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Objective. Although deep vein thrombosis (DVT) and pulmonary embolism (PE) are manifestations of the same disease, far from all patients develop PE. Our objective was to investigate risk-modifying factors. Setting, subjects and design. Between 1970 and 1982, 23 796 autopsies, representing 84% of all in-hospital deaths in the Malmo City population, were performed, using a standardized procedure. In
Palaeomagnetic and geochronological studies on mafic rocks in the Lake Ladoga region in South Russian Karelia provide a new, reliably dated Mesoproterozoic key paleopole for the East European Craton (Baltica). U-Pb dating on baddeleyite gives a crystallisation age of 1452 +/- 12 Ma for one of the studied dolerite dykes. A mean palaeomagnetic pole for the Mesoproterozoic dolerite dykes. Valaam sill
Phosphatidylinositol phosphate kinase (PIPK) is an enzyme involved in the regulation of cellular levels of phosphoinositides involved in various physiological processes, such as cytoskeletal organization, ion channel activation, and vesicle trafficking. In animals, research has focused on the modes of activation and function of PIPKs, providing an understanding of the importance of plasma membrane
Popular Abstract in English Bolivia, as with other Latin American countries, is considered to be in an epidemiological transition due to the continued persistence of infectious diseases, and nutritional deficiencies related to poverty and food insecurity, together with an increase in chronic non-communicable diseases mainly related to lifestyle factors. The work presented in this thesis was focuseThe synergistic relation between nutritional deficiency and infection may have negative effects on the immune system, making individuals more vulnerable to infection. Zinc can affect the resistance to infections by modulating cytokine release, and by acting as a cofactor of thymulin, which induces the differentiation of immature T lymphocytes. To investigate the modulation of the immune response b
Objectives: To examine whether the mix of community and institutional long-term care (ILTC) for people with dementia (PwD) in Europe could be improved; assess the economic consequences of providing alternative services for particular groups of ILTC entrants and explore the transnational application of the ‘Balance of Care’ (BoC) approach. Method: A BoC study was undertaken in Estonia, Finland, Fra
Background: There is an urgent need to improve patient safety in the area of medication treatment among the elderly. The aim of this study was to explore which improvement needs and strengths, relating to medication safety, arise from a multi-professional intervention in primary care and further to describe and follow up on the agreements for change that were established within the intervention. M
ABSTRACTAs a part of a democratic demand for transparency in urban development processes it is important that design professionals hold the ability to scrutinise their own work process, and at certain stages let go of predefined ideas of future realities. This work revolves around how design professionals perceive options for design in such situations. A basic assumption in this work is that a des
IntroductionGovernment and public agencies in Sweden have promoted the expansion of eHealth. The strategy behind many of the eHealth services is to increase quality of care, enhance efficiency, patient empowerment and patient safety. Patient online access to their electronic health record (EHR) is one of the most important civic eHealth services. By 2017, all patients in Sweden will be able to acc
While there is general agreement on the necessity tomeasure glomerular filtration rate (GFR) inmany clinical situations, there is less agreement on the bestmethod to achieve this purpose. As the gold standardmethod for GFR determination, urinary (or renal) clearance of inulin, fades into the background due to inconvenience and high cost, a diversity of filtrationmarkers and protocols compete to re
A reliable assessment of glomerular filtration rate (GFR) is of paramount importance in clinical practice as well as epidemiological and clinical research settings. It is recommended by Kidney Disease: Improving Global Outcomes guidelines in specific populations (anorectic, cirrhotic, obese, renal and non-renal transplant patients) where estimation equations are unreliable. Measured GFR is the onl
A 2-year-old boy underwent an uneventful transanal endorectal pull-through for Hirschsprung's disease. Postoperatively he suffered from pneumaturia which prompted surgical evaluation. He was found to have a rectum to seminal vesicle fistula. He was re-operated closing the fistula through an anterior transperineal approach with a successful operative outcome.
Online market makers bring together two or more distinct different parties to interact and transact with each other. By doing this, they either reduce search costs, shared transaction costs, or both. Reducing search costs reduces asymmetric information among users and makes sampling of candidates easier. Reducing shared transaction costs means making the transaction more flexible, less costly, and
The purpose of this study is to evaluate what impact the conflict in Afghanistan has had on the democratization process in the country. Almost twenty years have passed since the US-led invasion and the overthrow of the authoritarian Taliban regime in a response to the 9/11 attacks on American soil. The goal with the invasion was not only to catch Usama bin Ladin, but also to replace the religious
Background-beta-Adrenergic stimulation is the main trigger for cardiac events in type 1 long-QT syndrome (LQT1). We evaluated a possible association between ion channel response to beta-adrenergic stimulation and clinical response to beta-blocker therapy according to mutation location. Methods and Results-The study sample comprised 860 patients with genetically confirmed mutations in the KCNQ1 cha
The lack of accountability for human rights violations arising out of the activities of multinational enterprises has been identified as a key impediment to the fulfillment of universal human rights and the corresponding access to remedy for victims. However, the last couple of years have witnessed an increasing movement to bridge the accountability gap on the national and international level. Th
Loss of biodiversity is an immediate threat to the planet and if no actions are taken it is expected to accelerate. The highest species richness on smaller scale is found in semi-natural temperate grasslands, with one of the documented records from Stora Alvaret on Öland, Sweden. The area is protected under the Natura 2000-network and Länstyrelsen Kalmar are responsible for monitoring while local
Based on the extensive criticism surrounding the victimization of women in the women, peace and security agenda discourse, this essay seeks to analyze the discourse after the adaption of resolution 2122, a widely recognized step in the direction to focus more on women’s participation. The aim of the study is thus to analyze the discourse around women’s participation and agency on a global and nati
Reindeer husbandry has long been a central element of the traditional livelihood and culture of indigenous Sami people in northern Sweden. However, it faces several challenges from competing land uses, primarily forestry. Different forest conditions are desired by forestry and reindeer husbandry to accommodate each sectors’ distinct interests, promoting high timber and pulp production or improved
This thesis is concerned with history within Nick Clegg’s and Nigel Farage’s political discourse during the six months leading up to the 2016 referendum on the United Kingdom’s membership in the European Union. Using Thematic Analysis combined with Klas-Göran Karlsson’s typology of the use of history, Jörn Rüsen’s typology of historical narrative and drawing on the theoretical framework of histori
