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Objective To delineate organ-specific and systemic drivers of metabolic dysfunction-associated steatotic liver disease (MASLD), we applied integrative causal inference across clinical, imaging, and proteomic domains in individuals with and without type 2 diabetes (T2D). Methods Bayesian network analyses and complementary two-sample Mendelian randomization were used to quantify causal pathways link
Simulation methods in breast imaging offer advantages over clinical trials in terms of improved reproducibility, reduced need for patient exposure to radiation, increased flexibility, and more clearly defined ground truth. Simulation also allows for improved representation of anatomical variations and variations in acquisition parameters and breast positioning related to multimodality imaging. The
Background: Chimney endovascular aneurysm repair (chEVAR) techniques have been described to manage a group of patients who are unsuitable for either open aortic aneurysm surgery or a variety of standard endovascular repair techniques. The aim of this study was to assess the long-term clinical outcomes of chEVAR in emergency settings for patients with abdominal aortic aneurysms that have complex mo
Aim: Many populations of migratory birds are currently declining. Understanding space use throughout the entire annual cycle, as well as migratory connectivity (i.e., geographic linkage of individuals and populations across different stages of the annual cycle), can improve our ability to identify factors driving population declines and influencing extinction risk. The main objectives of our study
Structures of Affect: Gender and Political Culture in China examines the central role of affect and gender in shaping personality, community, nationhood and political discourse in contemporary China.Drawing on (auto)ethnography, interviews, films, podcasts, and cultural and artistic productions from the 2000s to 2025, this book demonstrates how authoritarian rule is sustained through complex affec
Quantum computing has attracted substantial attention from researchers across various fields. In case of the symmetric key cryptography, the main problem is posed by the application of Grover’s search. In this work, we focus on quantum analysis of the lightweight block cipher LED. This paper proposes an optimized quantum circuit for LED, minimizing the required number of qubits, quantum gates, and
It is a common practice for symmetric-key ciphers is to encode a cryptanalysis problem as an instance of the Mixed Integer Linear Programming (MILP) and then run the instance with an efficient solver. For this purpose, it is essential to model the components in a way that is compatible with the MILP formulation while preserving the characteristics of the cipher. In this work, we look at the proble
Objectives This study aimed to examine associations of sociodemographic factors, cervical cancer, urogenital infections (cystitis, vulvovaginitis, and vaginosis), and parity with pelvic inflammatory diseases (PID). Methods Nationwide open cohort study including 4,097,075 women aged 15 years or older during the study time period (2002–2018). Cox proportional hazard regression models were used to es
Expanding health insurance can either increase or decrease pregnancies and births, depending on how it affects access to contraception and the financial costs of childbearing. I study the Affordable Care Act’s Medicaid expansion using difference-in-differences models and state-level data on contraceptive provision, births, and abortions, synthesizing analysis of these outcomes to distinguish the r
The objective of the recently published World Health Organization Reporting System for Lymph Node, Spleen, and Thymus Cytopathology (WHO system) is to standardize the diagnostic approach to fine-needle aspiration biopsies of hematolymphoid tissues. By categorizing specimens into five diagnostic groups—inadequate/insufficient/nondiagnostic, benign, atypical, suspicious for malignancy, and malignant
This study presents a modular approach for the synthesis of multifunctional affinity sorbents, facilitating molecular separation via magnetic molecularly imprinted polymers. A magnetic propranolol-imprinted polymer (MIP) nanocomposite with superparamagnetic characteristics was synthesized through precipitation polymerization process coupled with coprecipitation methods. Initially, the propranolol-
Introduction: Maximal safe resection is established goal of WHO grade 2 low-grade gliomas (LGG). Asleep motor mapping offers an alternative to awake surgery for tumors near motor areas and has been shown to be safe and effective in expert centers. Research question: We aimed to identify predictors of postoperative motor deficits, and describe patient selection and intraoperative mapping techniques
