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BACKGROUND: To explore the level of physical activity in a population based sample of older adults; to analyze the influence of pain characteristics and fear-avoidance beliefs as predictors of physical activity among older adults reporting chronic pain. METHODS: Demographics, pain characteristics (duration, intensity), physical activity, kinesiophobia (excessive fear of movement/(re) injury), se

Male breast cancer (MBC) is extremely rare and poorly characterized on the molecular level. Using high-resolution genomic data, we aimed to characterize MBC by genomic imbalances and to compare it with female breast cancer (FBC), and further to investigate whether the genomic profiles hold any prognostic information. Fifty-six fresh frozen MBC tumors were analyzed using high-resolution tiling BAC

Purpose: It is not yet possible to estimate the number of cases required for a beginner to become expert in laparoscopic radical prostatectomy. We estimated the learning curve of laparoscopic radical prostatectomy for positive surgical margins compared to a published learning curve for open radical prostatectomy. Materials and Methods: We reviewed records from 8,544 consecutive patients with prost

Whereas maintenance of hematopoietic stem cells (HSCs) is a requisite for life, uncontrolled expansion of HSCs might enhance the propensity for leukemic transformation. Accordingly, HSC numbers are tightly regulated. The identification of physical cellular HSC niches has underscored the importance of extrinsic regulators of HSC homeostasis. However, whereas extrinsic positive regulators of HSCs ha

Context: Newly discovered biomarkers ideally should prove clinical usefulness, provide additional detection, staging, and prognosis information to improve individual risk assessment, and potentially permit targeted cancer therapy. Objective: To review, display, and evaluate the current evidence regarding the biologic and analytic approach of urinary prostate cancer gene 3 (PCA3) in prostate cancer

Single cell gene expression assays have become a powerful tool with which to dissect heterogeneous populations. While methods and software exist to interrogate such data, what has been lacking is a unified solution combining analysis and visualisation which is also accessible and intuitive for use by non-bioinformaticians, as well as bioinformaticians.

Context: Prostate cancer (PCa) is one of the most common human malignancies and arises through genetic and epigenetic alterations. Epigenetic modifications include DNA methylation, histone modifications, and microRNAs (miRNA) and produce heritable changes in gene expression without altering the DNA coding sequence. Objective: To review progress in the understanding of PCa epigenetics and to focus

We use individual-level income data from archived taxation lists to study top-income earners in Sweden from 1909 to 1950. Using information on 21,055 individual taxpayers in two elite areas in greater Stockholm, we show that top incomes fell in real terms over this period, at a stable pace without obvious connection to the Great Depression or the world wars. The peak of inequality was related to tWe use individual-level income data from archived taxation lists to study top-income earners in Sweden from 1909 to 1950. Using information on 21,055 individual taxpayers in two elite areas in greater Stockholm, we show that top incomes fell in real terms over this period, at a stable pace without obvious connection to the Great Depression or the world wars. The peak of inequality was related to t

Due to their high aspect ratio and increased surface-to-foot-print area, arrays of vertical semiconductor nanowires are used in numerous biological applications, such as cell transfection and biosensing. Here we focus on two specific valuable biosensing approaches that, so far, have received relatively limited attention in terms of their potential capabilities: cellular mechanosensing and lightgui

I denna uppsats undersöks hur musiker upplever de förändringar som skett i musikbranschen de senaste tio åren till följd av den tekniska utvecklingen i form av bland annat gratisteknologier, exempelvis Spotify och Myspace, samt fildelning. I undersökningen har kvalitativa metoder i form av intervjuer använts. Vi har utgått från ett antal teoretiska begrepp som exempelvis medielogik, mediekonvergen

I denna uppsats undersöks hur musikkreatörer upplever de förändringar som skett i musikbranschen de senaste tio åren till följd av den tekniska utvecklingen i form av bland annat gratisteknologier och tjänster som Spotify samt fildelning. I undersökningen har kvalitativa metoder i form av intervjuer använts. Vi har utgått från ett antal teoretiska begrepp som exempelvis medielogik, mediekonvergens

Den här uppsatsen syftar till att undersöka hur guldpriset påverkas av olika makroekonomiska variabler samt avkastningen på alternativa tillgångar. Studien är gjord ur ett amerikanskt perspektiv och undersöker hur priset på fysiskt guld påverkas av prisindexet Consumer Price Index – All Urban Consumers (CPI-U), BNP-tillväxt, aktieindexet MSCI US Prime Market 750 Index och Treasury bills med tre må

Syfte: Syftet med denna studie är att undersöka vilka faktorer vid företagens börsintroduktioner, på NASDAQ OMX Stockholm och NGM Equity under åren 2001-2008, som påverkar sannolikheten att en efterföljande nyemission inträffar inom en kort tidsperiod (tre år). Metod: Studien är en kvantitativ undersökning där faktorer vid företagens IPO påverkar sannolikheten att en efterföljande SEO inträffar i

Digitalization has been frequently discussed within Competition Law over the last few years. It is not surprising that digital platforms have received a signif-icant amount of attention of among competition law experts and legislatures since a relatively few companies own the infrastructure needed for other com-panies to participate in the digital markets. The debate over the adequacy of our curre

Increased risk of Hodgkin lymphoma (HL) associated with personal history of several autoimmune diseases (ADs), such as rheumatoid arthritis, systemic lupus erythematosus, sarcoidosis, and immune thrombocytopenic purpura, are known. Whether there are other HL-related ADs and whether the increased risk of HL after ADs holds across sex, age, year of diagnosis, or HL histological subtype is unclear. W

Surgery or radiation therapy remain the standard curative treatments for newly diagnosed prostate cancer patients. Nonetheless, these aggressive treatments are associated with decreased quality of life with altered sexual and urinary functions. The objective was a systematic review of active surveillance protocols to investigate the role of histopathology and molecular markers in the active survei

Context: Although magnetic resonance imaging (MRI) is emerging as the most commonly used imaging modality for prostate cancer (PCa) detection, treatment planning, and follow-up, its acceptance has not been uniform. Recently, great interest has been shown in multiparametric MRI, which combines anatomic T2-weighted (T2W) imaging with MR spectroscopic imaging (MRSI), dynamic contrast-enhanced MRI (DC

Background: Patient enrolment into clinical trials is based on oral information and informed consent, which includes an information sheet and a consent certificate. The written information should be complete, but at the same time risks being so complex that it may be questioned if a fully informed consent is possible to provide. We explored patient representatives' views and perceptions on the wri

CV_TEGENFELDT_30MAY2013 May 30, 2013 CURRICULUM VITAE – DR. JONAS O. TEGENFELDT OVERVIEW Name: Jonas Tegenfeldt Personal number: 650122-1474 Gender: Male Citizenship: Swedish Contact information: Division of Solid State Physics Department of Physics Lund University PO Box 118 221 00 Lund Phone: 046 – 222 8063 Web: http://nanobio.ftf.lth.se/~tegen Current appointments 2013-present Associate profess

https://www.nano.lu.se/sites/nano.lu.se/files/cv_tegenfeldt_30may2013.pdf - 2026-05-07