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The field of molecular phylogenetics is being revolutionized with next-generation sequencing technologies making it possible to sequence large numbers of genomes for non-model organisms ushering us into the era of phylogenomics. The current challenge is no longer how to get enough data, but rather how to analyse the data and how to assess the support for the inferred phylogeny. Here, we focus on o

AIM: This retrospective study evaluated long-term effects of percutaneous transluminal renal angioplasty (PTRA) in atherosclerotic renal artery stenosis (ARAS), and predictors of benefit on blood pressure (BP). METHODS: During 1997-2003, 234 patients (age 69+/-11 years, 138 [59%] males) underwent PTRA for ARAS at Malmö Vascular Centre. Cure was defined as diastolic (D)BP<90 mmHg and systolic (S)BP

BACKGROUND: Knowledge of the size and location of ischemic myocardium during acute coronary occlusion could provide decision support before reperfusion therapy. Electrocardiogram (ECG) scores based on the number of leads and the sum of ST-segment elevation have been unreliable in quantifying ischemia. We aimed to develop a new method to graphically display ischemic myocardium from simulated ECGs (

Ever since IT started to become important and strategic assets in organizational practices, systems acquisitions have been a challenging and complex endeavor. There are seemingly never ending reports of unsuccessful IT acquisitions and lack of systems acquisition competence (beställarkompetens in Swedish). The aim of this thesis is to shed deeper light on what systems acquisition competence is abo

Embedded computer systems are subject to a multitude of requirements. These include real-time requirements, that is, such computers must respond to external events within limited time. Many systems, such as satellites and telephone switches, must also operate unattended for long periods of time. They must not fail due to defective software. Modern object-oriented programming languages, particular

Blue light (400–500 nm) alleviates overexposure risks associated to UV light and has therefore gained increased interest in multiple applications. This meta-analysis deals with decontamination of E. coli through the use of blue light based from nine recent publications identified via a systematic literature search. In these studies, various pathogenic and non-pathogenic E. coli strains grown in nu

Recombination strongly impacts sequence evolution by affecting the extent of linkage and the efficiency of selection. Here, we study recombination over the Z chromosome in great reed warblers (Acrocephalus arundinaceus) using pedigree-based linkage mapping. This species has extended Z and W chromosomes (“neo-sex chromosomes”) formed by a fusion between a part of chromosome 4A and the ancestral sex

Examining the archaeological material of the modern period, over a period of the last 500 years, this open access book presents a series of case studies that challenges the fallacy of Nordic egalitarianism. The widening gap between rich and poor Western countries is now a well-known phenomenon and, while Scandinavia has often been hailed as one of the regions where inequality has been the lowest,

Despite a long history and the vast number of applications demonstrated, very few market products incorporate acoustophoresis. Because a human operator must run and control a device during an experiment, most devices are limited to proof of concepts. On top of a possible detuning due to temperature changes, the human operator introduces a bias which reduces the reproducibility, performance and rel

Background: Selection pressure exerted by pathogens can influence patterns of genetic diversity in the host. In the immune system especially, numerous genes encode proteins involved in antagonistic interactions with pathogens, paving the way for coevolution that results in increased genetic diversity as a consequence of balancing selection. The complement system is a key component of innate immuni

Background: The World Health Organization has adopted a resolution on sepsis and urged member states to develop national processes to improve sepsis care. In Sweden, sepsis was selected as one of the ten first diagnoses to be addressed, when the Swedish government in 2019 allocated funds for patient-centred clinical pathways in healthcare. A national multidisciplinary working group, including a pa

As a part of our continuous search for oncogenic viruses in bronchial cancer, we extended our HPV studies to analyse also SV40, BKV, JCV and HCMV sequences in bronchial cancer and related these data with p53 codon 72 polymorphism. Fresh tumor samples from 78 patients with lung cancer were analysed for SV40, BKV, JCV, HCMV and HPV sequences by PCR. HPV genotypes were determined using reverse blot h

Background: Proton radiotherapy (RT) is an attractive tool to deliver local therapy with minimal dose to uninvolved tissue, however, not suitable for all patients. The aim was to explore complications, especially severe late complications (grades 3–4), following proton RT delivered to a complete Swedish cohort of paediatric patients aged <18 years treated 2008–2019. Material and Methods: Data was

Penelope Delta was a writer of books for children in the beginning of the twentieth century in Greece. Delta was active when the national project was at its peak. Delta's own participation in the national project consisted of writing for children in a vernacular language and belonging to a group of intellectuals actively promoting modernization in other aspects than only political and technologica

Background: Little is known about whether the protective effect of marriage on alcohol use disorder (AUD) varies by cultural background. Aims: Using Swedish national data, we examined whether marriage is associated with a stronger reduction in AUD risk among Swedes of a Swedish background (i.e. those with two Swedish-born parents) compared to Swedes with a foreign background (i.e. one or two forei

Occupancy is one of the primary contributors to the energy performance gap, defined as the difference between actual and predicted energy usage, in buildings. This paper limits its scope to residential buildings, where occupant-centric consumption often goes unaccounted for in standard energy metrics. This paper starts from the hypothesis that a simple occupant energy efficiency label is needed to

The cultivated peanut (Arachis hypogaea L.) is an important oilseed crop worldwide, and fatty acid composition is a major determinant of peanut oil quality. In the present study, we conducted a genome-wide association study (GWAS) for nine fatty acid traits using the whole genome sequences of 160 representative Chinese peanut landraces and identified 6-1195 significant SNPs for different fatty aci

It is always challenging to try to transmit and transform values and attitudes within a school in a democratic society, and even more challenging to do so in a group of socially disadvantaged pupils. What happens in a classroom where disadvantaged pupils in the upper secondary school meet teachers who have a general obligation to transmit democratic values? This article is a case study of the inte

Ämnet för denna uppsats är näthat vilket kan innebära brott som förolämpning, förtal och ofredande. Men trots att ärekränkningslagstiftningen är vedertagen är den inte helt vattentät. Ärekränkning är ett gammalt hedersbrott som sedan lång tid tillbaka har reglerats i svensk straffrätt. I Sveriges strafflag från 1864 (SL) avsåg förtalsbestämmelsen att värna om den enskildes goda namn och medborgerlThe subject of this essay is net hate, which can implicate felonies such as insult, defamation and harassment. Even though the Swedish rules specific to defamatory acts are recognized, they are far from comprehensive. Defamation, an offence that violates someone’s honor, is an old crime in the Swedish history of law. In the Criminal Law (SL) from 1864 the rule of defamation was intended to protect