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Background: Carry Life UF is a novel peritoneal dialysis (PD) technology for improved fluid management using steady concentration PD (SCPD). The Carry Life UF treatment starts with a manual peritoneal fill of 1.36% glucose PD fluid, followed by a 5-hour treatment where small amounts of glucose are continuously added to maintain a stable intraperitoneal glucose concentration. A recent in-center cli
Introduction Parkinson’s disease (PD) is a common neurodegenerative disease, which has extensive pathology that critically includes the loss of midbrain dopaminergic neurons. This loss leads to debilitating motor features such as bradykinesia and rigidity, as well as some non-motor symptoms. Intracerebral dopamine cell transplants have been explored for many years as a new approach to treating PD
Hepatitis A virus (HAV) remains a preventable cause of acute viral hepatitis, with an estimated 159 million new infections and 39 000 deaths in 2019. Although improved care and hygiene reduced deaths, global incidence rose by approximately 4%, driven by increased symptomatic cases and population growth. The availability of safe and highly immunogenic vaccines and the absence of chronic carriage ma
A search is presented for new particles produced in proton-proton collisions at a centre-of-mass energy of 13 TeV that result in final states comprising a massive vector (W or Z) boson that decays hadronically and large missing transverse momentum. The data sample was collected with the ATLAS experiment at the Large Hadron Collider from 2015 to 2018 and corresponds to an integrated luminosity of 1
A search for a new heavy boson produced via gluon-fusion in the four-lepton channel with missing transverse momentum or jets is performed. The search uses proton-proton collision data equivalent to an integrated luminosity of 139 fb−1 at a centre-of-mass energy of 13 TeV collected by the ATLAS detector between 2015 and 2018 at the Large Hadron Collider. This study explores the decays of heavy boso
A search for pair production of vector-like quarks, both up-type (T) and down-type (B), as well as for four-top-quark production, is presented. The search is based on pp collisions at TeV recorded in 2012 with the ATLAS detector at the CERN Large Hadron Collider and corresponding to an integrated luminosity of 20.3 fb(-1). Data are analysed in the lepton-plus-jets final state, characterised by an
The results of a search for top squark (stop) pair production in final states with one isolated lepton, jets, and missing transverse momentum are reported. The analysis is performed with proton-proton collision data at root s = 8 TeV collected with the ATLAS detector at the LHC in 2012 corresponding to an integrated luminosity of 20 fb(-1). The lightest supersymmetric particle (LSP) is taken to be
Tapasin is a subunit of the transporter associated with antigen processing (TAP). It associates with the major histocompatibility complex (MHC) class I. We show that tapasin interacts with beta- and gamma-subunits of COPI coatomer. COPI retrieves membrane proteins from the Golgi network back to the endoplasmic reticulum (ER). The COPI subunit-associated tapasin also interacts with MHC class I mole
In this study healthy never-smoking subjects (n = 18) were recruited from a population study. Bronchoalveolar lavage (BAL), blood lymphocytes and bronchial biopsies, analysed both in the epithelium and lamina propria, were stained for T and B lymphocytes, natural killer (NK) cells and different subpopulations of T lymphocytes. In BAL, significantly higher proportions of T lymphocytes (CD3), T lymp
Popular Abstract in Swedish Avhandlingen handlar om lungornas funktion hos för tidigt födda (prematura) barn med brist på surfaktant, ett ämne som normalt ska finnas i lungorna, och hur lungfunktionen hos sådana barn kan förbättras genom tillförsel av det saknade ämnet utifrån. I avhandlingen har också använts en djurmodell (för tidigt födda lamm) för att studera hur konstgjord andning vid födelseThe thesis investigates lung function and the effects of rescue surfactant treatment in mechanically ventilated preterm human infants with respiratory distress syndrome (RDS), and the effects of ventilation at birth on the response to surfactant supplementation in preterm lambs. To assess lung function, the author recorded static pressure-volume (P-V) curves during passive deflation from total lun
OBJECTIVE: To study the possibility of improving blood lipids, glucose tolerance and insulin sensitivity in women with impaired glucose tolerance and a history of gestational diabetes by merely changing the glycaemic index (GI) and dietary fibre (DF) content of their bread. DESIGN: Randomized crossover study where test subjects were given either low GI/high DF or high GI/low DF bread products duri
We present a new algorithm to calculate the near-field distribution of scattered light of multiple nanospheres based on recursive order-of-scattering (OS) and the matrix inversion approaches, which avoids the divergent problem encountered in origin OS method at the resonance condition. Using this method, we investigate the light-transport properties of linear chains of Ag nanospheres. We found a m
Abstract - Vol. I In this Volume of the thesis, which consists of two volumes, a risk analysis framework for application in the maritime transport system of packaged dangerous goods (PDG) is presented. In many countries, dangerous goods risks have been ranked high among public concerns. Such concerns are mainly due to the increasing volume of dangerous goods, human safety and health and environme
The formation name Almelund Shale is proposed for a lithostratigraphically defined unit to replace the outdated chronostratigraphical designations Upper Didymograptus Shale and Dicellograptus Shale in the Middle and lowermost Upper Ordovician succession in Scania. The Almelund Shale is a lithologically uniform unit of dark-grey to black shales with rare carbonate interbeds between the Komstad Lime
BACKGROUND: The role of sleeping problems in the causal pathway between job strain and musculoskeletal pain is not clear. Purpose: To investigate the impact of sleeping problems and job strain on the one-year risk for neck, shoulder, and lumbar pain. METHOD: A prospective study, using self-administered questionnaires, of a healthy cohort of 4,140 vocationally active persons ages 45-64, residing in
This thesis explores the effects of institutional arrangements for innovation in clusters. Clusters have become one of the most popular concepts in innovation policy studies in recent years. They have been ascribed as places with structures that reduce transaction costs, and enable innovation processes due to the prevalence of different types of externalities. The focus of this dissertation is on
Sweden is a country that traditionally respects the freedom of association and the large number of existing trade unions confirms this statement.On the other hand, however, the Swedish trade union system is structured in a way that eliminates almost every sort of competition between different organizations. In fact, for every sector of the economy there is approximately one union for blue collars
