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Non-invasive prenatal testing for aneuploidy and beyond: challenges of responsible innovation in prenatal screening.

This paper contains a joint ESHG/ASHG position document with recommendations regarding responsible innovation in prenatal screening with non-invasive prenatal testing (NIPT). By virtue of its greater accuracy and safety with respect to prenatal screening for common autosomal aneuploidies, NIPT has the potential of helping the practice better achieve its aim of facilitating autonomous reproductive

Performance evaluation of CoMP transmission schemes using measurements versus the COST 2100 channel model

Coordinated Multi Point (CoMP) transmission and reception techniques are used in order to improve the performance of single or multiple cells in wireless systems. A system using CoMP techniques is capable of jointly optimizing its transmission and/or reception and, hence, achieving higher performance. In this work, performance evaluation of three CoMP techniques are performed based on simulations

The Inherent Complexity of Agglomeration : Essays on the self-organization of urban economies

Den här avhandlingen kombinerar vetenskapen om komplexa adaptiva system med ekonomiska geografi för att beskriva och undersöka självorganiserande principer och drag i täta urbana ekonomier, särskilt med avseende på flöden av information och kunskap mellan människor som ger upphov till produktivitetsrelaterade externaliteter. Avhandlingen består av en kappa som presenterar det övergripande ramverkeThis doctoral thesis combines complexity science and economic geography in order to explore bottom-up, self-organizing principles within urban economies, in particular in relation to the flow of information and knowledge between people. The thesis consists of a kappa that covers the general theoretical framework and four papers. The papers cover urban scaling and intra-urban scaling analysis, loca

An ethnographic observation study of the facilitator role in an implementation process

BackgroundEven though the importance of a facilitator during an implementation process is well described, the facilitator’s role is rarely problematized in relation to the organizational context in terms of power and legitimacy; themes which have recently been brought to the fore when studying change in health care organizations. Therefore, in this article, we present a qualitative study with the

The influence of external nitrogen on carbon allocation to Glomus intraradices in monoxenic arbuscular mycorrhiza

The influence of external nitrogen (N) on carbon (C) allocation and processes related to phosphorus (P) metabolism were studied in monoxenic arbuscular mycorrhiza (AM) cultures of Daucus carota. Fungal hyphae of Glomus intraradices proliferated from colonized roots growing on solid medium into C-free liquid minimal medium with two different N and P levels. Furthermore, we exposed the colonized roo

Det sociala spelet om Romano Platso

This thesis has been taking a starting point from a micro-level that focuses social structures, ethnic segregation and processes of development as phenomena from different levels of perspectives. The research focuses on housing-conditions in the urban room and take a starting-point in 1992 when an increased number of immigrant households, depending on social welfare, moved into Herrgården (Manor-H

Just-in-Time : Hur industriella rationaliseringsstrategier formar arbetsdelning och kompetens

The emergence of new modes of production, referred to as flexible specialization, post-Fordism or neo-Fordism, has played an important and controversial role in the debate among economic geographers and industrial sociologists. In the discussion assumptions have been made about a process of up-skilling of the work force. In this study a random sample of 351 white- and blue-collar workers in eight

Plant-wide (BSM2) evaluation of reject water treatment with a SHARON-Anammox process

In wastewater treatment plants (WWTPs) equipped with sludge digestion and dewatering systems, the reject water originating from these facilities contributes significantly to the nitrogen load of the activated sludge tanks, to which it is typically recycled. In this paper, the impact of reject water streams on the performance of a WWTP is assessed in a simulation study, using the Benchmark Simulati

Memory Studies : The State of an Emergent Field

The article explores the degree to which memory studies has become established as an academic field. Although we acknowledge that there are drawbacks to formal institutionalization, we contend that it is useful to think strategically about the future of memory studies. We argue that three key developments must take place in order for a field to become institutionalized. First, individual scholars

Assessing the adaptive capacity of multi-level water governance : ecosystem services under climate change in Mälardalen region, Sweden

Adaptive and multi-level governance is often called for in order to improve the management of complex issues such as the provision of natural resources and ecosystem services. In this case study, we analyse the contemporary multi-level governance system that manages water resources and its ecosystem services in a fresh water lake in Sweden. We assess the relative importance and barriers of three c

Ten essentials for action-oriented and second order energy transitions, transformations and climate change research

The most critical question for climate research is no longer about the problem, but about how to facilitate the transformative changes necessary to avoid catastrophic climate-induced change. Addressing this question, however, will require massive upscaling of research that can rapidly enhance learning about transformations. Ten essentials for guiding action-oriented transformation and energy resea

Rheological aspects of swallowing and dysphagia : Shear and elongational flows

The physiological process of swallowing is not only a simple transfer of liquids or food boluses from the oral cavity to stomach, but also a complex succession of voluntary and involuntary phases that involve complex deformations and require the entire functionality of the oropharyngeal apparatus. When this functionality is affected, people experience dysphagia, which is described as a combination

A Comparison for the Sewerage System of Main Municipalities in Northern Cyprus

Popular Abstract in Swedish Avsaltning av havsvatten utgör en viktig källa för vattenförsörjning till befolkningen som bor vid Persiska viken, Medelhavet och Röda havet. De tre regionerna utgör ca 11,8 % av världens landyta och hade omkring 9 % av världens befolkning under 1950 och 2008, samt lika mycket enligt prognos för år 2050. Dessa områden är hemvist för 62 %, 58% och 60% av världens avsaltnIn this M.Sc. Thesis of a comparison for sewerage system of the three main municipalities of Turkish Republic of Northern Cyprus (T R N C) has been studied and discussed. The study covers the future population calculations for three municipalities, Nicosia, Famagusta and Kyrenia, by means of Turkish and European standards. The comparisons for sewerage system of the three municipalities are compare

Protection of Individual Minority Rights in the UN Global Sustainable Development Goals

Minorities falling under the Article 27 of the International Covenant on Civil, Cultural and Political rights, that is, individuals belonging to national, ethnic, religious or linguistic minorities possess characteristics that form part of their identity and differ from the characteristics possessed by the majority population of the state. Because of these particularities, minorities can be often

Alignment and orientation of Nanowires in a thin film under the influence of an electric field

Produktion av en nanotrådssolcell För att ta itu med miljöpåverkan från växthusgaser krävs en övergång till förnyelsebara energikällor. Ett exempel på en sådan källa är nanotrådssolceller. I mitt examensarbete har jag undersökt hur nanotrådar kan arrangeras på sådant sätt som krävs för att kunna omvandla solljuset till elektricitet. Global uppvärmning är ett hot som till stor del orsakas av utslThe demand for cheaper and more efficient solar cells is high. One way to decrease cost of material, while maintaining a high degree of efficiency, is to take advantage of nanomaterials. A thin film containing pn-junction nanowires can convert light with an efficiency comparable to traditional planar cells, while using a fraction of the material, and thus reduce costs. At the company Sol Voltaics

Den dolda vägen till förhandlingsbordet. En studie av indirekta bakvägssamtal mellan Israel och Hamas

Kidnapping is a frequent method for terrorists to force states to make concessions, which many times cause huge suffering and even death of the hostages. This study aims to analyse why indirect backchannel talks can facilitate negotiations with terrorists in order to save lives. The research regarding negotiations with political kidnappers is limited, which is why this study will be theory buildin