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Alpha-1-microglobulin, heme-binding protein, reductase and antioxidant

Popular Abstract in Swedish Alla levande organismer består av celler som tillsammans med molekyler generellt kallade extracellulär matrix bildar en vävnad. Celler innehåller fyra huvudgrupper av byggstenar: socker, fettsyror, aminosyror och nukleotider, vilka i tur och ordning bildar kolhydrater, fetter, proteiner och nukleinsyror. I vävnaderna pågår en ständig omsättning av byggstenarna och molekThis thesis describes structural and functional studies of alpha-1-microglobulin (a1m), a 26 kDa plasma and tissue protein that is evolutionarily well-conserved and belongs to the lipocalin superfamily. The lipocalins are polypeptides of 160-190-amino acids that are folded into an 8-stranded beta-barrel forming a pocket with a hydrophobic interior. a1m carries heterogeneous yellow-brown chromophor

Prospective Study of HPV16 Viral Load and Risk of In Situ and Invasive Squamous Cervical Cancer

Background: A strong association has been shown between high viral DNA load (VL) of human papillomavirus (HPV) type 16 and risk for cervical cancer in situ (CIS). However, little data is available for the significance of VL in invasive squamous cell carcinoma (SCC). Methods: In 2 nested case-control studies among women participating in cervical screening, with a cytologically normal first smear, w

Shifting between self-governing and being governed: a qualitative study of older persons' self-determination

Background: Older persons' right to exercise self-determination in daily life is supported by several laws. Research shows that older persons' self-determination is not fully respected within the healthcare sector. In order to enable and enhance older persons' self-determination, extensive knowledge of older persons' self-determination is needed. The aim of this study was to explore experiences of

Articles on Potential Theory, Functional Analysis and Hankel Forms

Popular Abstract in Swedish Avhandlingen består av tre matematiska forskningsartiklar. Den första artikeln, Paper I, undersöker spektrala egenskaper hos Neumann-Poincare-operatorer, även kallade dubbelskiktspotentialoperatorer, för områden med låg regularitet. Operatorernas spektra har kopplingar till elektrostatiska problem, och författarens intresse inleddes i samband med en tidigare artikel sPaper I: Perfekt, K.-M. and Putinar, M., Spectral bounds for the Neumann-Poincaré operator on planar domains with corners, to appear in J. Anal. Math., (2012). The boundary double layer potential, or the Neumann-Poincaré operator, is studied on the Sobolev space of order $1/2$ along the boundary, coinciding with the space of charges giving rise to double layer potentials with finite energy in the

ADHD symptoms and maturity - a follow-up study in school children.

Abstract Aim: To test the hypothesis that there is a subgroup of children with attention deficit hyperactivity disorder (ADHD) who show a decline in ADHD-symptoms that is associated with signs of biological maturation, a phenomenon referred to as a 'maturation catch-up'. Methods: The parents of 147 children who were given an examination in grades one and two 1999-2000 that included assessment of A

Adsorption of cubic liquid crystalline nanoparticles on model membranes

The interactions of lipid based cubic liquid crystalline nanoparticles (Cubosome (R)) with surface supported model membranes constituted of dioleylphosphatidylcholine ( DOPC) have been studied in situ by use of ellipsometry, quartz crystal microbalance with dissipation monitoring and neutron reflectivity. The systems investigated were cubic phase dispersions of glycerol monooleate (GMO) stabilised

The Verijarv area, South Estonia over the last millennium: A high resolution quantitative land-cover reconstruction based on pollen and historical data

Integration of palynological proxies with annual lamina counting, C-14, Pb-210, Cs-137 and Am-241 radiometric dating, historical documents and old cadastral maps enabled reconstruction of changes in the cultural landscape resulting from extensive forest clearance, arable farming and slash-and-burn practices in South Estonia over the last millennium. Changes in land-cover were quantitatively recons

Ingen regel utan undantag? Om upphovsrättsligt skyddat material som bevisning i dispositiva tvistemål

Enligt upphovsrätten har upphovsmannen ensamrätt till sitt verk, vilket omfattar exemplarframställning såväl som tillgängliggörande för allmänheten av alstret. Ensamrätten innebär att andra inte får använda verket på ett sätt som inkräktar på ensamrätten utan rättsinnehavarens samtycke. Regelverket har orsakat juridiska oklarheter beträffande om ett nyttjande av ett alster genom att inge det till Under copyright law, the originator has the exclusive right to his or her work, which includes reproduction as well as the right of communication to the public and the right of making it available to the public. The exclusive right means that others may not use the work in a way that infringes the exclusive right without the rightholder’s consent. The framework has caused uncertainty as to whether

Perceptions of COVID-19 Policies in Thailand

This thesis seeks to uncover the Thai public perception of COVID-19 policies. These policies include lockdown, curfew and social security. Thailand is a country that has been praised by the World Health Organisation for their control over the pandemic. One might wonder what regulations were implemented, for the Thai government to be able to control it so well; and how did people respond to this? T

