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Modeling traveling calcium waves in cellular structures

We report a parametric simulation study of traveling calcium waves in two classes of cellular structures: dendrite-like processes and an idealized cell body. It is motivated by the hypothesis that calcium waves may participate in spatiotemporal sensory processing; accordingly, its objective is to elucidate the dependence of traveling wave characteristics (e.g., propagation speed and amplitude) on

Development of an eHealth Intervention in Pediatric Home Infusion Therapy : Interview Study of Needs and Preferences of Parents and Health Care Professionals

Background: With the provision of home infusion therapy in children with acute or long-term illness on the rise, eHealth technologies have the potential to bridge the transition between hospital and home. However, eHealth interventions intended to support parents in managing home infusion therapy are sparse. Gaining insight into the needs and experiences of parents and health care professionals is

Towards self-reliant robots : skill learning, failure recovery, and real-time adaptation: integrating behavior trees, reinforcement learning, and vision-language models for robust robotic autonomy

Robots operating in real-world settings must manage task variability, environmental uncertainty, and failures during execution. This thesis presents a unified framework for building self-reliant robotic systems by integrating symbolic planning, reinforcement learning, behavior trees (BTs), and vision-language models (VLMs).At the core of the approach is an interpretable policy representation based

Infant responses to direct gaze and associations to autism : A live eye-tracking study

When other people look directly towards us, we often respond by looking back at them, and such direct-gaze responses are important for establishing eye contact. Atypical eye contact is common in autism, but how and when this aspect of autism develops is not well understood. Here, we studied whether how much and how quickly infants respond to others' direct gaze is associated with autism in toddler

Application of Bioactivity Profile-Based Fingerprints for Building Machine Learning Models

The volume of high throughput screening data has considerably increased since the beginning of the automated biochemical and cell-based assays era. This information-rich data source provides tremendous repurposing opportunities for data mining. It was recently shown that biochemical or cell-based assay results can be compiled into so-called high-throughput fingerprints (HTSFPs) as a new type of de

Parents' recalled experiences of the child centred health dialogue in children with overweight: a qualitative study

Background: Because overweight and obesity are still increasing and prevention of childhood obesity is more likely to be effective when initiated in preschool children, the Child Health Service in the south of Sweden developed a structured child-centred health dialogue model targeting all 4-year-old children and their families. The aim of this study was to describe parents' recalled experiences of

Deliberating a Sustainable Welfare–Work Nexus / Auf dem Weg zu einem nachhaltigen Wohlfahrt-Arbeit-Nexus

Very few countries have managed to decouple economic growth from resource use and greenhouse gas emissions in absolute terms and at rates to meet the climate targets of the Paris Agreement. To achieve this, technological solutions would need to be combined with sufficiency-oriented policies in a postgrowth context. This paper develops policy ideas for a sustainable welfare–work nexus via citizen e

A Transition towards Digital Home Visits in Social Care and Home Health Care during the Corona Pandemic

Background: Physical meetings are favoured in social care and home health service in Sweden, both when it comes to internal meetings or home visits at citizens residence. During the pandemic, physical meetings were supposed to decrease as much as possible to avoid the virus to spread. One solution was to digitize as many meetings as possible. Transforming meetings from physical to digital is not w

Improvement of modeling plant responses to low soil moisture in JULESvn4.9 and evaluation against flux tower measurements

Drought is predicted to increase in the future due to climate change, bringing with it myriad impacts on ecosystems. Plants respond to drier soils by reducing stomatal conductance in order to conserve water and avoid hydraulic damage. Despite the importance of plant drought responses for the global carbon cycle and local and regional climate feedbacks, land surface models are unable to capture obs

Health status and psychological distress among in-hospital cardiac arrest survivors in relation to gender

Aim To describe health status and psychological distress among in-hospital cardiac arrest (IHCA) survivors in relation to gender. Methods This national register study consists of data from follow-up registration of IHCA survivors 3–6 months post cardiac arrest (CA) in Sweden. A questionnaire was sent to the survivors, including measurements of health status (EQ-5D-5L) and psychological distress (H

Combustion characteristics of well-dispersed boron submicroparticles and plasma effect

Boron is an attractive high-energy fuel additive. But it could not burn efficiently in practical systems due to its high ignition temperature and slow burning velocity. Finding methods to enhance the combustion of boron is desired. This work focused on the combustion characteristics of boron submicroparticles with and without plasma discharges in a hot environment supported by CH4/N2/O2 flat flame

A confident decision support system for interpreting electrocardiograms

Computer-aided interpretation of electrocardiograms (ECGs) is widespread but many physicians hesitate to rely on the computer, because the advice is presented without information about the confidence of the advice. The purpose of this work was to develop a method to validate the advice of a computer by estimating the error of an artificial neural network output. A total of 1249 ECGs, recorded with

On the applicability of geophysics for groundwater investigations in areas with lack of hydrogeological information. Examples from Mozambique

The work presented in this thesis has aimed to improve the knowledge about the groundwater occurrence in different geological conditions in Mozambique. The main focus in this study has been on the understanding of hydrogeological conditions in area with little background information by use of geophysical investigation. The lack of background information is a problem in many countries because the e

Analysis of sentinel node biopsy - a single-institution experience supporting the use of serial sectioning and immunohistochemistry for detection of micrometastases by comparing four different histopathological laboratory protocols.

Histopathology Analysis of sentinel node biopsy - a single-institution experience supporting the use of serial sectioning and immunohistochemistry for detection of micrometastases by comparing four different histopathological laboratory protocols Aims: Detecting micrometastases (>0.2 and ≤2 mm/>200 cells) and isolated tumour cells (ITCs; ≤0.2 mm/<200 cells) is important for staging of breast cance

Preschoolers’ Understanding of a Teachable Agent-Based Game in Early Mathematics as Reflected in their Gaze Behaviors – : an Experimental Study

This study investigated how preschool children processed and understood critical information in Magical Garden, a teachable agent-based play-&-learn game targeting early math. We analyzed 36 children’s (ages 4–6 years) real-time behavior during game-use to explore whether children: (i) processed the information meant to support number sense development; (ii) showed an understanding of the teac

Significant others of suicide attempters : Their views at the time of the acute psychiatric consultation

As part of the psychiatric assessment after a suicide attempt contact with a significant other could be of importance in order to obtain an additional view of the patient's situation, and thereby possibly broadening the basis of the assessment. The aims of this study were to investigate whether information from a significant other would be helpful in the psychiatric assessment of the patient, and

Design of kinetic models for assessment of critical aspects in bioprocess development : A case study of biohydrogen

The world faces major climate challenges and extensive efforts need to be taken to combat this issue. Replacing fossil-derived fuels and chemicals with renewables are one important step on the way. Hydrogen has a great potential as a renewable energy carrier for the transport sector and as a green chemical for the industry. Today, the production of hydrogen stems primarily from fossil resources. A

Functional procurement for innovation, welfare and the environment: A mission-oriented approach

Public procurement represents a very large share of most economies worldwide. Besides its direct purchasing power, public procurement has an enormous potential to become one of the most important mission-oriented policy instruments in the context of the Sustainable Development Goals. The paper argues that the key to achieve more innovations when pursuing public procurement is to describe problems