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C4b-binding protein (C4BP) is best known as a potent soluble inhibitor of the classical and lectin pathways of the complement system. This large 500kDa multimeric plasma glycoprotein is expressed mainly in the liver but also in lung and pancreas. It consists of several identical 75kDa α-chains and often also one 40kDa β-chain, both of which are mainly composed of complement control protein (CCP) d
Ögonrörelserna påverkade hos f.d. barncancerpatienter – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Ögonrörelserna påverkade hos f.d. barncancerpatienter 2016-02-18 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Foto: Dreamstime Merpar
https://www.vetenskaphalsa.se/ogonrorelserna-paverkade-hos-f-d-barncancerpatienter/ - 2026-07-12
Vector navigation, i.e., maintaining a constant heading for a given amount of time, is hypothesized to provide a viable basis for the navigational feats of a number of long-distance animal migrants. Since animals following this strategy are subject to drift by wind or by ocean current, performing long migrations relying on vector navigation is particularly challenging. We tested whether vector nav
Estimation of high-resolution terrestrial evapotranspiration (ET) from Landsat data is important in many climatic, hydrologic, and agricultural applications, as it can help bridging the gap between existing coarse-resolution ET products and point-based field measurements. However, there is large uncertainty among existing ET products from Landsat that limit their application. This study presents a
Neural stem cells (NSCs) derived from human fetal striatum and transplanted as neurospheres survive in stroke-damaged striatum, migrate from the implantation site, and differentiate into mature neurons. Here, we investigated how various steps of neurogenesis are affected by intrastriatal transplantation of human NSCs at different time points after stroke and with different numbers of cells in each
AIM: Injections administered by patients are one of the mainstays of diabetes management. Proper injection technique is vital to avoiding intramuscular injections, ensuring appropriate delivery to the subcutaneous tissues and avoiding common complications such as lipohypertrophy. Yet few formal guidelines have been published summarizing all that is known about best practice. We propose new injecti
The Paleocene-Eocene Thermal Maximum (PETM, ca. 56 Ma) is marked by a negative carbon isotope excursion (CIE) and increased global temperatures. The CIE is thought to result from the release of 13C-depleted carbon, although the source(s) of carbon and triggers for its release, its rate of release, and the mechanisms by which the Earth system recovered are all debated. Many of the proposed mechanis
Prostate-specific antigen (PSA) is a serine protease secreted by hath normal prostate glandular celts and prostate cancer cells. The major proteolytic substrates for PSA are the gel-forming proteins in semen, semenogelin (Sg) I and II. On the basis of the PSA cleavage map for Sg I and II, a series of small peptides (ie., ≤ 7 amino acids) was synthesized and coupled at the COOH terminus to 7-amino-
Reliable quantitative vegetation reconstructions for Europe during the Holocene are crucial to improving our understanding of landscape dynamics, making it possible to assess the past effects of environmental variables and land-use change on ecosystems and biodiversity, and mitigating their effects in the future. We present here the most spatially extensive and temporally continuous pollen-based r
Insects contribute considerably to global crop pollination, with pollination deficits being documented for multiple entomophilous or pollinator-dependent crops. Different cultivars of crops are being cultivated within and across production regions, so it is essential to understand the cultivar variability of pollination deficits. Here, we used a dataset from 286 sites from multiple production regi
Nitrogenase is the only enzyme that can cleave the strong triple bond in N2, making nitrogen available for biological life. There are three isozymes of nitrogenase, differing in the composition of the active site, viz., Mo, V, and Fe-nitrogenase. Recently, the first crystal structure of Fe-nitrogenase was presented. We have performed the first combined quantum mechanical and molecular mechanical (
Human dihydroorotate dehydrogenase (DHODH) catalyzes the fourth step of the de novo pyrimidine biosynthesis pathway and uses ubiquinone Q10, a lipophilic molecule located in the inner mitochondrial membrane (IMM), as its co-substrate. DHODH is anchored to the IMM by a single transmembrane helix located at its N-terminus. Nevertheless, how DHODH function is determined by its surrounding membrane en
Background: One of the preanalytical factors that can affect the results of arterial blood gas (ABG) analysis is the time from sample collection to analysis. A delay in analysis may affect the results due to factors such as ongoing cellular metabolism within the blood sample, gas exchange between the blood sample and the environment, and temperature changes. ABG analysis can be delayed for various
