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Boreal forests play a crucial role in the global carbon cycle and currently act as an important carbon sink. At the same time, these forests are increasingly affected by intensive forest management and a changing disturbance regime driven by climate change. Clear-cutting has been the dominant harvesting method in managed boreal forests, while wildfire, although rare over the last century in Sweden
Integrated pest management (IPM) is an important tool for sustainable crop production. IPM includes a diversity of methods, e.g., the use of biological control agents (BCAs) for disease control or growth promotion. While there is an increasing interest in the use of BCAs, less is known about their environmental costs and benefits on wild species, such as wild crop relatives. For example, a BCA may
Boreal forests are globally important carbon (C) sinks, but strategies for maximising their climate benefit remain under debate. Major uncertainties in this discussion arise from contrasting sink-source estimates, which largely emanate from inherent limitations of standard measurement techniques to distinct spatio-temporal scales. Here, we use a spatially-nested measurement framework that integrat
Understanding the dynamics of post-fire carbon recovery is critical for managing boreal forests under climate change. This study evaluates the LPJ-GUESS-BLAZE models’ performance in simulating vegetation structure, fire emissions, and post-fire carbon dynamics at the stand scale in a boreal forest in Sweden. Combining current climate and future scenarios (SSP1–2.6, SSP5–8.5), we investigated the i
BACKGROUND: The Global Burden of Diseases, Injuries, and Risk Factors Study 2015 provides an up-to-date synthesis of the evidence for risk factor exposure and the attributable burden of disease. By providing national and subnational assessments spanning the past 25 years, this study can inform debates on the importance of addressing risks in context.METHODS: We used the comparative risk assessment
In this study, the processes behind observed new particle formation (NPF) events and subsequent organic-dominated particle growth at the Pallas Atmosphere-Ecosystem Supersite in Northern Finland are explored with the one-dimensional column trajectory model ADCHEM. The modeled sub-micron particle mass is up to ∼75 % composed of SOA formed from highly oxidized multifunctional organic molecules (HOMs
Occurring at rates up to 6-7 syllables per second, speech perception and understanding involves rapid identification of speech sounds and pre-activation of morphemes and words. Using event-related potentials (ERPs) and functional magnetic resonance imaging (fMRI), we investigated the time-course and neural sources of pre-activation of word endings as participants heard the beginning of unfolding wOccurring at rates up to 6-7 syllables per second, speech perception and understanding involves rapid identification of speech sounds and pre-activation of morphemes and words. Using event-related potentials (ERPs) and functional magnetic resonance imaging (fMRI), we investigated the time-course and neural sources of pre-activation of word endings as participants heard the beginning of unfolding w
BACKGROUND: The Global Burden of Diseases, Injuries, and Risk Factors Study 2016 (GBD 2016) provides a comprehensive assessment of risk factor exposure and attributable burden of disease. By providing estimates over a long time series, this study can monitor risk exposure trends critical to health surveillance and inform policy debates on the importance of addressing risks in context.METHODS: We u
Combination of right EGR rates with turbocharging has been identified as a promising way to increase the maximum load and efficiency of heavy duty spark-ignited natural gas engines. With stoichiometric conditions a three way catalyst can be used which means that regulated emissions can be kept at very low levels. However dilution limit is limited in these types of engines because of the lower burnCombination of right EGR rates with turbocharging has been identified as a promising way to increase the maximum load and efficiency of heavy duty spark-ignited natural gas engines. With stoichiometric conditions a three way catalyst can be used which means that regulated emissions can be kept at very low levels. However dilution limit is limited in these types of engines because of the lower burn
Mantle cell lymphoma (MCL) is associated with poor prognosis due to an aggressive clinical course. Being a raredisease, there are few randomized trials in MCL and there is no defined golden standard in primary treatment.This works aimed to (I) investigate outcome in relation to primary treatment in MCL based on population-basedregistry data, (II) to evaluate tolerability and efficacy of lenalidomiMantle cell lymphoma (MCL) is associated with poor prognosis due to an aggressive clinical course. Being a rare disease, there are few randomized trials in MCL and there is no defined golden standard in primary treatment. This works aimed to (I) investigate outcome in relation to primary treatment in MCL based on population-based registry data, (II) to evaluate tolerability and efficacy of lenalid
