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The performance of a new type of X-band Weather Radar (WR) for Sweden during a pilot run is studied. Compared to the conventional C-band WRs, the X-band WR covers a smaller area but with a higher spatiotemporal resolution, making it suitable for urban hydrological applications. Rainfall estimations from different elevation angles of the radar (levels) are compared at one-minute and single-event ti
Students often use incoherent strategies in their problem solving involving force and motion, as revealed, e.g. when they are asked to draw force diagrams for amusement rides involving circular motion, whether in horizontal or vertical planes. Depending on the questions asked, assignments involving circular motion can reveal different types of more or less correct and coherent strategies used by t
The correct folding of proteins is of paramount importance for their function, and protein misfolding is believed to be the primary cause of a wide range of diseases. Protein folding has been investigated with time-averaged methods and time-resolved spectroscopy, but observing the structural dynamics of the unfolding process in real-time is challenging. Here, we demonstrate an approach to directly
Hypothesis Chitosan and sulfated oat β-glucan are materials suitable to create a prebiotic coating for targeted delivery to gastrointestinal system, using the layer by layer technology. Experiment Quartz crystal microbalance with dissipation (QCM-D), spectroscopic ellipsometry (SE) and atomic force microscopy (AFM) were used to assess the multilayer formation capacity and characterize the resultin
Play is an enigmatic behaviour, the function of which is still debated, despite more than a century of research. We discuss the evolutionary function of play behaviour, focusing on the domestic dog (Canis familiaris), a unique species due to its past domestication and current cohabitation with humans. The ultimate function of play in dogs is explored through four main theories: 1) developing motor
Background: Glioblastoma is the most common and aggressive type of primary brain tumor in adults. A key problem is the capacity of glioma cells to inactivate the body’s immune response. The complement system acts as a functional bridge between the innate and adaptive immune response. Still, the role of the complement system has almost been forgotten in glioma research. In our present study, we hyp
Transdisciplinary research and collaboration is widely acknowledged as a critical success factor for solution-oriented approaches that can tackle complex sustainability challenges, such as biodiversity loss, pollution, and climate-related hazards. In this context, city governments’ engagement in transdisciplinarity is generally seen as a key condition for societal transformation towards sustainabi
A sorption isotherm expresses the relation between ambient relative humidity (RH) and equilibrium moisture content of a material for a specific temperature. The sorption isotherm can generally be divided into a hygroscopic part covering low, medium and high RH levels, and an over-hygroscopic part close to 100% RH. For wood, the hygroscopic part is dominated by water uptake in cell walls and the ov
In order to fulfil the requirements of available energy resources, there is a great need to obtain a sustainable and environmentally friendly energy utilization using combustion processes. In order to do this, it is of utmost importance to utilize non-intrusive diagnostic techniques with high spatial and temporal resolution which can characterize the combustion process and also validate combustion
Routine endomyocardial biopsy (EMB) to detect acute cellular rejection (ACR) late (>1 year) after heart transplantation (HT) remains debated. To gain knowledge on late ACR and thereby approach this issue, we studied the incidence, predictors, and outcome of late ACR. 815 late EMBs from 183 patients transplanted 1988-2010 were retrospectively reviewed until June 30, 2012. Only 4.4% of the routine a
Aims: To assess the agreement between the Ross treadmill method and the Åstrand ergometer cycle method, and the repeatability of each method. Methodology: Twenty healthy people aged 22.5 ± 2.2 years were tested on two different days, each day with both methods with a pause of 30 min between the tests. The tests were executed in the reverse order the following test day. Major findings: There was no
Background: The rising prevalence of obesity represents an important public health issue. An assessment of its costs may be useful in providing recommendations for policy and decision makers. This systematic review aimed to assess the economic burden of obesity and to identify, measure and describe the different obesity-related diseases included in the selected studies. Methods: A systematic liter
A series of poly(arylene piperidinium)s (PAPipQs) devoid of any alkali-sensitive aryl ether bonds or benzylic sites are prepared and studied as anion exchange membranes (AEMs) for alkaline fuel cells. First, the excellent alkaline stability of the model compound 4,4-diarylpiperidinium is confirmed. Medium molecular weight poly(arylene piperidine)s are then synthesized in polycondensations of N-met
The membrane lipid glucosylceramide (GlcCer) is continuously formed and degraded. Cells express two GlcCer-degrading β-glucosidases, GBA and GBA2, located in and outside the lysosome, respectively. Here we demonstrate that through transglucosylation both GBA and GBA2 are able to catalyze in vitro the transfer of glucosyl-moieties from GlcCer to cholesterol, and vice versa. Furthermore, the natural
OBJECTIVE: The aim of this study was to investigate the effect of epidermal growth factor receptor (EGFR) blockade on cell survival and on downstream signalling pathways using the monoclonal antibody cetuximab. METHODS: We used three colon cancer cell lines, of which one was EGFR-negative, and two head and neck squamous cell carcinoma (HNSCC) lines. EGFR expression and gene copy number were measur
Background: While the work situation for nurse assistants in residential care is strenuous, they themselves often state that they are satisfied with their job. More knowledge is clearly needed of the interrelationship of variables associated with job satisfaction. This study aims to investigate job satisfaction and explore associated variables among nurse assistants working in residential care.
One of the more puzzling aspects of Kant’s political thought is his insistence on the duty to obey even oppressive rulers combined with his belief in the republic as the only rightful constitutional form. In arguing that resisting oppressive power is as wrong as seizing it, Kant seems committed to the awkward position of denouncing as unrightful any attempts made by the people to establish the onl
Abstract To study influenza virus shedding during acute infection, viral load was longitudinally measured by quantitative PCR in nasal flocked swabs from patients with seasonal H3N2 influenza at a Swedish emergency department, including both hospitalized patients and outpatients. Influenza A was detected in 65/184 patients. Sampling was repeated every 3-4 days in 45 patients, with the aim of conti
Blood coagulation involves a series of enzymatic protein complexes that assemble on the surface of anionic phospholipid. To investigate whether apolipoproteins affect coagulation reactions, they where included during the preparation of anionic phospholipid vesicles using a detergent solubilization-dialysis method. Apolipoprotein components of high-density lipoproteins, especially apolipoprotein A-
The aperiodic nature of geomagnetic field variations, both in intensity and direction, can aid in dating archaeological artefacts, volcanic rocks, and sediment records that carry a palaeomagnetic signal. The success of palaeomagnetic dating relies upon our knowledge of past field variations at specific locations. Regional archaeo- and palaeomagnetic reference curves and predictions from global geo
