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Osteoarthritis is a chronic degenerative joint disease, and a rapidly growing cause of musculoskeletal disability, chronic pain, and reduced quality of life in an ageing European population. Our aims are to gain novel insights into osteoarthritis - its etiology, occurrence, natural history, treatments, prediction, disease monitoring, and disease burden - to allow for better care, decision making,
Life Cycle Assessment (LCA) studies are valuable tools for identifying high impact processes and redesigning supply chains. However, LCAs have limits, in the sense that they offer insight into relative sustainability and don't question whether a product, or its use, is sustainable in absolute terms. In this intentionally provocative paper, you join Emma, a fictional average American 15-year-old, a
This paper uses data from an observational study, conducted at access points in straight sections of primary roads in Malaysia in 2012, to investigate the effects of motorcyclists' behavior and road environment attributes on the occurrence of serious traffic conflicts involving motorcyclists entering primary roads via access points. In order to handle the unobserved heterogeneity in the small samp
Designing technologies that clothe, adorn, or are otherwise placed on the body raises questions concerning the role they will play in dressing ourselves. We situate self-fashioning - or the process through which we stylise and present our bodies - as a complex practice where a series of social, material, and contextual factors shape how we present ourselves. Informed by reflective discussions and
In an interconnected world, climate change impacts can cascade across sectors and regions, creating systemic risks. Here we analyse cascading climate change impacts on the EU, originating from outside the region, and identify critical intervention points for adaptation. Using network analysis, we integrate stakeholder-co-produced impact chains with quantitative data for 102 countries across foreig
Forskargruppen bedriver forskning och utbildning på forskarnivå inom aktivt och hälsosamt åldrande. Vi medverkar i flera av Medicinska fakultetens utbildningsprogram på grundnivå och avancerad nivå, samt gör utbildningsinsatser vid tekniska (LTH) respektive samhällsvetenskapliga fakulteten. Här arbetar forskare och lärare från flera discipliner och professioner - arbetsterapi, fysioterapi, omvårdnThe group consists of about 25 senior and junior researchers, PhD students and technical and administrative staff. We represent many different disciplines and professions - gerontology, occupational therapy, physiotherapy, nursing, public health, sociology, psychology and epidemiology. Many of the employees are licensed health care professionals. The research group is the core of the interdiscipl
Anhedoni, minskad motivation att uppleva lust, är associerad med förändringar i belöningssystemet. Belägen i ventrala striatum utgör den bilaterala nucleus accumbens (NAcc) den centrala noden i detta nätverk, där dopamin agerar som huvudsaklig excitatorisk neurotransmitter. Studier med funktionell magnetresonanstomografi (fMRI) har visat att aktiviteten i ventrala striatum minskar under belöningsbAnhedonia, reduced motivation to experience pleasure, is associated with alterations in the circuitry of the reward system. Located in the ventral striatum, the bilateral nucleus accumbens (NAcc) is the central hub of this network where dopamine acts as the main excitatory neurotransmitter. Studies using functional magnetic resonance imaging (fMRI) found that activity in the ventral striatum is de
Objective: Data remain divergent regarding the activational effects of endogenous hormones on adult cognitive function. We examined the association between cognition, hormones and androgen receptor (AR) CAG repeat length in a large cohort of men. Design: Community-based, cross-sectional study of 3369 men aged 40-79 years. Methods: Cognition tests were the Rey-Osterrieth Complex Figure, Camden Topo
Binding energy shifts between atomic and solid states have been observed with improved accuracy for All 4f and Ag 3d core levels applying a simultaneous measurement method. Also the 3d photoelectron spectrum and binding energies of free Ag atoms have been observed for the first time. New values determined as free atom to bulk solid shifts deviate considerably from previous estimate for Au but agre
In this review, we analyze several types of graphene-based sensors for glucose detection with respect to their preparation, properties and efficiency in electro-chemical processes. Graphene may display different types of defects, which play a role in the electron transfer processes. Oxygenated groups on the edges of graphene planes reduce the graphene in-plane conductivity, but may enhance the het
After the latest Permian mass extinction event, microbial mats filled the ecological niche previously occupied by metazoan reefs, resulting in widespread microbialites. This study focuses on the lipid biomarker (molecular fossil) and invertebrate fossil records from Neotethyan platform margin sections to understand microbial-metazoan bioherm formation. Here, we find that early Griesbachian thrombo
In this episode, PhD researcher Federica Catonini speaks to Professor Vito De Lucia from the Norwegian Centre for the Law of the Sea about the relationship between the BBNJ Agreement and climate change. They address topics such as the relevance of the BBNJ for climate change, ocean carbon sinks conservation, ocean carbon dioxide removal, the potential issues and tensions between biodiversity conse
Premise: Many animals provide ecosystem services in the form of pollination including honeybees, which have become globally dominant floral visitors. A rich literature documents considerable variation in single visit pollination effectiveness, but this literature has yet to be extensively synthesized to address whether honeybees are effective pollinators. Methods: We conducted a hierarchical meta-
Responsible internationalization is a term increasingly used to promote relationship building in a world shaped by the growing impact of global challenges and geopolitical competition. In these changing global conditions, researchers and universities have learned that they need to adhere to an expanded set of research norms. Today these norms include aspects well known to researchers, such as rese
This work demonstrates the utility of dual-arm robots with dual-wrist force-torque sensors in manipulating a Deformable Linear Object (DLO) within an unknown environment that imposes constraints on the DLO’s movement through contacts and fixtures. We propose a strategy to estimate the pose of unknown environmental contacts encountered during the manipulation of a DLO, classifying the induced const
Vår forskning är inriktad på epilepsi och att förstå de patologiska förändringarna som sker i hjärnan före och efter epileptiska anfall. Cirka 0.7 % av befolkningen har epilepsi och för mer än 30 % av dem finns idag ingen medicin som hjälper. Vi är speciellt intresserade av det immunologiska svaret i hjärnan och hur det kan moduleras vid epilepsi. Nyligen var vi de första i världen att beskriva Our research is focused on epilepsy and the pathophysiological changes that may occur in the brain before and after epileptic seizures. About 0,7 % of the community has epilepsy and more than 30 % are resistant to any known medical therapy. We have a particular interest in the immune reaction in the brain and how it can be modulated in epilepsy. Recently, we were the first to describe an immune r