Production of 5-ketogluconic acid using recombinant strains of Gluconobacter oxydans

5-Keto-D-gluconic acid (5-KGA) is a valuable compound that has a wide range of applications in the chemical and food industries and is commonly used as a precursor for manufacturing tartaric acid (TA). Industrial production of 5-KGA through chemical approaches was practiced in the early 1920’s and was dropped immediately due to several drawbacks because of its complicated process that resulted in

Improving energy efficiency of existing buildings - Recommendations and approaches to consider in Poland and Kosovo

The energy issue has in recent years become a hot topic around the world. Discussions about how to reduce the greenhouse gases in a sustainable manner have been raised. Given that this is an emerging problem, and that many people lack knowledge regarding this subject, it is about time that they get the information needed to be able to contribute in some way. In general, the building sector represe

Ne bis in Idem - the Charter and ECHR, Possible affects of the latest interpretation by the ECJ of the Ne Bis in Idem principle in the Haparanda Case.

Ne bis in idem is an evolving and current topic of EU law where recent case law has affected its application. The Swedish tax system contains administrative proceedings that can result in fines that can thereafter be followed (or initiated) with a criminal offence proceeding. The ECtHR revised its view on the Ne bis in Idem in Zolothukin v Russia and concluded that the Identity of the facts was de

Långsiktiga effekter på sömnrelaterade problem och självskattad hälsa efter skiftschemaförändring: en uppföljningsstudie

Studiens syfte var att undersöka de långsiktiga hälsoeffekterna av en skiftschemaförändring i på ett industriföretag, från ett snabbt framåtroterande schema till ett långsamt bakåtroterande schema. Undersökningen bygger på en studie som gjordes 2004 i samband med denna intervention. Data samlades in med hjälp av formulär som mätte subjektiv hälsa, sömn och trötthet, behov av återhämtning, obalans The purpose of this study was to examine the long term health effects of a shift change from a fast forward-rotating to a slowly backward-rotating schedule in an industrial company. The study is a follow-up of a study that was made in 2004 when this intervention was made. Data was collected using questionnaires covering subjective health, sleep and fatigue, need for recovery, work-family interface

International protection of internally displaced persons - A field study of internal displacement and available protection in the Republic of South Sudan

This thesis examines if international law and its protection mechanisms satisfactorily address the protection needs of internally displaced persons (IDPs). At the end of 2011, around 25 million people around the world were internally displaced by armed conflict, generalized violence and human rights violations. In contrast, the number of refugees was approximately 16 million. In spite of the fact

Simulating bathymetric changes in reservoirs due to sedimentation

Currently sedimentation is one of the major issues to deal with, for professionals, as it causes continuous loss of storage and hinder the intended purposes of a dam. More research and case-specific studies are required to understand the behavior of sediment transport mechanism in order to propose remedial measures. Sakuma dam on Tenryu River in Japan is one of the largest dams in Japan and it is

Developing a warehouse optimization model for humanitarian logistics : A study with United Nations High Commissioner for Refugees (UNHCR)

In humanitarian logistics today there is a gap between the practical and theoretical methods used for facility localization. The consequence is that ad-hoc methods are frequently used, leading to non-optimal localization of facilities which in turn leads to long lead times and costs. This study aims to fill that gap by identifying the factors affecting facility localization in the humanitarian sec

The roles of information systems augmenting ecological sustainability

There is a limited amount of research regarding the use of information systems (IS) augmenting organizations ecological sustainable initiatives. While the field of Green IT somewhat has been studied, Green IS has not received the same attention in scientific research. In this report we have aimed to identify areas that are poorly, or have yet to be, augmented by IS. Thus highlighting areas where o

Ursprungs- och minoritetsrättigheter vs narkotikakonventionens integritet? : en kartläggning av kokabladets betydelse i Bolivia ur ett ursprungs- och minoritetsperspektiv

This essay aims to discuss the complicacy concerning minority and indigenous rights and its complex relation to other international law instruments. In this research I focus on the situation that occurred when the Bolivian president sent an amendment to the Secretary General concerning the withdrawal of the two articles regarding coca leaf-chewing in the Single Convention on Drugs. The member-stat

Medverkan och inflytande : om brukarnas roll i socialtjänstens kunskapsutveckling

The main purpose of this essay was to study the program "Nationellt stöd för kunskapsutveckling inom socialtjänsten" ("National support for knowledge development within the social services") from the National Board of Health and Welfare on the basis of how such a development, as represented by the program, could affect clients' possibilities to participation and influence w

Changes in IFRS - Swedish Listed Entities

We aim to clarify how Swedish listed entities experience and manage changes in IFRS and how they are adapting to new and revised standards as issued by the IASB. This thesis has an abductive approach. A qualitative method was selected as a research strategy, and semi-structured interviews were conducted in order to gather relevant information from the respondents; listed entities and auditors. The