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Aims: Stratifying renal damage in type 2 diabetes is challenging due to overlapping features between diabetic nephropathy (DN) and non-diabetic renal disease (NDRD). While miR-27b-3p modulates kidney fibrosis in DN through the lysine63 ubiquitination pathway, its upstream regulation and diagnostic relevance remain unclear. Methods: In a biopsy-verified cohort of 231 chronic kidney disease (CKD) pa
The vast majority of patients with pancreatic cancer present with unresectable disease and precision medicine is lagging behind. Circulating tumor DNA (ctDNA) has emerged as a promising tool, both as a proxy for tumor burden and for capturing tumor heterogeneity, but optimal gene panels and prognostic cutoffs remain to be determined. Herein, we applied ultra-deep ctDNA sequencing using a customize
Introduction Neoadjuvant therapy is the standard of care for the treatment of human epidermal growth factor receptor 2 (HER2)-positive breast cancer (BC). Studies on first-generation antibody-drug conjugates, such as trastuzumab emtansine (T-DM1), showed equal or slightly lower efficacy than chemotherapy combined with dual HER2 blockade. Trastuzumab deruxtecan (T-DXd) is a next-generation conjugat
Background: There is mounting evidence supporting the role of the microbiota in hypertension from experimental studies and population-based studies. We aimed to investigate the relationship between specific characteristics of the gut microbiome and 24-h ambulatory blood pressure measurements. Methods: The association of gut microbial species and microbial functions, determined by shotgun metagenom
Background: Paleolithic Diet Fraction (PDF) and Paleolithic Diet Score (PDS) are both measures of how closely a food intake conforms to a Paleolithic dietary pattern. PDF is calculated directly from an individual’s absolute food intake and PDS is an aggregated score based on an individual’s food intake relative to a population. Both are inversely associated with all-cause and cause-specific mortal
The complement system can be activated by three different pathways in the body. It is wanted to be able to detect deficiencies of these activation pathways and Bioporto A/S has acquired the commercial rights to a set of ELISA based assays. There is a need in these commercial assays for optimisation of dilution and wash buffers since the idea with the ELISA kit is to sell it as a “ready-to-use kit”
One of infiltration ponds used in the preliminary step for drinking water production at Vombverket in the southern part of Sweden was set for the experiment in this study. The pond was split into two sides as one side received the source water from Vomb Lake and (untreated side). For another side, the water from the same source was pre-treated by DynaSand filter and PAC before transferred into the
Type 2 diabetes mellitus (T2DM) in children and adolescents is increasing in the world and the United States of America (US). Previous research has shown that the nurse has an important role in the management of T2DM in children and adolescents but few studies has covered how the nurses perceive and experience this role. This paper aimed to describe how nurses in the US experience their role and t
Olympic legacy was previously seen as a potential burden on the host city, however an evolutionary shift has occurred whereby it can now be regarded as an instrument in wider urban policy planning. Sustainable development is a requirement set by some governments, and London 2012 aimed to use the Olympic legacy for sustainable development in the form of urban regeneration. This paper is a case stud
SYDASIEN_2_2019_SLUTLIG_low-res.pdf På flykt efter ändrade klimatet Verklighetsfabriken Vem älskar Modi? Gatuhundar Tidskrift om Indien, Pakistan, Sri Lanka, Bangladesh, Afghanistan, Nepal, Bhutan och Maldiverna #2 2019 Sydasien.se Pris: 75 SEK 2 #2 2019 n redaktör ut, två redaktörer in. Efter nio år som redaktör för Sydasien går jag nu vidare mot nya utmaningar. Jag har i perioder önskat att jag
https://www.sasnet.lu.se/sites/sasnet.lu.se/files/sydasien_2_2019_slutlig_low-res.pdf - 2026-07-23
Brevmall Postadress Avdelningen för logopedi, foniatri och audiologi, Universitetssjukhuset, 221 85 Lund Besöksadress Lasarettsgatan 21 E-post audlog@med.lu.se Internet http://www.med.lu.se/audiolgiutbildning respektive http://www.med.lu.se/logopedutbildning Programmen för audio log i - och logopedutb i ldn ingarna AUDA17 Introduktionskurs 4,5 hp LOGA16 Introduktionskurs 4,5 hp Kursansvar v 35-37:
https://www.student.med.lu.se/sites/student.med.lu.se/files/schema_loga16_introduktionskurs_2017_0.pdf - 2026-07-23
This study explores employees' experiences and management strategies during a corporate restructuring process in a small organization. The purpose is to analyze how the restructuring process impacts employees' emotional reactions, work morale, and loyalty, as well as how management has handled uncertainty and communication to support employees. The study employs a qualitative method, using
The European Union’s identity as a normative power has long been examined and contested, most famously by Ian Manners' conceptualization in his 2002 work, Normative Power Europe. This study critically reassesses the EU's proposed identity through the lens of its responses to two pivotal crises: the Syrian conflict (2012-2015) and the 2016 EU-Türkiye Refugee Deal. The research interrogates
Current automated haematology systems lack the functionality of avian blood analysis using 10x magnification, which is an important feature as it allows for faster and more cost-effective blood analysis. The problem originates from the difference in red blood cell morphology in avian blood compared to mammalian blood, as the former are nucleated. The project was divided in two objectives, finding
In this written study, I have researched video game music from the 90’s and early 2000’s to see what I can learn from the process of composing music for video games, as well as how the hardware and software capabilities of the game consoles shaped the music. First it presents my own background and relation to the subject, next it establishes what functionally separates video game music from conven
The survival of our planet is in crisis, and it is affecting society at large. People recognise companies have significantly contributed to the problem, and stakeholders expect and demand businesses to do better. Nowadays, there are strong arguments in sustainability for engaging with as many employees as possible to find novel and innovative solutions more quickly. This study investigated how a p
Introduction The care needs of cancer patients can vary greatly across the course of their serious illness. Despite national efforts to promote supportive care – early integrated palliative care – in Sweden, systemic barriers such as ambiguous terminology and stigma complicate this development. Region Skåne Serious Illness Database (RSSID) is being developed to collect large-cohort data for condu
Contemporary processes of radicalization into far-right extremism are increasingly shaped by digital, online communication environments that convey ideology through multiple communication modes, as well as aesthetic and culturally embedded forms of expression. Short-form content platforms such as TikTok enable fast production and circulation of highly engaging content that creates communicative ar
This thesis examines the extent to which relational preconditions for innovation are institutionalised within the governance framework of the third pillar of Horizon Europe. Departing from the observation that existing research on EU innovation governance has focused predominantly on funding mechanisms and regulatory instruments, the study addresses a conceptual gap: while innovation theory consis
