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Background: Ocrelizumab is a humanized anti-CD20 antibody with increased antibody-dependent cellular cytotoxicity compared with rituximab. This phase I/II study evaluated its safety and efficacy in patients with relapsed/refractory follicular lymphoma (FL) after prior rituximab therapy. Design and methods: Forty-seven patients were treated in three dose cohorts and received eight infusions every 3

We previously reported that soluble decay-accelerating factor (DAF) and coxsackievirus-adenovirus receptor (CAR) blocked coxsackievirus 133 (CVB3) myocarditis in mice, but only soluble CAR blocked CVB3-mediated pancreatitis. Here, we report that the in vitro mechanisms of viral inhibition by these soluble receptors also differ. Soluble DAF inhibited virus infection through the formation of reversi

BIDS UTVC12 Lectures and seminars 2016. Schedule 2016-06-10 Date Time Room Theme Activity Group Teacher Module 1: Course Introduction 1/11 15:00-17:00 111 Course introduction Intro 1/1 AF Issues in contemporary development: The quest for growth and the internationalization of development 4/11 10:00-12:00 MA3 The Elusive Quest for Growth Lec 1/1 MF 9/11 13:00-15:00 111 The Elusive Quest for Growth

https://www.keg.lu.se/en/sites/keg.lu.se.en/files/utvc12_fall_20160610_1.pdf - 2026-07-06

Ultrasmooth solution-processable quasi-2D perovskite thin films are of critical importance for many optoelectronic devices. In this work, we fabricated an ultrasmooth intermediate-phase free quasi-2D (PEA)2(FA)n−1PbnBr3n+1 perovskite film by using antisolvents with different polarities and boiling points to engineer the crystallization process. The XRD patterns of the perovskite powder showed that

Ensembles of (J,K)-regular low-density parity-check convolutional (LDPCC) codes are known to be asymptotically good, in the sense that the minimum free distance grows linearly with the constraint length. In this paper, we use a protograph-based analysis of terminated LDPCC codes to obtain an upper bound on the free distance growth rate of ensembles of periodically time-varying LDPCC codes. This bo

An immunological capacitive biosensor for calpastatin was developed, optimized and applied for the analysis of meat extract samples. Anti-calpastatin antibody was immobilized on a gold electrode modified with a self-assembled monolayer of mercaptoundecanoic acid and Protein A from Staphylococcus aureus, and the obtained immunosensor was inserted as the working electrode in an electrochemical cell

The aetiology of benign prostatic hyperplasia (BPH) remains unclear. The objective of the present study was to test the insulin, oestradiol and metabolic syndrome hypotheses as promoters of BPH. The design was a risk factor analysis of BPH in which the total prostate gland volume was related to endocrine and anthropometric factors. The participants studied were 184 representative men, aged 72-76 y

Background: Free and total human kallikrein 2 (hK2) might improve the discrimination between prostate cancer and benign prostatic hyperplasia. Concentrations of hK2 are 100-fold lower than concentrations of prostate-specific antigen (PSA); therefore, an hK2 assay must have a low detection limit and good specificity. Methods: PSA- and hK2-specific monoclonal antibodies were used in solid-phase, two

In laryngectomized patients a tracheo-esophageal artificial fistula can be used to achieve air flow from the trachea to the esophagus during speech. A one-way plastic valve is often used for the fistula. A free jejunal graft between the trachea and the esophagus can also be used. To avoid aspiration the transplant is attached to the submental area giving the graft a siphon-like shape. We performed

Enzymatic hydrolysis using immobilized lipases for the production of free fatty acids and glycerol is a promising alternative to the current industrial standard. This study investigates a set of hydrolysis reactions catalysed by four different immobilization techniques to increase the knowledge on two-phase systems. The evaluation of how water purity, buffer salts, and water amount affect the reac

Denna rapport redogör över utvecklingsprocessen för ett silikonfritt, läckagetätt lock för matlådan IKEA 365+, för att undvika användandet av en silikonpackning som produkten gör idag. Drivkraften bakom projektet är att silikon är ett mycket energikrävande material att producera, samt är inte i stor skala återvinningsbart idag. Rapporten använder sig av en traditionell produktutvecklingsprocess saThis report elaborates on the development process of a silicone free, leakproof seal for the lid of the IKEA 365+ food storage platform, to alleviate the need for a silicone gasket that is used for the product today. Silicone is undesirable due to the energy intensive production and because it is not recyclable at large scale. The report uses a traditional product development process along with si

In the brain, focal ischemia results in a local region of cell death and disruption of both local and remote functional neuronal networks. Tissue reorganization following stroke can be limited by factors such as extracellular matrix (ECM) molecules that prevent neuronal growth and synaptic plasticity. The brain's ECM plays a crucial role in network formation, development, and regeneration of the c

https://www.mhm.lu.se/internt/staff - 2026-07-05