From Treatment First to Housing First: What does it mean for the Social Worker?In Sweden social work with homeless people is dominated by “Treatment First” (or the staircase model). The Treatment First models weak results in combating homelessness has increased the interest for Housing First. In 2015 we started a participatory design-oriented research project in the City of Helsingborg in Sweden tIn Sweden social work with homeless people is dominated by “Treatment First” (or the staircase model). The Treatment First models weak results in combating homelessness has increased the interest for Housing First. In 2015 we started a participatory design-oriented research project in the City of Helsingborg in Sweden that aims to implement principles of Housing First in a social housing programme
Despite recent improvement in adjuvant therapies, triple-negative, and ER+ subtypes of breast cancer (BC) with metastatic potentials remain the leading cause of BC-related deaths. We investigated the role of phosphatidylinositol-4-phosphate 5-kinase alpha (PIP5Kα), a key upstream factor of PI3K/AKT, and the therapeutic effect of PIP5Kα inhibitor on subtypes of BC. The clinical importance of PIP5K1Despite recent improvement in adjuvant therapies, triple-negative, and ER+ subtypes of breast cancer (BC) with metastatic potentials remain the leading cause of BC-related deaths. We investigated the role of phosphatidylinositol-4-phosphate 5-kinase alpha (PIP5Kα), a key upstream factor of PI3K/AKT, and the therapeutic effect of PIP5Kα inhibitor on subtypes of BC. The clinical importance of PIP5K1
The aim was to evaluate an early prototype of a personalised home lighting system comprising body-worn loggers, a mobile phone, and LED-based lighting with variable intensity and colour temperature. A convenience sample (N = 28, 50% female) wore the devices for 24 hours in the field and were given a demonstration of the lighting system components in a full-scale model of a studio apartment. Partic
Importance: Prognostication of neurologic outcome after cardiac arrest is an important but challenging aspect of patient therapy management in critical care units. Objective: To determine whether serum neurofilament light chain (NFL) levels can be used for prognostication of neurologic outcome after cardiac arrest. Design, Setting and Participants: Prospective clinical biobank study of data from t
AbstractObjectives It is unclear how home environmental factors influence relocation decisions. We examined whether indoor accessibility, entrance accessibility, bathroom safety features, housing type, and housing condition were associated with relocations either within the community or to residential care facilities.MethodsWe used prospective data over 4 years from the nationally representative NObjectivesIt is unclear how home environmental factors influence relocation decisions. We examined whether indoor accessibility, entrance accessibility, bathroom safety features, housing type, and housing condition were associated with relocations either within the community or to residential care facilities.MethodsWe used prospective data over 4 years from the nationally representative National H
To satisfy customers’ desires with a maintained efficiency of the production process is a challenge for many house construction companies. Houses are one-off projects with a production process characterized by variability and complexity that often lead to unpredicted costs. Prefabricated component solutions could possibly solve these issues through modularization, mass customization and delayed pr
The use of antibodies as capture molecules in assays is a common practice. By either printing monoclonal single chain fragment variables (scFvs) on a solid support – recombinant antibody microarray – or attaching them to magnetic beads – Global Proteome Survey (GPS) – we can specifically capture and measure target proteins of interest. Using the recombinant antibody microarray, we targetpredominanThe use of antibodies as capture molecules in assays is a common practice. By either printing monoclonal single chain fragment variables (scFvs) on a solid support – recombinant antibody microarray – or attaching them to magnetic beads – Global Proteome Survey (GPS) – we can specifically capture and measure target proteins of interest. Using the recombinant antibody microarray, we target predomina
Protein misfolding is a frequently occurring event in living cells and without the quality control, the consequences are disasterous. In this thesis, we studied protein misfolding in vitro by employing a variety of fluorophores, to either detect the highly ordered aggregates of intrinsically disordered proteins/peptides or slight misfolding of a natively folded protein. Misfolding and concurrent
The concept of vandalism is analyzed as a symbolic act. An analysis of vandalism from a situational-positivistic, or a motivational-psychological, approach hardly gives an understanding of vandalism as a meaningful individual and social act. A humanistic and cultural perspective can supply ways to understand a nonprescribed behavior such as vandalism. The original meaning of vandalism is plunderin
