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The role of physical activity in metabolic homeostasis before and after the onset of type 2 diabetes : an IMI DIRECT study

Aims/hypothesis: It is well established that physical activity, abdominal ectopic fat and glycaemic regulation are related but the underlying structure of these relationships is unclear. The previously proposed twin-cycle hypothesis (TC) provides a mechanistic basis for impairment in glycaemic control through the interactions of substrate availability, substrate metabolism and abdominal ectopic fa

Dynamic in-situ imaging of methane hydrate formation and self-preservation in porous media

We present the results of dynamic in-situ 3D X-ray imaging of methane hydrates microstructure during methane hydrate formation and dissociation in sand samples. Short scanning times and high resolution provided by synchrotron X-rays allowed for better understanding of water movement and different types of gas-hydrate formation. Complementing previous observations, we conclude that the process of g

On the persistence of the ether as absolute space

We analyse how the concept of the ether, playing the role of absolute space, is still present in physics. When the problem is considered in the context of classical mechanics, we show that vestiges of absolute space can be found in the standard presentation of inertial systems. We offer an alternative -- fully relational -- definition of inertial systems which not only eliminates the problem but i

Educational Policy and Discourse in Inclusion Research: A Theoretical Framework

This theoretical framework is developed for a research project regarding the specific case of the national policy process for Art and Music Schools in Sweden, a process to create national regulation for the first time in their history. The project focuses on inclusion of every child, but also specifically on inclusion of two particular groups of pupils: pupils in need of special support and refuge

High sulfate concentration enhances iron mobilization from organic soil to water

Widespread increases in iron (Fe) concentrations are contributing to ongoing browning of northern freshwaters, but the driver/s behind the trends are not known. Fe mobilization in soils is known to be controlled by redox conditions, pH, and DOC availability for complexation. Moreover, high sulfate concentrations have been suggested to constrain Fe in transition from soil to water, and declining su

A Workers’ Revolution in Sweden? Exploring Economic Growth and Distributional Change with Detailed Data on Construction Workers’ Wages, 1831–1900

The impact of the transition to modern economic growth on the distribution of income is widely debated. The experience of early industrializers like Britain and the US has informed much of the debate, lending support to the idea embedded in the models of Kuznets and Lewis that real wages of laborers tend to lag behind the growth of GDP per capita in the early stages of economic development. We exa

Hip Function 6 to 10 Months After Arthroscopic Surgery: A Cross-sectional Comparison of Subjective and Objective Hip Function, Including Performance-Based Measures, in Patients Versus Controls

Background:Little is known about hip-related function, mobility, and performance in patients after hip arthroscopic surgery (HA) during the time that return to sports can be expected.Purpose:To evaluate measures of subjective and objective hip function 6 to 10 months after HA in patients compared with healthy controls and to compare objective function in the HA group between the operated and nonop

Urban land use and land cover classification with interpretable machine learning – A case study using Sentinel-2 and auxiliary data

The European commission launch of the twin Sentinel-2 satellites provides new opportunities for land use and land cover (LULC) classification because of the readily availability of their data and their enhanced spatial, temporal and spectral resolutions. The rapid development of machine learning over the past decade led to data-driven models being at the forefront of high accuracy predictions of t

Validation of cause of death classification after heart transplantation and cause-specific life expectancy compared to the general population

Background: Post heart-transplant survival has increased, but information is lacking on specific causes of death and life expectancy. We aimed to assess cause-specific loss of life-years compared to the general population, evaluate classification for cause of death after heart transplantation, and assess validity of cause of death data from the International Society of Heart and Lung Transplant (I

Reactions to environmental changes : Place attachment predicts interest in Earth observation data

Environmental changes such as extreme weather events become increasingly noticeable worldwide. Earth observation data provide information about such changes, but little is known about citizens’ perceptions of and responses to such changes. Across three studies, we assess whether people’s place attachment on different regional levels predicts interest in earth observation data, and whether perceive

Clinically Relevant Changes for Cognitive Outcomes in Preclinical and Prodromal Cognitive Stages : Implications for Clinical Alzheimer Trials

Background and ObjectivesIdentifying a clinically meaningful change in cognitive test score is essential when using cognition as an outcome in clinical trials. This is especially relevant because clinical trials increasingly feature novel composites of cognitive tests. Our primary objective was to establish minimal clinically important differences (MCIDs) for commonly used cognitive tests, using a

Exploring patient perspectives : A qualitative inquiry into healthcare perceptions, experiences and satisfaction in Lebanon

