Filetype
In Sweden, extensive research is conducted to find alternative sources of energy that should partly replace the electric power production from nuclear power. With the ambition to create a sustainable system for producing energy, the use of renewable energy is expected to grow further and biofuels are expected to account for a significant part of this increase. However, when biofuels are burned or
The present study focuses on the preparation of poly(ethylene oxide) (PEO) nanocomposites based on the synthetic Laponite clay. The clay was added both in its pure form as well as organically modified with low molar mass poly(ethylene glycol) (PEG) components in order to enhance the compatibility between Laponite and PEO. Several PEG's with different end groups were used. Almost all of them were f
Sedimentological and morphological changes on the upper and lower shoreface during relatively stable sea-level highstand conditions have been investigated in the Pomeranian Bight, southern Baltic Sea, at time scales ranging from storm events to millennia. In order to cover that variety of time scales, different methods have been applied. Seasonal variations in the morphology of the upper shoreface
Time-resolved VUV laser spectroscopy has been performed to determine radiative lifetimes of several elements in atomic-beam systems. VUV radiation was generated by means of resonant four-wave mixing and stimulated anti-Stokes Raman shifting. Several methods to produce free atoms are presented and different techniques to determine radiative lifetimes are discussed. Doppler-free laser spectroscopy
The sensitivity of biosensors can be increased substantially by incorporation in a substrate recycling scheme. Based on the amplification of NAD+/NADH by the recycling reaction catalyzed by glycerol dehydrogenase (GDH) and diaphorase, NAD+/NADH can be determined amperometrically with around 1000 times higher sensitivity than for the substrate sensing mode. The sensitivity of enzyme electrodes were
This thesis consists of five papers (Papers A-E) treating problems in non-parametric statistics, especially methods of kernel smoothing applied to density estimation for stochastic processes (Papers A-D) and regression analysis (Paper E). A recurrent theme is to, instead of treating highly positively correlated data as ``asymptotically independent'', take advantage of local dependence structures b
Popular Abstract in Swedish Cellerna i kroppen är uppbyggda av fyra olika byggstenar: DNA, proteiner, fetter samt kolhydrater. Kolhydrater förknippas framförallt med energi och det pågår en intensiv debatt om kolhydraternas vara eller icke vara i vår kost. Kolhydraterna har dock också en helt annan funktion, en som är obestridligt oumbärlig för alla levande organismer. I denna roll förekommer de bGalectins are small soluble proteins defined by a conserved sequence motif that forms a defining β-galactoside binding site shared among galectins; adjacent binding sites give each galectin a unique fine specificity for a specific subset of galactose containing glycans. A wealth of data now suggests important roles of galectins in both cancer and inflammation. The aim of this project is to get a c
Helsingborg, a coastal city in southern Sweden, initiated a long-term redevelopment project called H+ in 2009, aiming to convert industrial harbor space in the city's south into a new, livable urban neighborhood and city center. The project aims to create an open and ‘tolerant city’ in Helsingborg over the next twenty years. In 2010-2011, H+ used an open-source planning method as a strategy to inc
Popular Abstract in Swedish De flesta cancerpatienter dör på grund av spridning av tumörceller till olika organ. Invasiv och metastaserande cancer svarar ofta inte på behandling och blir då i många fall dödlig. Leukemi är en elakartad sjukdom av blodceller, som påverkar blod-producerande organ. Den höga förekomsten av leukemi förekommer i äldre befolkningen och hos barn. Leukemi återfall och resiThe majority of current treatments used for treatment of prostate cancer (PCa) and leukemia are often limited to a narrow subsets of treated patients. As such, there still remains a significant scope for gaining deeper understanding of molecular mechanisms underlying cancer metastasis for improvement of targeted treatment. Elevated expression of a cell cycle regulator cyclin A1 initiated leukemia
Popular Abstract in Swedish Pankreascancer (cancer i bukspottkörteln) utgör fjärde orsak död i cancer. Det är den cancerform som har den dystraste prognosen av alla, med en 5-års överlevnad mindre än 6%. Sjukdomsrelaterade symptom uppträder ofta sent i förloppet och det saknas metoder för tidig diagnos varför de flesta av patienterna upptäckts i sent skede. Endast cirka 20 procent av patienterna kPancreatic cancer (PC) is the fourth leading cause of cancer-related deaths, with a 5-year survival less than 6%. It does not show any symptoms in its early stages, hence most (>85%) of the patients are diagnosed at late stage. At the time of diagnosis, metastases are frequently observed which make most patients unsuitable for curative surgical treatment and chemotherapy remains the only choice fo
Adsorption of mixed polymer solutions in good solvent containing polymers of different chain length has been studied by applying simulation techniques on a coarse-grained bead-spring polymer model. Fully flexible polymers at varying bead-surface interaction strength and different combinations of flexible, semiflexible, and stiff polymers at a single bead-surface interaction strength have been exam
Protein dynamics on the microsecond-millisecond time scales often play a critical role in biological function. NMR relaxation dispersion experiments are powerful approaches for investigating biologically relevant dynamics with site-specific resolution, as shown by a growing number of publications on enzyme catalysis, protein folding, ligand binding, and allostery. To date, the majority of studies
Among the numerous point vapor sources, microsecond-pulsed spark ablation at atmospheric pressure is a versatile and environmentally friendly method for producing ultrapure inorganic nanoparticles ranging from singlets having sizes smaller than 1 nm to larger agglomerated structures. Due to its fast quenching and extremely high supersaturation, coagulational growth already begins at the atomic sca
Molecular spiders are synthetic biomolecular walkers that use the asymmetry resulting from cleavage of their tracks to bias the direction of their stepping motion. Using Monte Carlo simulations that implement the Gillespie algorithm, we investigate the dependence of the biased motion of molecular spiders, along with binding time and processivity, on tunable experimental parameters, such as number
This paper reports on a joint numerical and experimental investigation of the release of potassium from biomass during gasification process. In this work, laser-induced breakdown spectroscopy (LIBS) was adopted to measure quantitatively the concentration of potassium from gasifying biomass. The effect of temperature on the potassium release is investigated in hot gas mixture of CO2, H2O with diffe
