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Objectives: Randomized controlled trials are currently conducted to assess whether the mortality from prostate cancer is reduced by early detection with the use of prostate-specific antigen (PSA) measurements in serum. To be effective, such a program should be able to reduce the absolute number of men diagnosed with metastatic prostate cancer (for which no cure is available). The aim of the presen
Background No data exist regarding mortality rate in young patients with a first-time anterior shoulder dislocation. A cohort of 255 patients aged 1240 years had a primary anterior shoulder dislocation during the years 1978 and 1979. After 10 years, 9 of the patients had died-which is a high figure for this cohort of patients. The question thus arose as to whether these patients had an increased m
Objective: To develop evidence based recommendations for the management of hip osteoarthritis (OA). Methods: The multidisciplinary guideline development group comprised 18 rheumatologists, 4 orthopaedic surgeons, and 1 epidemiologist, representing 14 European countries. Each participant contributed up to 10 propositions describing key clinical aspects of hip OA management. Ten final recommendation
Äldre anställdas ställning på arbetsmarknaden är onekligen osäker. I detta arbete försöker jag att räta ut och förstå hur äldre arbetstagare är skyddade på arbetsmarknaden genom att undersöka hur gällande rätt är designat. Detta görs genom en komparativ studie mellan Sverige och Kina, där en rad olika undersökningsområden kopplat till anställningsskydd för äldre bearbetas. Arbetet berör och förklaThe status of the elderly on the labour market is undeniably precarious. In this thesis, I am trying to straighten out how the elderly are protected on the labour market and how the legislation to protect them is designed. This is done through a comparative study between Sweden and China, where a number of research areas associated with employment protection for elderly are processed. I am, in thi
The energy sector in the world today is in the middle of a huge challenge regarding grid development and power production. Whilst a significant part of the world's population are struggling without access to electricity, the more developed part of the world is trying to replace existing energy sources into renewable ones, and are also facing the challenge of an aging grid which is in desperate
The invention of the integrated circuit is a key milestone in the history of electronic circuits. Since its introduction the number of components on a chip have increased rapidly, making them more powerful and able to perform complex operations, but it has also changed the design process. Today different parts of a chip can be developed separately as Intellectual Property (IP) and then put togethe
Post-ischemic inflammation plays an important role in the evolution of brain injury, recovery and repair after stroke. Housing rodents in an enriched environment provides multisensory stimulation to the brain and enhances functional recovery after experimental stroke, also depressing the release of cytokines and chemokines in the peri-infarct. In order to identify targets for late stroke treatment
The heat transferred to the turbine blade is substantially increased as the turbine inlet temperature is increased. Improved cooling methods are therefore needed for the turbine blades to ensure a long durability and safe operation. The blade tip region is exposed to very hot gas flow, and suffers high local thermal loads due to the external tip leakage flow. A common way to cool the tip is to des
Background: Nordic Lymphoma Group has conducted a phase ll trial in primary central nervous system lymphoma patients applying age-adjusted multi-agent immunochemotherapy regimen, which in elderly patients included temozolomide maintenance treatment. Design and Methods: Patients with newly diagnosed PCNSL aged 18-75 years were eligible. Sixty-six patients (median age 64 years) were enrolled. Two ag
Some dietary factors could be involved as cofactors in cervical carcinogenesis, but evidence is inconclusive. There are no data about the effect of fruits and vegetables intake (F&V) on cervical cancer from cohort studies. We examined the association between the intake of F&V and selected nutrients and the incidence of carcinoma in situ (CIS) and invasive squamous cervical cancer (ISC) in
Fibroblast growth factor-8 (FGF-8) is implicated in the development and progression of breast cancer and its levels are frequently elevated in breast tumors. The mechanisms driving FGF-8-mediated tumorigenesis are not well understood. Herein we aimed to identify target genes associated with FGF-8b-mediated breast cancer cell proliferation by carrying out a cDNA microarray analysis of genes express