BACKGROUND: Patient perspectives have received increasing importance within health systems over the past four decades. Measures of patient experience and satisfaction are commonly used. However, these measures do not capture all the information that is available through engaging with patients. An improved understanding of the various types of patient perspectives and the distinctions between them

Extracorporeal Membrane Oxygenation: Set-up, Indications, and Complications

Extracorporeal membrane oxygenation (ECMO) occupies an increasingly important position in the clinic for the management of cardiac and/or pulmonary failure. As a rescue therapy, ECMO can support patients following respiratory or cardiac compromise to act as a bridge to recovery, to decision, or to transplant. This chapter reviews briefly the history of ECMO implementation as well as device modes,

Vindicating Vengeance and Violence? : Exegetical Approaches to Imprecatory Psalms and their Relevance for Liturgy

Doktorsavhandling i Gamla testamentets exegetik. I avhandlingen kartläggs vilka tolkningsstrategier som är tongivande i modern kommentarlitteratur av Psaltarens s.k. 'förbannelsepsalmer,' dvs. bibeltexter som vanligen utelämnas i modernt gudstjänstliv av innehållsliga skäl då de uttrycker den bedjandes önskan om hämnd och/eller våld gentemot fiender. En översikt av den exegetiska diskursen, så somDue to their calls for vengeance and violence the so called imprecatory psalms are generally considered ethically difficult and subsequently omitted from liturgy. This becomes particularly evident in breviaries, such as the Roman Catholic Church’s Liturgy of the Hours, where both entire psalms and individual verses have been omitted. The widespread omission of lament psalms (including imprecatory

Nowcasting (Short-Term Forecasting) of COVID-19 Hospitalizations Using Syndromic Healthcare Data, Sweden, 2020

We report on local nowcasting (short-term forecasting) of coronavirus disease (COVID-19) hospitalizations based on syndromic (symptom) data recorded in regular healthcare routines in Östergötland County (population ≈465,000), Sweden, early in the pandemic, when broad laboratory testing was unavailable. Daily nowcasts were supplied to the local healthcare management based on analyses of the time la

Person-centred care and preferred outcomes in early rheumatoid arthritis — the patients’ perspective

Rheumatoid arthritis (RA) is a chronic, systemic, inflammatory joint disease that affects all aspects of life. Rheumatology care strives to achieve optimal health based on person-centred care (PCC). Effective treatment is available, but patients still experience unmet needs.Aims: The overall aim of this thesis was to explore patients' perspectives of PCC and preferred outcomes in early RA. Specifi

Now you’ve got it how are you going to use it: Innovative approaches for wheelchair training : Plenary 5, 9.00-11.00, June 21

According to the World Health Organization Wheelchair Provision Guidelines (2023) wheelchair training is a critical component of the wheelchair provision process. In fact, the guidelines ‘strongly recommend’ that training for power and manual wheelchairs needs to be provided to enable maximum use and prevent abandonment and secondary injuries. Moreover, task-specific training is particularly encouAccording to the World Health Organization Wheelchair Provision Guidelines (2023) wheelchair training is a critical component of the wheelchair provision process. In fact, the guidelines ‘strongly recommend’ that training for power and manual wheelchairs needs to be provided to enable maximum use and prevent abandonment and secondary injuries. Moreover, task-specific training is particularly encou

New types of complex motion of a simple camphor boat

We discuss the motion of a rectangular camphor boat, considering the position of a camphor pill in relation to the boat's stern as the control parameter. The boat moves because the pill releases surface active molecules that decrease the surface tension and support the motion. We introduce a new experimental system in which the boat rotates on a long arm around the axis located at the centre of a

Factors Associated With Sports Function and Psychological Readiness to Return to Sports at 12 Months After Anterior Cruciate Ligament Reconstruction : A Cross-sectional Study

Background: Sports function and psychological readiness to return to sports (RTS) are important outcomes when evaluating rehabilitation after anterior cruciate ligament reconstruction (ACLR). It is, however, unclear which specific factors contribute most to these outcomes. Purpose: To determine associations between demographic characteristics, objective measurements of physical function, patient-r

Mind the Boundaries : Neurocognitive and AI-Driven Insights into Event Perception in Audio-Described Films

A fundamental aspect of the human mind is its ability to perceive, understand, and remember life experiences, which we process as distinct and meaningful sequences of events, each with a clear beginning and end. This includes experiences from audiovisual media. However, while movies do not explicitly signal when one event ends and another begins, viewers still consistently and automatically percei