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The classical pathway of complement is crucial to the immune system, but it also contributes to inflammatory diseases when dys-regulated. Binding of the C1 complex to ligands activates the pathway by inducing autoactivation of associated C1r, after which C1r activates C1s. C1s cleaves complement component C4 and then C2 to cause full activation of the system. The interaction between C1s and C4 inv
OBJECTIVE-Sleep disorders and subjective sleep complaints have been associated with increased risk of type 2 diabetes. The evidence with respect to insulin resistance (IR) and insulin secretion in individuals without type 2 diabetes has been scarce and elusive. We examined if subjective sleep complaints and their co-occurrence were associated with IR and insulin secretion in adult women and men wi
Alzheimer's disease (AD) is strongly associated with loss of synapses. The complement system has been shown to be involved in synaptic elimination. Several studies point to an association between AD and the complement system. The purpose of this study was to examine the association of cerebrospinal fluid (CSF) levels of complement components 3 and 4 (C3 and C4, respectively), and complement recept
A large and growing body of literature has investigated the national parliaments and their involvement in the activities of the Union. However, the literature does not fully cover all the national parliaments of new Member States which joined the EU after the largest enlargement of the Union in 2004. As well, little is known about the national parliaments of Baltic Member States. This paper aims t
UPPSATSENS TITEL: Den Femte Positioneringsfällan SEMINARIEDATUM: 2013-05-28 ÄMNE/KURS: Magisteruppsats i företagsekonomi 30 högskolepoäng (ECTS), FEKN90 FÖRFATTARE: Stina Cedergren och Malin Svensson HANDLEDARE: Jens Hultman Fem nyckelord: varumärkespositionering, varumärkesidentitet, förändringsprocessen, positioneringsfällor, yngre och kvinnlig målgrupp SYFTE: Syftet med uppsatsen är att TITLE: The Fifth Position Trap SEMINAR DATE: 2013-05-28 COURSE: Master thesis in business administration, 30 credits (ECTS), FEKN90 AUTHORS: Stina Cedergren and Malin Svensson ADVISOR: Jens Hultman KEYWORDS: Brand positioning, brand identity, process of change, positioning traps, a younger and female target group. PURPOSE: The purpose of this thesis is to analyze and describe the challenges
Separatist movements are gaining ground around Europe. From south to north regional separatist movements are raising their voices. The goals of each unique movement vary, from calls for increased autonomy to demands for full independence. In Italy’s autonomous province South Tyrol the question of separatism is something that engages all of the ethnical South Tyrolean parties. The parties included
Qualitative measurements of both OH and polycyclic aromatic hydrocarbons (PAH) as well as quantitative data of soot volume fraction f(v) have been obtained in vaporized liquid fuels, with the main goal of providing experimental data for combustion models and numerical mechanism validation. Measurements were carried out in a laminar coflow burner which was designed, built and integrated with an eva
Abstract The ozone (O3) decomposition in the pre-heat zone of flames can initiate and accelerate the chain-branching reactions. In the present study, formaldehyde (CH2O) was investigated by both experiment and simulation methods in methane/air laminar premixed flames under atmospheric conditions. The formaldehyde concentration profiles in the flames were measured with CH2O-PLIF. When 4500 ppm of o
Background: National guidelines recommend that healthy pregnant women take 30 minutes or more of moderate exercise a day. Most women reduce the level of physical activity during pregnancy but only a few studies of women's experiences of physical activity during pregnancy exist. The aim of the present study was to elucidate experiences and views of leisure time physical activity during pregnancy in
Objective . To evaluate the clinical performance in a paediatric population of the Lund-Malmo creatinine-based glomerular filtration rate (GFR) prediction equations, primarily developed for adults. Material and methods . Iohexol clearance was used as the gold standard in 85 paediatric Caucasian patients (0.3-17 years; 37 F/48 M). One Lund-Malmo equation was based on age and gender (LM) and one inc
Comprehensive palliative care programs are often implemented on a community level, and to evaluate such interventions, randomization by cluster (community) may be the only feasible method. In trials randomizing individual subjects, the importance of proper concealment has been stressed, In cluster randomized trials, however, concealment of individual patient allocation is often impossible. The fol
Purpose - This paper aims to illustrate a new method to cluster consumer attribute preferences and to transform spontaneously written texts by consumers about a certain favourite food product (hamburger) into distinct preference clusters of attributes. Design/methodology/approach - A new way of finding significant clusters of consumer attribute preferences is developed by means of a new text analy
The aim of the present study was to characterize the airway effects of U46619, a stable thromboxane A2 mimetic, instilled into the trachea of guinea pigs in vivo, and to investigate the role of different mediators in these effects. The airflow obstruction was evaluated by measurement of airway insufflation pressure (P1) and plasma extravasation by quantification of Evans Blue dye (EBD) in airways.
This is the story of how a large research facility of broad European and global interest, the European Spallation Source (ESS), ended up in the small university town of Lund in Sweden. This happened in spite of the fact that a number of influential European countries were at one time or another competitors to host the facility. It is also a story about politics which attempts to illustrate how clo
During the last years, many governments have set targets for increasing the share of biofuels in the transportation sector. Understanding consumer behavior is essential in designing policies that efficiently increase the uptake of cleaner technologies. In this paper we analyze adopters and non-adopters of alternative fuel vehicles (AFVs). We use diffusion of innovation theory and the established n
Context: Offspring of women with gestational diabetes (O-GDM) or type 1 diabetes mellitus (O-T1DM) have been exposed to hyperglycemia in utero and have an increased risk of developing metabolic disease in adulthood. Design: In total, we recruited 206 adult offspring comprising the two fetal hyperglycemic groups, O-GDM and O-T1DM, and, as a control group, offspring from the background population (O
Neighbourhood offices were established in the municipal of Lund by a decision in the municipal council 1999. During following years four offices opened in the surrounding villages; Veberöd, Genarp, Södra Sandby and Dalby. By using a goal oriented model and making interviews I study whether the offices reaches the goals of more effective service, developed IT-support, a stronger local democracy and
Malmö, like many other bigger cities in Europe, faces a double undertaking when facing the challenges the future. Not only must the municipal be able to provide its citizens with welfare and a high standard of living, it must also establish a level of economic growth that allows the city to act as catalyst for the surrounding area. In order to provide the population with welfare and the economy wi
The three post-communist states - Belarus, Moldova, and Ukraine ? have gone different ways in terms of freedom and democracy since the breakdown of the Soviet Union 1991. During these years, the state and the civil society have been fundamental actors in the struggle against, and even for, authoritarianism. A strong state with great capacity in Belarus has undermined the chances for the civil soc
