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Quantitative analysis of conformational exchange contributions to H-1-N-15 multiple-quantum relaxation using field-dependent measurements. Time scale and structural characterization of exchange in a calmodulin C-terminal domain mutant

Multiple-quantum spin relaxation is a sensitive probe for correlated conformational exchange dynamics on microsecond to millisecond time scales in biomolecules. We measured differential H-1-N-15 multiple-quantum relaxation rates for the backbone amide groups of the E140Q mutant of the C-terminal domain of calmodulin at three static magnetic field strengths. The differential multiple-quantum relaxa

Land, water and the symbolic aspects of the Mesolithic in southern Scandinavia

This paper presents a preliminary model of the occupational history of the valley bottoms at the edges of the bed of the Quequén Grande River (Argentina) during the late Holocene. The ultimate goal of the research is to situate some aspects of technology, mobility, land-use patterns and settlement systems as a proximal consequence of a long-term process of 'lithification', that is, the positioning

Glutathione peroxidase and selenium in meat - Tissue and species variation, thermal stability and selenium speciation

Lipid oxidation is a major problem in muscle foods, leading to a loss in quality and nutritional value. It occurs in raw meat but is usually more pronounced in cooked meat. Since the demands of consumers for ready-to-eat foods have increased, the control of off-flavour in cooked meat is an important industrial problem. One way of minimising the development of lipid oxidation is to optimise the act

Kung Fotboll: Den svenska fotbollens kulturhistoria från 1800-talets slut till 1950

Popular Abstract in Swedish Avhandlingen behandlar den svenska fotbollens kulturhistoria från 1800-talets slut fram till år 1950. Det är berättelsen om hur spelet gradvis etableras, överkommer en mängd inre och yttre problem och konflikter, för att träda in i sin guldålder under 1940-talet. Mer konkret följs hur fotbollens medelklassdominerade maktelit försökte kontrollera skeendet inom en sport pThis thesis concerns Swedish football´s cultural history from the end of the nineteenth century to 1950. It is the story of how the game was gradually established, and overcame a great number of internal and external problems and conflicts, before entering its sporting and cultural golden age during the 1940s. I demonstrate how this game´s middle-class dominated power elite tried to control the de

Reflexive Legitimacy in International Arbitration

The purpose of this study is to investigate the process of international commercial arbitration and its development as a legal and cultural entity. The recent changes within the field of arbitration are intimately related to the intensification of global exchanges and the growth of “world society”. It follows that any sociological study of arbitration must be conducted in light of the on-going glo

Development and Implementation of Cardiac Event Detectors in Digital CMOS

This doctoral dissertation presents the development and digital hardware realization of cardiac event detectors. Implantable medical appliances, as the cardiac pacemaker, have progressed from a life sustaining device to a device that considerably improves life quality for all ages. The number of electronic devices and household appliances in everyday live has an ongoing exponential growth. The

Det klyvbara ämnet : Diskursiva ordningar i svensk kärnkraftspolitik 1972­-1980

Popular AbstractSveriges första stora kärnkraftsreaktor togs i bruk 1972. Samma år kom kärnkraften att för första gången på allvar ifrågasättas i den svenska riksdagen. Under loppet av ett par år förvandlades kärnkraftsfrågan till den nutida svenska politikens kanske mest kontroversiella och omdebatterade fråga. I denna avhandling analyseras den riksdagspolitiska debatten om kärnkraften mellan åreThis study applies a qualitative discourse theoretical method to analyse the central argumentation in the parliamentary debate on nuclear power in Sweden during 1972­1980, reconstructed from official documents such as governmental and parliamentary bills, committee reports, parliamentary debate protocols, and official commission reports. Particular concern is directed to the process in which vari

Long term anti-tumour necrosis factor alpha monotherapy in rheumatoid arthritis: effect on radiological course and prognostic value of markers of cartilage turnover and endothelial activation.

Objectives: To investigate the effect of prolonged neutralisation of tumour necrosis factor alpha (TNFalpha) on the radiological course in rheumatoid arthritis (RA). To assess whether the radiological course can be predicted by clinical variables or biological markers of cartilage and synovium turnover and of endothelial activation. Patients and methods: Forty seven patients with active RA enrolle

Hustadt, Inshallah : Learning from a participatory art project in a trans-local neighbourhood

My PhD dissertation investigates relationships between contemporary art and spatial practices It emphasising the creation of platforms for public participation as interventions into urban regeneration processes. The project has two essential objectives: a. To identify the potential within contemporary art for a critical analysis of an urban de velopment process from the location, in dialogue with

Advert saliency distracts children's visual attention during goal-directed internet use

The general research question of the present study was to assess the impact of visually salient online adverts on children's task-oriented internet use. In order to answer this question as reliably as possible, an experimental study was constructed in which 9-year-old and 12-year-old Swedish children were asked to solve a number of tasks while interacting with a mockup website. In each trial, web

Chinese women living with cervical cancer- Health-related Quality of Life, Sense of Coherence, lived experience

Due to the unavailability of culture-appropriate measurements of health-related quality of life (HRQOL) in China, knowledge about the HRQOL of women with cervical cancer, particularly in Mainland China, is poor. Such knowledge is greatly needed to inform nursing practice. Thus the main aim of this thesis was to investigate longitudinally the HRQOL trajectory in Chinese women from when cervical can

Parallelization of a multiconfigurational perturbation theory

In this work, we present a parallel approach to complete and restricted active space second-order perturbation theory, (CASPT2/RASPT2). We also make an assessment of the performance characteristics of its particular implementation in the Molcas quantum chemistry programming package. Parallel scaling is limited by memory and I/O bandwidth instead of available cores. Significant time savings for cal

Global Norms for Public Acceptance for Desalination and Water Ruse

Desalting technologies and fresh water production has been developed over the years, including primarily thermal and membrane processes. Five different types of desalination technology were studied and compared for long-term of use namely, thermal processes include multistage flash evaporation (MSF), multiple effect evaporation (ME), and vapor compression (VC) and membrane processes contain revers

Walking as a transport mode : Examining the role of preconditions, planning aspects and personal traits for the urban pedestrian

The overall aim of this thesis is to examine how walking as a transport mode is constructed in the planning realm, affected by the built environment and perceived by the individual. This aim is related to the following research questions: (1) How are pedestrians and walking understood, constructed and perceived in the planning context? (2) How does individual traits and the built environment affec

Contributions to Securing Software Updates in IoT

The Internet of Things (IoT) is a large network of connected devices. In IoT, devices can communicate with each other or back-end systems to transfer data or perform assigned tasks. Communication protocols used in IoT depend on target applications but usually require low bandwidth. On the other hand, IoT devices are constrained, having limited resources, including memory, power, and computational

Att jobba vid två skärmar inte alltid optimalt

Hur påverkas synergonomin av att jobba vid fler och stora skärmar? Det ska Hillevi Hemphälä, doktor i arbetsmiljöteknik, undersöka i en treårig forskningsstudie.– Enligt de gamla rekommendationerna ska datorskärmar på upp till 26 tums storlek placeras på 90 centimeters avstånd för att vi ska undvika huvudrörelser i sid- och höjdled. Men många skrivbord i dag är 80 centimeter och datorskärmarna oft

Fungal and bacterial contributions to decomposition in terrestrial and aquatic ecosystems

Microbial decomposers process a great majority of net primary production in the biosphere and regulate carbon (C) and nutrient cycling. Microbial communities are extremely diverse and often disregarded from global C-cycling models, but one strategy to overcome this challenge is to focus on the major decomposer groups: fungi and bacteria. These groups have distinct life strategies and are different