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Post Conflict Futures is an ongoing project, where displaced Syrian academics meet in Visioning Labs and a global scenario group to jointly reflect on possible future developments and to look for actionable leverage points to work proactively for sustainable transitions. The collective visioning aims to identify aspects that may be critical in strategies for sustainable post conflict reconstructio

OBJECTIVE:: Multiple systematic reviews address the effect of antihypertensive treatment in people with diabetes. Here, we summarize current systematic reviews concerning antihypertensive treatment effect at different blood pressure (BP) levels, and relative treatment effect of different antihypertensive agents. METHODS:: We searched MEDLINE, BIOSIS, DARE and CDSR during years 2005–2016. Eligibili

The electrophysiological effects of pentisomide upon the intact human heart were evaluated using programmed stimulation and recording of intracardiac monophasic action potentials (MAP) in 17 patients with various ventricular arrhythmias. After i.v. administration of pentisomide, 85-135 mg, the atrial-His interval increased by 8 +/- 12 ms (p less than 0.05) during sinus rhythm and by 13 +/- 21 ms (

The endogenous reparative capacity of the adult human brain is low, and chronic neurodegenerative disorders of the central nervous system represent one of the greatest areas of unmet clinical need in the developing world. Novel therapeutic strategies to treat them include: (i) growth factor delivery to boost endogenous repair and (ii) replacement cell therapy, including replacing dopaminergic neur

Climate governance beyond the United Nations Framework Convention on Climate Change (UNFCCC)—including countries, companies, civil society, and international organizations, forming cooperative initiatives—is increasingly framed as complementing, supporting, and even substituting the multilateral negotiations. Cooperative initiatives activating nonstate actors could help bridging the ‘ambition gap’

För ungefär 350 miljoner år sedan utvecklade de första insekterna förmågan att flyga och har sedan dess dominerat våra terrestra miljöer. Trots sina pyttesmå hjärnor och avsaknad av avancerade kontrollinstrument så lyckas flygande insekter på många vis utkonkurrera modern flygteknik. Humlor och bin kan till exempel leta upp en födokälla långt ifrån sitt bo, återvända hem igen och sedan upprepa denDespite their small brains and tiny eyes, flying insects are capable of detecting and avoiding collisions with moving obstacles, and with remarkable precision they navigate through environments of different complexity. For this thesis, I have investigated how bumblebees use the pattern of apparent image motion that is generated in their eyes as they move through the world (known as optic flow), in

Background: The changing health care environment promotes the adoption of new information technologies to connect patients and health care providers. However, individuals greatly vary in their ability to use new digital systems, and in their feelings regarding integrity and validation. Caregivers in southern Sweden plan to implement a new digital primary health care (DPHC) service, and patients’ e

Given their intrinsic features, adaptive facades are required to satisfy rigid structural performances, in addition to typical insulation, thermal and energy requirements. These include a minimum of safety and serviceability levels under ordinary design loads, durability, robustness, fire resistance, capacity to sustain severe seismic events or other natural hazards, etc. The overall design proces

Background: Neuropsychiatric symptoms (NPS) are highly prevalent in Alzheimer's disease (AD) and are associated with negative outcomes. However, NPS are currently underrecognized at the memory clinic and non-pharmacological interventions are scarcely implemented. Objective: To evaluate the effectiveness of the Describe, Investigate, Create, Evaluate (DICE) method™ to improve the care for NPS in AD

OBJECTIVES: Contrast agent (CA) relaxivities are generally not well established in vivo, and the relationship between frequency/phase shift and magnetic susceptibility might be a useful alternative for CA quantification.MATERIALS AND METHODS: Twenty volunteers (25-84 years old) were investigated using test-retest pre-bolus dynamic susceptibility-contrast (DSC) magnetic resonance imaging (MRI). The

Objective: The aim was to study whether perceived environmental barriers to outdoor mobility affect changes in sense of autonomy in participation outdoors among community-dwelling older people over a two-year period. Methods: Community-dwelling people aged 75–90 years (n = 848) in central Finland were interviewed on two occasions, face-to-face at baseline and over the telephone two years later. Pe

Objective. To assess, in a population-wide study in Iceland, the genetic contribution to hip osteoarthritis (OA) leading to total hip replacement (THR). Methods. Information from 2 population-based databases in Iceland was combined: a national registry of all THRs performed between 1972 and 1996, and a genealogy database of all available Icelandic genealogy records for the last 11 centuries. A gen

Cancer patients commonly suffer from cachexia, a syndrome in which tumors induce metabolic changes in the host that lead to massive loss in skeletal muscle mass. Using a preclinical mouse model of cancer cachexia, we tested the hypothesis that tumor inoculation causes a reduction in ATP synthesis and genome-wide aberrant expression in skeletal muscle. Mice implanted with Lewis lung carcinomas were

Previous epidemiologic studies found inconsistent associations between vegetables and fruit consumption and the risk of bladder cancer. We therefore investigated the association between vegetable and fruit consumption and the risk of bladder cancer among participants of the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Data on food consumption and complete follow-up fo

Background Up-to-date evidence about levels and trends in disease and injury incidence, prevalence, and years lived with disability (YLDs) is an essential input into global, regional, and national health policies. In the Global Burden of Disease Study 2013 (GBD 2013), we estimated these quantities for acute and chronic diseases and injuries for 188 countries between 1990 and 2013. Methods Estimate

In manipulation tasks, motion trajectories are characterized by a set of key phases (i.e., motion primitives). It is therefore important to learn the motion primitives embedded in such tasks from a complete demonstration. In this paper, we propose a core framework that autonomously segments motion trajectories to support the learning of motion primitives. For this purpose, a set of segmentation po

Currently, the majority of spent batteries are not recycled but become part of the household waste in many countries, especially in China which is the largest producer and consumer of batteries. This is due to many reasons, including the lack of governmental policies to encourage and facilitate battery return and recycling. In that context this research was designed to investigate the attitudes an

Background: In spite of considerable rice production gains over the past 50 years, Sub-Saharan Africa is becoming increasingly dependent on rice imports as demand is outpacing domestic supply. The serious economic and social strains caused by this have urged national leaders to address production deficits. The aim of this article is to analyse and discuss the drivers behind recent changes in rice

Popular Abstract in Swedish Öbiogeografi och populationsdifferentiering hos Skyros murödla Hur den fantastiska variationen som finns i naturen bildas är en fråga som länge fascinerat biologer. För mer än 150 år sedan inledde två välkända biologer, Charles Darwin och Alfred Russel Wallace, en brevväxling som skulle komma att bli startskottet för ett paradigmskifte. De hade båda fått idén om naturlIslands are cradles for new biodiversity and provide natural laboratories for the study of population divergence. In my thesis, I investigated the role of different evolutionary processes in the population divergence in the Skyros wall lizard (Podarcis gaigeae), a species where islet populations have strongly diverged morphologies. I used replicate islet populations and their respective most proxi

The International Osteoporosis Foundation (IOF) Capture the Fracture Campaign aims to support implementation of Fracture Liaison Services (FLS) throughout the world. INTRODUCTION: FLS have been shown to close the ubiquitous secondary fracture prevention care gap, ensuring that fragility fracture sufferers receive appropriate assessment and intervention to reduce future fracture risk. METHODS: Capt