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Background-beta-Adrenergic stimulation is the main trigger for cardiac events in type 1 long-QT syndrome (LQT1). We evaluated a possible association between ion channel response to beta-adrenergic stimulation and clinical response to beta-blocker therapy according to mutation location. Methods and Results-The study sample comprised 860 patients with genetically confirmed mutations in the KCNQ1 cha
Background: Medical treatment of hypertension is not always sufficient to achieve blood pressure control. Despite this, previous studies on supplementary therapies, such as yoga, are relatively few. We investigated the effects of two yoga interventions on blood pressure and quality of life in patients in primary health care diagnosed with hypertension. Methods: Adult patients (age 20-80 years) wit
In this work the inhomogeneous (zero-phonon line) and homogeneous linewidths and the permanent electric dipole moment change (averaged value of all dipole orientations) for the Ce 4f-5d transition in Y2SiO5 were measured in order to investigate the possibility for using Ce as a sensor to detect the hyperfine state of a spatially close-lying Pr or Eu ion. The experiments were carried out on Ce dope
I januari 2008 trädde två nya lagar ikraft i Sverige. Lagen (2007:978) om hemlig rumsavlyssning gav de brottsbekämpande myndigheterna rätten att använda en ny metod, rumsavlyssning för att utreda redan begångna brott och lagen (2007:979) om åtgärder för att förhindra vissa särskilt allvarliga brott introducerade en möjlighet för myndigheterna att använda hemliga tvångsmedel som teleavlyssning, telIn January 2008 two new legislations entered into force in Sweden. The law (2007:978) on bugging gave the crime fighting authorities the right to use a new method, bugging, to investigate already committed crimes and the law (2007:979) on measures to prevent particularly serious crimes introduced a possibility for the authorities to use secret surveillance as telephone tapping, wire monitoring, fi
This thesis addresses the complexities of the situation of the Roma in Romania and Spain and the challenges of including isolated groups in society. The main texts used for comparison come from the Council of Europe’s expert bodies: the European Commission Against Racism and Intolerance (ECRI), the Advisory Committee (ACFC) under the Framework Convention for the Protection of National Minorities (
This thesis aims to investigate the dynamics of the so-called “leverage-effect”. This asymmetry in volatility after negative shocks, relative to positive shocks has been documented extensively before. However, except for findings that it is not due to leverage, the underlying or enhancing factors that cause it have not been investigated. This thesis aims to do so, by testing for the influence of f
According to Chapter 2 Section 2 of the Swedish Tort Liability Act, pure economic loss arising in non-contractual relations shall be compensated if the tortfeasor has caused the loss through the commission of a crime. Although never intended, until recently, the general view was that in the absence of legislation, damages could only be awarded for pure economic loss outside contractual relations i
Many extensions of the Standard Model posit the existence of heavy particles with long lifetimes. In this Letter, results are presented of a search for events containing one or more such particles, which decay at a significant distance from their production point, using a final state containing charged hadrons and an associated muon. This analysis uses a data sample of proton-proton collisions at
ObjectiveTo assess the role of the placental arterial Doppler examination at 23-24 gestational weeks for predicting adverse perinatal outcome in high-risk pregnancies. DesignRetrospective register study. SettingSkane University Hospital in Malmo. PopulationSix hundred and forty-five women with high-risk pregnancies, without fetal malformations or chromosomal abnormalities. MethodsPlacental (uterin
Since the elections of 2010 there are 14 per cent women in the Colombian congress - a remarkably low number in comparison with several other countries in Latin America where quotas of allocation are common. Decades of armed conflict might give a hint of why gender progress has been slow in Colombia, but at the same time as stereotyped gender roles are highly dominating, women are in no sense passi
There are laws that prohibit ships from discharging solid waste into the Mediterranean Sea. However, it’s estimated that between 15-35% of all plastic found in the Mediterranean comes from merchant shipping. Economic incentives are important to make ships reduce their maritime litter, and this essay will assess economic policies to prevent further pollution. France and Spain have different systems
The purpose with the government proposal, En skärpt sexualbrottslagstiftning (prop. 2012/13:111), is to correct certain shortcomings in the Swedish rape law (6 kap 1 § 2 st BrB) and thereby reinforce and increase the protection of sexual integrity and the right of self-determination. The essay examines the regulation of rape cases, particulary when the victim reacts with passivity. The government
Background In the surroundings of the Dadaab Refugee Camps in Kenya lives a large pastoral population under less favourable conditions than the people inside the refugee camps. Many international NGO’s have started to support the hosting community, but there seems to be a lack of long term oriented development work. This project is based on a wonder over why it apparently is difficult for an inter
We report results of detailed empirical valence bond simulations that model the effect of several amino acid substitutions on the thermodynamic (ΔG°) and kinetic activation (ΔG⧧) barriers to deprotonation of dihydroxyacetone phosphate (DHAP) and d-glyceraldehyde 3-phosphate (GAP) bound to wild-type triosephosphate isomerase (TIM), as well as to the K12G, E97A, E97D, E97Q, K12G/E97A, I170A, L230A,
Gambling disorder is associated with severe financial, social, and psychological consequences, but treatment-seeking rates have been described to be low. Apart from formal treatment, motivational interventions in nontreatment-seeking high-risk gamblers have been shown to be promising. However, little is known about the effectiveness and acceptability of such motivational interventions carried out
Background: The increased prevalence of atopic diseases may be due to lifestyle changes affecting our exposure to microbes. We investigated the association between infections, fever, and atopic diseases in a large international birth cohort setting. Methods: 3842 children at genetic risk for type 1 diabetes were followed prospectively for the first 10 years for the occurrence of infections and ato
[3H]Arachidonic (20:4) and [14C]linoleic acid (18:2) were fed to thoracic duct-cannulated rats in test meals of either tracers alone, cream, Intralipid, pure arachidonic acid, or pure linoleic acid. Less [3H]20:4 than [14C]18:2 was recovered in chyle during the first 5 h. After cream feeding, the proportion of radioactivity found in phospholipids was high and increased during the first 3 h. After [3H]Arachidonic (20:4) and [14C]linoleic acid (18:2) were fed to thoracic duct-cannulated rats in test meals of either tracers alone, cream, Intralipid, pure arachidonic acid, or pure linoleic acid. Less [3H]20:4 than [14C]18:2 was recovered in chyle during the first 5 h. After cream feeding, the proportion of radioactivity found in phospholipids was high and increased during the first 3 h. After
