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Sensitivity and selectivity studies in capillary electrophoresis

Popular Abstract in Swedish Vad arbetar en analytisk kemist med? Exempel på kemiska analyser är att en idrottsman ska dopingtestas eller att eventuella föroreningar i vattnet från en bäck ska bestämmas. Den analytiska kemistens problemställning är vanligtvis att identifiera (kvalitativ analys) och mäta upp (kvantitativ analys) innehållet i ett prov. Ofta är de intressanta ämneshalterna mycket lågaCapillary electrophoresis is characterised by high separation efficiency, applicability to a wide range of compounds, small sample and solvent consumption and simple instrumentation. To improve sensitivity using on-line absorbance detectors, which are hampered by the short optical path length, sample volumes in the microlitre range were concentrated to nanolitre volumes either off-line or on-line.

Fuzzy inference system for analog joystick emulation with an inductive tongue-computer interface

This paper describes the development of a fuzzy inference system (FIS) for emulating an analog joystick using an inductive tongue-computer interface. The principle of operation of the interface and the inductive sensors signals are described. The FIS receives sensor signals and output the Cartesian position of the virtual joystick, which can be used to control the mouse pointer in a personal compu

Comprehensive analysis of microRNA expression in regionalized human neural progenitor cells reveals microRNA-10 as a caudalizing factor.

MicroRNAs (miRNAs) have been implicated in regulating multiple processes during brain development in various species. However, the function of miRNAs in human brain development remains largely unexplored. Here, we provide a comprehensive analysis of miRNA expression of regionalized neural progenitor cells derived from human embryonic stem cells and human foetal brain. We found miR-92b-3p and miR-1

TP53 Mutations are infrequent in newly diagnosed chronic lymphocytic leukemia

TP53 mutations in the absence of 17p-deletion correlate with rapid disease progression and poor survival in chronic lymphocytic leukemia (CLL). Herein, we determined the TP53 mutation frequency in 268 newly diagnosed CLL patients from a population-based material. Overall, we detected TP53 mutations in 3.7% of patients (n = 10), where 7/10 cases showed a concomitant 17p-deletion, confirming the hig

Minimal Solvers for Unsynchronized TDOA Sensor Network Calibration

Calibration of network nodes using only time differences of arrival (TDOA) measurements opens up for interesting applications in wireless ad-hoc sensor networks, e.g. finding the positions of cell phones by only ambient sounds or radio. We present two novel approaches for the problem of self-calibration of network nodes using only TDOA when both receivers and transmitters are unsynchronized. We co

The importance for strategic management decision making of understanding the impact of culture on implicit professional values.

The main concern of this paper is the joint utilization of new methods of research and analysis in the study of value. 40 persons, varying from age 20 to 70 and from different professional domains were studies by the use of a three-images technique inspired by Murray´s TAT. The aim was to unveil the implicit dimensions of work related values. Three analytical methods (content analysis, lexical ana

Out-of-hospital cardiac arrest at place of residence is associated with worse outcomes in patients admitted to intensive care : a post-hoc analysis of the Targeted Temperature Management trial

BACKGROUND: The majority of out-of-hospital cardiac arrests (OHCAs) occur at place residence, which is associated with worse outcomes in unselected prehospital populations. Our aim was to investigate whether location of arrest was associated with outcome in a selected group of initial survivors admitted to intensive care.METHODS: This is a post-hoc analysis of the Targeted Temperature Management a

Association of prenatal ambient air pollution exposure with placental mitochondrial DNA copy number, telomere length and preeclampsia

Background: Studies have shown that ambient air pollution is linked to preeclampsia (PE), possibly via generation of oxidative stress in the placenta. Telomere length and mitochondrial DNA copy number (mtDNAcn) are sensitive to oxidative stress damage.Objective: To study the association between prenatal exposure to ambient nitrogen oxides (NOx, a marker for traffic-related air pollution), and PE,

Abdominal compression as motion management for stereotactic radiotherapy of ventricular tachycardia

Background and purpose: Stereotactic body radiotherapy (SBRT) has emerged as a promising treatment for patients with ventricular tachycardia (VT) who do not respond to standard treatments. However, the management of respiratory motion during treatment remains a challenge. This study aimed to investigate the effect of abdominal compression (AC) on respiratory induced motion in the heart. Materials

The genomics and evolution of inter-sexual mimicry and female-limited polymorphisms in damselflies

Sex-limited morphs can provide profound insights into the evolution and genomic architecture of complex phenotypes. Inter-sexual mimicry is one particular type of sex-limited polymorphism in which a novel morph resembles the opposite sex. While inter-sexual mimics are known in both sexes and a diverse range of animals, their evolutionary origin is poorly understood. Here, we investigated the genom

Multicomponent services for symptoms in serious respiratory illness : a systematic review and meta-analysis

Background People living with serious respiratory illness experience a high burden of symptoms. This review aimed to determine whether multicomponent services reduce symptoms in people with serious illness related to respiratory disease. Methods Electronic databases were searched to identify randomised controlled trials (RCTs) evaluating multicomponent services that enrolled patients due to sympto

The effect of graded exercise therapy on fatigue in people with serious respiratory illness : a systematic review

Background In adults with serious respiratory illness, fatigue is prevalent and under-recognised, with few treatment options. The aim of this review was to assess the impact of graded exercise therapy (GET) on fatigue in adults with serious respiratory illness. Methods Electronic databases were searched to identify randomised controlled trials (RCTs) testing GET (involving incremental increases in

Advancing personalised care in atrial fibrillation and stroke : The potential impact of AI from prevention to rehabilitation

Atrial fibrillation (AF) is a complex condition caused by various underlying pathophysiological disorders and is the most common heart arrhythmia worldwide, affecting 2 % of the European population. This prevalence increases with age, imposing significant financial, economic, and human burdens. In Europe, stroke is the second leading cause of death and the primary cause of disability, with numbers

Dispatchable Battery Swapping System with Centralized Charging and Renewable Energy Generation

The effort to electrify society has in recent years resulted in major changes in the transportation sector. Charging time remains a challenge in several applications such as transportation and heavy machinery. A proposed solution that shortens the energy replenishment time and adds flexibility in loading the grid is to battery-swapping: exchanging the depleted battery for a fully charged one. In s