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Two frameworks are proposed for extremum seeking of general nonlinear plants based on a sampled-data control law, within which a broad class of nonlinear programming methods is accommodated. It is established that under some generic assumptions, semi-global practical convergence to a global extremum can be achieved. In the case where the extremum seeking algorithm satisfies a stronger asymptotic s

In strategic management, the concept of organizational capabilities appears in two sets of related literatures: the resource-based view and the dynamic capabilities approach. The resource-based view treats organizational capabilities as unitary factors that explain cross-sectional industry performance differentials. The dynamic capabilities approach, on the other hand, treats organizational capabi

Neural transplantation holds promise for focal CNS repair. Owing to the shortage of human donor material, which is derived from aborted embryos, and ethical concerns over its use, animal donor tissue is now considered an appropriate alternative. In the USA, individuals suffering from Parkinson's disease, Huntington's disease, focal epilepsy or stroke have already received neural grafts from pig em

Befolkningen växer och andelen som vill bo i städer ökar stadigt vilket skaparbehov av ny mark att bygga bostäder på. Tidigare har de flesta städer och orterutvecklats genom att växa utåt, vilket har lett till förlust av naturområden ochjordbruksmark och ökat beroendet av bilar. Att bygga staden inåt istället, så kallad förtätning, är numera en populär strategi för att minska bostadsbristen. I denThe proportion of people living in densely built up areas is gradually increasing,forcing cities to generate new land to build homes upon. In this process there is a risk for an inexplicit decrease of green space. The green features ofneighbourhoods help to create a supportive environment for health and physicalactivity, thus a reduction of greenness may reduce the general well-being in thepopulat

Mikhlin's method for solving Laplace's equation in domains exterior to a number of closed contours is discussed with particular emphasis on the Dirichlet-Neutnann map. In the literature there already exit tyro computational modes for Mikhlin's method. Here a new mode is presented. The new mode is at least as stable as the previous modes. Furthermore, its computational complexity in the number of c

Background: Free and total human kallikrein 2 (hK2) might improve the discrimination between prostate cancer and benign prostatic hyperplasia. Concentrations of hK2 are 100-fold lower than concentrations of prostate-specific antigen (PSA); therefore, an hK2 assay must have a low detection limit and good specificity. Methods: PSA- and hK2-specific monoclonal antibodies were used in solid-phase, two

Let X = (X(t) : t greater than or equal to 0) be a Levy process. In simulation, one often wants to know at what size it is possible to truncate the small jumps while retaining enough accuracy. A useful tool here is the Edgeworth expansion. We provide a third order expansion together with a uniform error bound, assuming third Levy moment is 0. We next discuss approximating X in the finite variation

The objective was to develop evidence -based recommendations and a research and educational agenda for the non-pharmacological management of hip and knee osteoarthritis (OA). The multidisciplinary task force comprised 21 experts: nurses, occupational therapists, physiotherapists, rheumatologists, orthopaedic surgeons, general practitioner, psychologist, dietician, clinical epidemiologist and patie

This contribution concerns the development of generic methods and tools for robust optimal control of high-pressure liquid chromatographic separation processes. The proposed methodology exploits a deterministic robust formulation, that employs a linearization of the uncertainty set, based on Lyapunov differential equations to generate optimal elution trajectories in the presence of uncertainty. Co