The Sao Francisco Craton (SFC) is an Archaean craton that hosts a significant number of mafic intrusions. Previous attempts to date the igneous emplacement of these rocks are limited to a few dates of poor precision. Here, two dyke swarms from the Uaua Block in the northeastern portion of the craton were dated using U-Pb on baddeleyite (ID-TIMS) and zircon (SIMS). The older dyke swarm trends mainl
INTRODUCTION: We have shown that low protein C levels predict poor survival up to five years in a general intensive care unit patient material and hypothesize that treatment with protein C is beneficial. The objectives were to calculate costs of protein C treatment, at best-case scenario, per statistical life saved. MATERIALS AND METHODS: Ninety-two patients with deranged global haemostatic tests
The literature dealing with abdominal wall surgery is often flawed due to lack of adherence to accepted reporting standards and statistical methodology. The EuraHS Working Group (European Registry of Abdominal Wall Hernias) organised a consensus meeting of surgical experts and researchers with an interest in abdominal wall surgery, including a statistician, the editors of the journal Hernia and sc
På senare år har korruption i internationella affärstransaktioner blivit till ett växande problem. Den internationella viljan att förebygga korruption har ökat i takt med att kunskapen om korruptionens skadliga verkningar blivit större. Detta har resulterat i en rad mellanstatliga instrument som Sverige anslutit sig till. Instrumenten ålägger medlemsstaterna att enskilt inrätta effektiva system ge
Teknisk innovation inom den finansiella sektorn och inom elektronisk han- del har växt dom senaste åren. Detta har bidragit till att nuvarande betal- ningsmarknad erbjuder allt fler digitala betalmetoder för enskilda- och juri- diska personer. En utav dessa betalmetoder är Bitcoin. Bitcoin fick sitt ge- nomslag efter finanskrisen 2009 och har sedan dess lockat användare värl- den över. Bitcoin är Technical innovation within the financial sector and electronic commerce has grown in recent years. This has contributed to the current payment mar- ket offering an increasing number of digital payment methods for individu- als and legal entities. One of these payment methods is Bitcoin. Bitcoin gai- ned prominence after the 2009 financial crisis and has since attracted users worldwide. Bitcoin is
Under de senaste åren har en rad plattformsföretag etablerat sig inom olika sektorer av samhället och vid det här laget är de flesta människor bekanta med företag som Foodora och Uber. Uppkomsten och den starka etableringen av gig-ekonomin har skapat en hel del oklarheter vad gäller arbetsrättsliga frågor. Gig-ekonomin bygger på en treparts-relation mellan tjänsteleverantören, användaren/kunden ocIn recent years, a number of platform companies have established themselves in various sectors of society and by now most people are familiar with companies such as Foodora and Uber. The rise and the big establishment of the gig economy has created a lot of uncertainty regarding labor law issues. The gig economy is based on a tripartite relationship between the service provider, the user/customer
Cities around the world are leading the race toward an environmentally sustainable future, but one of their major obstacles have been the personal automobile. The movement of people using public transportation often has a far lower impact than the personal automobile, but these systems are often rigid and expensive to build and operator. Now, with the emergence of intelligent transport systems – a
While many crystals, both natural and artificial, grow isotropically, there are examples of crystals growing anisotropically. The aim of this theoretical study was to confirm the growth modes displayed by three different crystals, representing 3D, 2D and 1D structures. This was done by using energetic calculations with both molecular mechanics, with ReaxFF$_{ \textrm {SiO}}$ as the force field, an
Popular Abstract in Swedish En industrirobot är en flexibel programmerbar maskin som bör användas för sådant arbete som inte lämpar sig för människan att utföra. Olika tekniska begränsningar i dagens styrsystem begränsar dock robotars tillämpbarhet. Avhandlingen föreslår ett nytt sätt att bygga upp robotstyrsystem så att roboten på bästa sätt skall kunna tjäna människan.Industrial robots play a key role in manufacturing systems. Robots are distinguished from other types of machinery mainly on the basis of their programmability and ability to be adaptable to different tasks. The use of computer control to achieve desired flexibility implies that software issues for embedded control systems are central for the applicability and utilization of the equipment. The str
