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Purpose: Guidelines recommend targeting mean arterial pressure (MAP) > 65 mmHg in patients after cardiac arrest (CA). Recent trials have studied the effects of targeting a higher MAP as compared to a lower MAP after CA. We performed a systematic review and individual patient data meta-analysis to investigate the effects of higher versus lower MAP targets on patient outcome. Method: We searched the

Small cell lung cancer (SCLC) is characterized by rapid growth and high metastatic capacity. It has strong epidemiologic and biologic links to tobacco carcinogens. Although the majority of SCLCs exhibit neuroendocrine features, an important subset of tumors lacks these properties. Genomic profiling of SCLC reveals genetic instability, almost universal inactivation of the tumor suppressor genes TP5

There is increased awareness of palliative care needs in people with COPD or interstitial lung disease (ILD). This European Respiratory Society (ERS) task force aimed to provide recommendations for initiation and integration of palliative care into the respiratory care of adult people with COPD or ILD. The ERS task force consisted of 20 members, including representatives of people with COPD or ILD

Diagnosing sepsis in critical care remains a challenge due to the lack of gold-standard diagnostics. Calprotectin (S100A8/A9) has been proposed as a diagnostic marker to identify sepsis in critically ill patients. This study evaluated the diagnostic performance of calprotectin and C-reactive protein (CRP) to distinguish between sepsis and non-sepsis on intensive care unit (ICU) admission. Admissio

An important area of application of robotics technologies is unmanned water surface and underwater vehicles, such as in remote exploration work, maritime transportation, repairs of oil rigs and so on. This study evaluates the consequences of these technologies, particularly in a liability context. Taking into account the characteristics of vehicles mentioned above, especially autonomy, it is expec

The European Resuscitation Council (ERC) and the European Society of Intensive Care Medicine (ESICM) have collaborated to produce these post-resuscitation care guidelines for adults, which are based on the International Consensus on Cardiopulmonary Resuscitation Science with Treatment Recommendations (CoSTR) pubished by the International Liaison Committee on Resuscitation (ILCOR). The topics cover

Second cancers were studied among 68,104 cases of colorectal cancer (CRC) from the Swedish Family-Cancer Database. A total of 1,113 patients received a diagnosis of second CRC; 25 of them had a family history of CRC. Cases of second CRC with a family history were diagnosed up to 10 years before sporadic cases. The relative risk (RR) of all second CRCs was 2.21 compared with the first CRC. Familial

Neurotrophic factors are candidates for treating epilepsy, but their development has been hampered by difficulties in achieving stable and targeted delivery of efficacious concentrations within the desired brain region. We have developed an encapsulated cell technology that overcomes these obstacles by providing a targeted, continuous, de novo synthesized source of high levels of neurotrophic mole

Aim: Previous studies evaluating the relationship between sex and post-resuscitation care and outcomes following out-of-hospital cardiac arrest (OHCA) are conflicting. We investigated the association between sex and outcomes as well as neurodiagnostic testing in a prospective multicenter international registry of patients admitted to intensive care units following OHCA. Methods: OHCA survivors enr

Aim: To determine the ability of serum glial fibrillary acidic protein (GFAp) and tau protein to predict neurological outcome after out-of-hospital cardiac arrest (OHCA). Methods: We measured plasma concentrations of GFAp and tau of patients included in the previously published COMACARE trial (NCT02698917) on intensive care unit admission and at 24, 48, and 72 h after OHCA, and compared them to ne

OBJECTIVE: Previous literature has suggested that identifying putative differences in health care seeking patterns before death by suicide depending on age and gender may facilitate more targeted suicide preventive approaches. The aim of this study is to map health care utilisation among individuals in the two years prior to suicide in Sweden in 2015 and to examine possible age and gender differen

The purpose of this study is to investigate the prediction of Ki-67 expression of breast cancers using MRI parameters from ultrafast (UF) DCE-MRI, DWI, T2WI, and the lesion size. Breast MRI was performed with a 3T scanner using dedicated breast coils. UF DCE-MRI was obtained using Compressed Sensing-VIBE (prototype sequence). As a kinetic parameter of UF DCE-MRI, maximum slope (MS) was defined as

Background: Cardiac arrest (CA) represents the third leading cause of death worldwide. Among patients resuscitated and admitted to hospital, death and severe neurological sequelae are frequent but difficult to predict. Blood biomarkers offer clinicians the potential to improve prognostication. Previous studies suggest that circulating non-coding RNAs constitute a reservoir of novel biomarkers. The

Following the idea originally proposed during the ESO-Workshop The Very Large Telescope in 2030, the concept of a high resolution spectrograph for the VLT has been further explored, both for the science and technological aspects. Such an instrument will fill a gap in capabilities amongst the landscape of future instrumentation planned for the next decade. Its key characteristic will be high spectr

Agriculture is key to sustainable development globally – particularly incountries where agriculture both accounts for most of the land use andprovides a livelihood for most of the population. We map out a collaborativeresearch agenda aimed at tackling the urgent but poorly understood issue ofthe role of farmer organisations in overcoming political barriers tosustainable and inclusive agricultural

AI-kommissionen föreslår 75 steg för att Sverige ska stärkas genom AI. Många av förslagen är välriktade, inte minst på utbildnings- och forskningsområdet. Det krävs tunga AI-investeringar framöver, men de får inte bara rikta in sig på teknik skriver bland annat Virginia Dignum, Professor Responsible Artificial Intelligence Umeå Universitet, Jonas Ivarsson, professor i informatik vid Göteborgs uni

INTRODUCTION ASSESSING THE SUSTAINABILITY OF FORESTRY IN THE BASQUE COUNTRY: Effects of Management Practices on Soil Conditions in Pinus radiata Plantations Thesis submitted in fulfilment of the requirements of LUMES, Master of Environmental Science, Lund University, Sweden by Irantzu Lexartza Artza R.M.Azkue Kalea, 1-3.Ezk. Basauri, 48970 Bizkaia irantzu@euskalerria.org Supervisor: Patrik Wallman

https://www.lumes.lu.se/sites/lumes.lu.se/files/irantzu_lexartza.pdf - 2026-07-25