation altered the release of The 'ion cyclotron resonance hypothesis' was explored by Liboff et al. (1987) in an experiment involving incorporation of calcium-45 (n5Ca2*) in mixed human lymphocytes. The geomagnetic horizontal field component was'adjusted to 2l pT. The experiment was first performed at an amplitude of the applied oscillating field of 150 pT and a sharp minimum was obtained at the frequency of l43Hz, which corr

At the emergency department (ED), it is important to quickly and accurately determine which patients are likely to have a major adverse cardiac event (MACE). Machine learning (ML) models can be used to aid physicians in detecting MACE, and improving the performance of such models is an active area of research. In this study, we sought to determine if ML models can be improved by including a prior

The Portable Ice Nucleation Chamber 2 (PINCii) is a newly developed continuous flow diffusion chamber (CFDC) for measuring ice nucleating particles (INPs). PINCii is a vertically oriented parallel-plate CFDC that has been engineered to improve upon the limitations of previous generations of CFDCs. This work presents a detailed description of the PINCii instrument and the upgrades that make it uniq

Kompetensförsörjningsstrategi för lärare vid naturvetenskapliga fakulteten Fakultetsstyrelsen Sida 1 av 1 FÖRSÄTTSSIDA STYRDOKUMENT Kompetensförsörjningsstrategi för lärare vid naturvetenskapliga fakulteten Typ av styrdokument: Strategi Beslutsfattare: Fakultetsstyrelsen Beslutsdatum: 2024-12-11 Diarienummer: STYR 2024/3056 Ikraftträdande: 2025-01-01 Giltighetstid: [2025-01-01 – 2027-12-31] Ersätt

https://www.naturvetenskap.lu.se/internt/sites/naturvetenskap.lu.se.internt/files/2025-01/Beslut%20241211%20kompetensfo%CC%88rso%CC%88rjningsstrategi%20fo%CC%88r%20la%CC%88rare%20vid%20N-fak.pdf - 2026-04-22

Microsoft Word - Allmän studieplan_medicinsk vetenskap 2019.doc Postadress Box 117, 221 00 LUND Telefon växel 046-222 00 00 Telefax 046-222 41 70 E-post info@med.lu.se Internet http://www.med.lu.se Forskarutbildningsnämnden ALLMÄN STUDIEPLAN FÖR UTBILDNING PÅ FORSKARNIVÅ I MEDICINSK VETENSKAP Omfattning: 240 högskolepoäng Examen: Doktorsexamen Fastställd: Fastställd av Forskarutbildningsnämnden de

https://www.intramed.lu.se/sites/intramed.lu.se/files/2022-12/allman-studieplan-medicinsk-vetenskap-doktorsexamen-2019-01-01.pdf - 2026-04-22

Microsoft Word - Allmän studieplan_medicinsk vetenskap_rev 2019-12-03_klar.doc Postadress Box 117, 221 00 LUND Telefon växel 046-222 00 00 Telefax 046-222 41 70 E-post info@med.lu.se Internet http://www.med.lu.se 1 1 Forskarutbildningsnämnden ALLMÄN STUDIEPLAN FÖR UTBILDNING PÅ FORSKARNIVÅ I MEDICINSK VETENSKAP Omfattning: 240 högskolepoäng Examen: Doktorsexamen Fastställd: 2018-06-11 Reviderad: 2

https://www.intramed.lu.se/sites/intramed.lu.se/files/2022-12/allman-studieplan-medicinsk-vetenskap-doktorsexamen-2020-01-01.pdf - 2026-04-22