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The Wilms tumor gene (WT1) encodes a zinc-finger containing transcription factor present in primitive hematopoietic progenitor cells. WT1 is also highly expressed in most cases of acute myeloid leukemia. Moreover, WT1 can interfere with induced differentiation of leukemic cell lines. These data suggest a function of WT1 in the maintenance of a primitive phenotype and a role in leukemogenesis by in

Denna rapport är författad inom pilotprojektet ”Maritima risker i Öresundsområdet” (Sundrisk) där projektets avsikt var att genomföra en integrerad riskanalys av maritima risker i Öresundsområdet. En serie rapporter från olika discipliner har författats inom pilotprojektet. Målsättningen med delprojektet som presenteras i denna rapport var att identifiera och belysa brister i organisation och män

Central to the sustainable production and consumption (SCP) agenda is the need for radical changes not only in the ways we produce but also in the ways we consume. The SCP agenda emerged within the understanding that it is not possible to reach the necessary reductions in environmental impact and resource consumption purely by technical solutions directed at improving the efficiency of production

Popular Abstract in Swedish Den här avhandlingen behandlar hur fettdroppar i mjölk slås sönder i en mjölkhomogenisator. Mekanismerna bakom sönderslagningen har analyserats genom uppmätning av flödesfältet i spalten samt genom att fotografera dropparna, när de slås sönder. För att möjliggöra mätning och fotografering har två skalmodeller av en homogenisator tagits fram. En fullskalemodell, vilken The overall aim of this project was to investigate the drop break-up process in milk homogenisers. This was done by measurements and calculations of the flow fields in the gap region and by visualisation of drops being broken up. To make visualisation and measurements possible, two scale models of a homogeniser gap were developed. The full-scale model was a direct copy of the gap in a production-

Popular Abstract in Swedish Avhandlingen består av en introduktion och följande artiklar: Artikel I: Using resultants for SAGBI basis verification in the univariate polynomial ring. Författare: Anna Torstensson, Victor Ufnarovski och Hans Öfverbeck. Sammanfattning: En resultant-identitet för polynom i en variabel bevisas och används för att karakterisera SAGBI-baser för underalgebror genereradeThe thesis consists of an introduction and the following four papers: Paper I: Using resultants for SAGBI basis verification in the univariate polynomial ring. Authors: Anna Torstensson, Victor Ufnarovski and Hans Öfverbeck. Abstract: A resultant-type identity for univariate polynomials is proved and used to characterise SAGBI bases of subalgebras generated by two polynomials. A new equivalent

The infrastructure for the third generation of mobile telephony, UMTS, is under construction in Sweden. Within three years four operators were to build competing systems to cover 99,98 % of the population. The case of the 3G infrastructure illustrates how the sustainability issues are handled in planning and environmental management, with conflicting goals between institutional levels and compet

The article presents an analysis of boundary work within the context of care for the elderly, where violence appears to be widespread though still relatively unacknowledged. By resorting to certain descriptive – often jocular – modes, the staff designate aggressive acts committed by patients as 'non-violent'. This occurs although intent, responsibility, and injury – all common criteria associated

Popular Abstract in Swedish Senare forskning har påvisat att beslutsfattare som återger attraktivitets skattningar (aspekter) av egenskaper (attribut) av det valda och det icke valda alternativet i ett beslut som de tidigare fattat, ökar attraktivitets differensen mellan alternativen. Denna efterbesluts attraktivitets differentiering (konsolidering) verkar till fördel för det valda alternativet. KRecent research has shown that when decision makers in retrospect are asked to reproduce attractiveness evaluations (of aspects) of important characteristics (attributes) of a chosen and a non-chosen choice alternative, they exaggerate the attractiveness difference between the alternatives. This post-decision attractiveness differentiation (consolidation) works in favor of the chosen alternative.

Popular Abstract in Swedish Knäledsförslitning är vanligt. Ledsjukdom, med smärta och nedsatt funktion som följd, är den vanligaste kroniska sjukdomen hos äldre, vanligare än högt blodtryck, hjärtsjukdom och diabetes. Behandlingen av knäledsförslitning är fokuserad på smärtlindring. Till en början används vanligt mediciner mot smärtan, men senare i sjukdomsförloppet byts den smärtande leden ofta uThe overall purpose was to evaluate patient-relevant outcomes in patients with knee injury and post-traumatic osteoarthritis of the knee. A self-administered questionnaire, The Knee injury and Osteoarthritis Outcome Score (KOOS) was developed by literature search, consulting an expert panel (including patients referred to physical therapy because of knee-related problems, orthopedic surgeons, and

Genomic allergen rapid detection (GARD) is an in vitro assay for the prediction of skin sensitizing capacity of chemicals. The GARD assay monitors changes in the expression of 196 genes, termed the GARD prediction signature. In short, MUTZ-3 cells, representing a well-characterized in vitro model of human dendritic cells (DCs), are exposed to the test substances for 24 h. After RNA extraction and

Software-Defined Networking (SDN) is a novel architectural model for cloud network infrastructure, improving resource utilization, scalability and administration. SDN deployments increasingly rely on virtual switches executing on commodity operating systems with large code bases, which are prime targets for adversaries attacking the network infrastructure. We describe and implement TruSDN , a fram