Microsoft Word - Thesis of Ruth Oettle The Environment for sale? The examination of the critical features of a third‐party in facilitating a transaction in the market for environmental offsets. Ruth Oettle ruth.oettle@gmail.com 25 May 2008 Submitted in partial fulfilment of the requirements for the International Master’s Programme in Environmental Studies and Sustainability Science (LUMES), Lund U
https://www.lumes.lu.se/sites/lumes.lu.se/files/oettle_ruth.pdf - 2026-07-15
Traditionellt produceras trähus högst i två våningar p.g.a. historiskt svårkontrollerade brän-der. Idag är byggtekniken utvecklad och det är tillåtet att bygga trähus i flera våningar. Andel trähus som byggs med prefabricerade delar ökar idag i Sverige. Genom att producera montagefärdiga element i varierande storlek förflyttas husproduktionen från byggarbetsplats till fabrik. Syftet med studien äTraditionally, wooden houses are produced with a maximum of two floors, due to historical difficulties to control fires. Today, construction technology is developed so far that it is con-sidered safe to build wooden houses with additional floors. The percentage of wooden houses built with prefabricated parts is increasing in Sweden today. By producing module elements in various sizes, house produc
Popular Abstract in Swedish Paternalism i allmänläkarens vardag - om läkarens makt och patientens rätt till självbestämmande. I mitt vardagliga arbete som allmänläkare möter jag patienter med olika symtom och sjukdomar. Hur bör allmänläkaren förhålla sig till en patient som ställer krav på en åtgärd – en speciell undersökning, ett recept på en viss medicin eller ett intyg – som läkaren inte finneThe overall aim of this thesis was to identify and analyse situations raising the question of possible paternalism in everyday general practice in Sweden. Both questionnaires to a random sample of respondents and interviews have been used. The ethical awareness among GPs in Sweden and the variety of ethical issues, suggest that medical ethics is a subject of high relevance in general practice. Th
Popular Abstract in Undetermined 1971 förklarade president Richard Nixon, som så många amerikanska presidenter före honom, krig. Nixons fiende var dock något oortodox; Nixon förklarade krig mot cancer. I och med att senaten godkände ”National Cancer Act”, av pressen snabbt döpt till ”War on cancer”, hoppades Nixon att kunna utradera cancer med hjälp av kraftigt ökade anslag till cancerforskning koDespite recent advances in cancer treatment, truly innovative approaches are required to move beyond the modest benefits achieved to date. HAMLET is a human protein-lipid complex originally discovered in breast milk able to kill a wide range of tumour cells while leaving healthy, differentiated cells unaffected. The aim of this thesis was to identify mechanisms dictating HAMLET sensitivity and to
Popular Abstract in Swedish Proteiner I varje cell i kroppen finns en kopia av vårt DNA. DNA är uppdelat i en massa gener som vart och ett innehåller en karta för uppbyggnaden av ett protein. Dessa proteiner kontrollerar nästan alla aspekter av det vi kallar liv. De transporterar syre, bygger upp vävnad, extraherar energi ur den föda vi stoppar i oss och bygger upp alla molekyler som behövs för våThis thesis deals with Ca2+ binding to proteins, electrostatic interactions in and between proteins as well as inter- and intramolecular interactions. A computer program was developed to determine Ca2+ binding constants from experimental titration data of proteins. We further studied the effect of deamidation in the Ca2+ binding site of Calbindin D9k on the Ca2+ binding and cooperativity and concl
Popular Abstract in Swedish Nematod-fångande svampar är en grupp av filamentösa svampar som lever i jorden. De kan som deras namn antyder fånga och infektera nematoder. Varför är det då viktigt att studera dessa svampar? Svaret är just nematoder. Nematoder, även kända som rundmaskar, kan infektera både människor, djur och växter. Vi i Europa är relativt förskonade mot dessa infektioner om man jämfNematode-trapping fungi are soil-living organisms with the unique ability to capture and infect free-living nematodes. The interest in studying these fungi arises from their potential use as biological control agents for plant- and animal-parasitic nematodes. To enter the parasitic stage, nematode-trapping fungi develop different kinds of trapping structures. In order to understand more about the
Hälso- och sjukvårdspersonal har varit en av de yrkesgrupper som först fick vaccinera sig mot covid-19. Smittspridningen inom yrkesgruppen har dock fortsatt varit stor. För att minska smittspridning och trygga patientsäkerheten har regioner i Sverige infört vaccinationskrav för hälso- och sjukvårdspersonal. Med stöd av den rättsdogmatiska metoden utreder uppsatsen följderna beslutet att inte vacciHealthcare professionals have been one of the first occupational groups that got vaccinated against covid-19. Nevertheless, the spread of infection within the occupational group have continued to be high. To reduce the spread of infection and to safeguard patient safety regions in Sweden have introduced vaccine mandates towards its healthcare professionals. With support from the legal dogmatic met
