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Effects of chronic citalopram treatment on central and peripheral spontaneous open-field behaviours in rats
The spontaneous open-field behavioural effects of 10 days of chronic treatment with two clinical doses (10 and 20 mg/kg daily) and one high/toxic dose (100 mg/kg daily) of the selective serotonin reuptake inhibitor citalopram (delivered subcutaneously by implanted osmotic pumps) were examined in rats. Central and peripheral arena locomotor and rearing activities were recorded simultaneously, and t
Framtidsveckan 2019 program final 190923
Framtidsveckan VETENSKAPSVECKA | 14–20 OKTOBER 2019 | LUNDS UNIVERSITET Omställningar Omställningar. Ordet väcker tankar om genom- gripande förändringar. I Svenska Akademiens Ordbok, vars redaktion vi har glädjen att ha just här i Lund, kan vi spåra en rad historiska använd- ningar av och associationer till ordet. Man kan omställa pjäserna på ett schackbräde, vilket för tankarna till strategier oc
https://www.lu.se/sites/www.lu.se/files/framtidsveckan_2019_program_final_190923.pdf - 2026-05-07
Short- and long-time diffusion and dynamic scaling in suspensions of charged colloidal particles
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Treatment Preferences for Acute Allergic Reactions : A Discrete Choice Experiment
Background: Timely treatment of acute allergic reactions (AARs) is important to minimize reaction severity. Corticosteroid tablets dissolved in water are commonly used in mainstay treatment. A new oral film that dissolves on the tongue provides a faster and less cumbersome alternative to tablets for corticosteroid administration during AARs. This study evaluated patients' preferences for attribute
Maria Tsalkitzidou - Institutionen för experimentell medicinsk vetenskap
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R ED . JO H A N N A B ER G Q V IST R Y D ÉN O C H M A R IA LA R SSO N O m sam verkan, m ångfald och m ellanm änskliga m öten 9 78 91 88 47 39 74 Avdelningen för högskolepedagogisk utveckling Institutionen för utbildningsvetenskap Lunds Universitet. ISBN 978-91-88473-97-4 Om samverkan, mångfald och mellanmänskliga möten Proceedings från Lunds Universitets Pedagogiska Utvecklingskonferens 2017 RED.
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Exploring variation in binding of Protein A and Protein G to immunoglobulin type G by isothermal titration calorimetry
A comparison of different orthogonal techniques for the investigation of the conformational stability of NIST mAb in liquid formulations
Antikroppar har ett brett användningsområde med stor potential men det är svårt att skapa stabila lösningar. Den strukturella stabiliteten är en viktig faktor när man väljer läkemedelskandidater, och i de tidiga utvecklingsstadierna görs prediktiva undersökningar för att ta reda på varje kandidats stabilitet och utvecklings-potential. Därmed är det av största intresse att utvärdera hur antikropparA great challenge during early development of medicinal antibodies is to determine the stability of the candidates. This is required to be able to select the candidates with the greatest developability. The stability of the candidates can be estimated using different orthogonal techniques and the aim of this investigation was thus to use orthogonal techniques for the investigation of conformationa
Inhibition of coxsackie B virus infection by soluble forms of its receptors: Binding affinities, altered particle formation, and competition with cellular receptors
We previously reported that soluble decay-accelerating factor (DAF) and coxsackievirus-adenovirus receptor (CAR) blocked coxsackievirus 133 (CVB3) myocarditis in mice, but only soluble CAR blocked CVB3-mediated pancreatitis. Here, we report that the in vitro mechanisms of viral inhibition by these soluble receptors also differ. Soluble DAF inhibited virus infection through the formation of reversi
