Search results

Calculation - estimating the costs of a project Guidance 9/11/24 Guidance "Full cost estimate for funding application" is to be enclosed with the application. It is not compulsory to use this calculation, which is intended to provide support in estimating the costs of a project. General information about the calculation - The formulas in the calculation are not protected. - The starting year can b

https://www.cec.lu.se/sites/cec.lu.se/files/2025-01/Calculation%20for%20external%20funding%202025%20eng%20CEC.xlsx - 2026-07-09

Professor Contact details Email: valentin [dot] jeutner [at] jur [dot] lu [dot] se Phone: +46 46 222 11 18Organisation Department of Law Room number: 504 Service point: 56 WebpageValentin Jeutners profile in Lund University research portalOther affiliations Researcher Human Rights Law Profile area member LU Profile Area: Human rights Researcher Public International Law Associate professor Departme

https://www.law.lu.se/valentin-jeutner - 2026-07-08

Professor Contact details Email: valentin [dot] jeutner [at] jur [dot] lu [dot] se Phone: +46 46 222 11 18Organisation Department of Law Room number: 504 Service point: 56 WebpageValentin Jeutners profile in Lund University research portalOther affiliations Researcher Human Rights Law Profile area member LU Profile Area: Human rights Researcher Public International Law Associate professor Departme

https://www.humanrights.lu.se/valentin-jeutner - 2026-07-08

Purpose: In addition to genomic signaling, it is accepted that estrogen receptor-alpha (ER alpha) has nonnuclear signaling functions, which correlate with tamoxifen resistance in preclinical models. However, evidence for cytoplasmic ER localization in human breast tumors is less established. We sought to determine the presence and implications of nonnuclear ER in clinical specimens. Experimental D

Objectives: To investigate absolute and relative risk of serious infections in adult/elderly inflammatory bowel disease (IBD) diagnosed 2002–2017. Methods: Nationwide, register-based cohort study of Swedish patients with IBD compared with general population matched reference individuals with regard to time to first serious infection, equal to hospital admission. Multivariable Cox regression estima

Background: We have previously identified a locus on human chromosome 20q13.1, encompassing related genes of postulated WFDC-type protease inhibitors and semen coagulum proteins. Three of the genes with WFDC motif also coded for the Kunitz-type protease inhibitor motif. In this report, we have reinvestigated the locus for homologous genes encoding Kunitz motif only. The identified genes have been

Aortic valve stenosis and, atherosclerotic disease have several risk factors in common, in particular, hypercholesterolemia. Histologically, the diseased valves appear to have areas of inflammation much like atherosclerotic plaques. The effect of lipid-lowering therapy on the progression of aortic stenosis (AS) is unclear, and there are no randomized treatment trials evaluating cardiovascular morb

The genetic causes of familial breast cancer are still unclear, where only less than 20% have evident germline mutations. Most studies focus on mutations that cause a direct impact in the protein, disregarding the synonymous variants, where the codon is changed but the amino acid encoded remains the same. Synonymous variants can affect mRNA stability and translation, by differences in codon usage

Head and neck skin cancer surgery using a full thickness skin graft is a common procedure. Evidence concerning the effects of perioperative antithrombotic treatment on complications is limited. The aim of this study was to evaluate whether perioperative antithrombotic treatment is associated with risk of necrosis, bleeding or infection after full thickness skin graft surgery. Retrospective single-

PURPOSEAPR-246 (PRIMA-1MET) is a novel drug that restores transcriptional activity of unfolded wild-type or mutant p53. The main aims of this first-in-human trial were to determine maximum-tolerated dose (MTD), safety, dose-limiting toxicities (DLTs), and pharmacokinetics (PK) of APR-246. PATIENTS AND METHODSAPR-246 was administered as a 2-hour intravenous infusion once per day for 4 consecutive d

Background Medication abortion, with a combination of mifepristone and misoprostol, is highly effective and safe. However, there is insufficient evidence on efficacy and safety at very early gestations before a pregnancy can be visualized with ultrasonography. Methods We conducted a multicenter, noninferiority, randomized, controlled trial involving women requesting medication abortion at up to 42

Mitochondrial dysfunction is associated with pathogenic mitochondrial (mt)DNA mutations. The majority of mtDNA point mutations have a heteroplasmic status, which is defined as the coexistence of wild-type and mutated DNA within a cell or tissue. Previous findings demonstrated that certain mtDNA heteroplasmic mutations contribute to widely spread chronic diseases, including cancer, and alterations