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22MOD_LARSSON_PROCEEDINGS_LTH_pedagogisk_inspirationskonferens_FINAL_revised

22MOD_LARSSON_PROCEEDINGS_LTH_pedagogisk_inspirationskonferens_FINAL_revised LTH:s 12:e Pedagogiska Inspirationskonferens, 7 december 2023 Abstract—This study has been carried out as an assignment in the 2021 Readership Course (GB_S91) at LTH. The motivation for this study was to obtain a further understanding of the situation of PhD students and supervisors who operate in an interdisciplinary res

https://www.lth.se/fileadmin/cee/genombrottet/konferens2023/D3_Ba__ckstro__m_etal.pdf - 2026-05-08

Karin Schillén

Professor Contact details Email: karin [dot] schillen [at] chem [dot] lu [dot] se Phone: +46 46 222 14 39Organisation Physical Chemistry Visiting address: Naturvetarvägen 14, Lund Service point: 1 WebpageKarin Schilléns profile in Lund University research portalResearch interestsSelf-assembly and phase behavior of amphiphilic block copolymers and their applications, interactions of stimuli-respons

https://www.physchem.lu.se/karin-schillen - 2026-05-08

Nationwide study of the impact of D2 lymphadenectomy on survival after gastric cancer surgery

BACKGROUND: Gastrectomy including D2 lymphadenectomy is regarded as the standard curative treatment for advanced gastric cancer in Asia. This procedure has also been adopted gradually in the West, despite lack of support from RCTs. This study sought to investigate any advantage for long-term survival following D2 lymphadenectomy in routine gastric cancer surgery in a Western nationwide population-

Myocardial injury biomarkers at point of care for early identification of primary graft dysfunction after heart transplantation

INTRODUCTION: Primary graft dysfunction (PGD) is a leading cause of 30-day mortality following heart transplantation, and early intervention in PGD may correlate to improved survival. Our analysis aimed to determine the feasibility of measuring cardiac biomarkers from the donor heart in the early phase for use as a predictor of PGD.METHODS: Blood samples from the coronary sinus were obtained at th

Health care utilization following "digi-physical" assessment compared to physical assessment for infectious symptoms in primary care

Background: The use of chat-based digital visits (eVisits) to assess infectious symptoms in primary care is rapidly increasing. The "digi-physical" model of care uses eVisits as the first line of assessment while assuming a certain proportion of patients will inevitably need to be further assessed through urgent physical examination within 48 h. It is unclear to what extent this approach can mitig

Pre-treatment health-related quality of life parameters have prognostic impact in patients >65 years with newly diagnosed mantle cell lymphoma : The Nordic Lymphoma Group MCL4 (LENA-BERIT) experience

Mantle cell lymphoma (MCL) is a rare, often aggressive type of B-cell lymphoma with poor survival and no cure. Cancer and cancer treatment has a negative impact on health-related quality of life (HRQOL) both during active disease and in the long term, and improvement of HRQOL is a crucial objective of cancer therapy in older patients and no curative intent. Baseline HRQOL has in other lymphoma pop

Free vitamin D3 index and vitamin D-binding protein in multiple sclerosis : A presymptomatic case–control study

Background and purpose: High levels of 25-hydroxyvitamin D3 (25[OH]D3) are associated with a lower risk for multiple sclerosis (MS). The bioavailability of 25(OH)D3 is regulated by its main plasma carrier, vitamin D-binding protein (DBP). Free 25(OH)D3 can be estimated by also measuring DBP concentration. In addition, DBP has immunomodulatory functions that may independently affect MS pathogenesis

Systematic review of low-income and middle-income country perceptions of visiting surgical teams from high-income countries

Background The shortage of surgeons, anaesthesiologists and obstetricians in low-income and middle-income countries (LMICs) is occasionally bridged by foreign surgical teams from high-income countries on short-term visits. To advise on ethical guidelines for such activities, the aim of this study was to present LMIC stakeholders' perceptions of visiting surgical teams from high-income countries. M

Therapist-Supported Internet-Delivered Exposure and Response Prevention for Children and Adolescents with Tourette Syndrome : A Randomized Clinical Trial

IMPORTANCE: The availability of behavior therapy for individuals with Tourette syndrome (TS) and chronic tic disorder (CTD) is limited.OBJECTIVE: To determine the efficacy and cost-effectiveness of internet-delivered exposure and response prevention (ERP) for children and adolescents with TS or CTD.DESIGN, SETTING, AND PARTICIPANTS: This single-masked, parallel group, superiority randomized clinic

Pulse Wave Velocity Measurements by Magnetic Resonance Imaging in Neonates and Adolescents : Methodological Aspects and Their Clinical Implications

Pulse wave velocity (PWV) by cardiovascular magnetic resonance (CMR) lacks standardization. The aim of this study was to investigate methodological aspects of PWV measurements by CMR in neonates and adolescents. A computer phantom was created to validate the temporal resolution required for accurate PWV. Fifteen neonates and 71 adolescents underwent CMR with reference standard 3D angiography and p

Natural history study of factor IX deficiency with focus on treatment and complications (B-Natural)

Introduction: Haemophilia B (HB) is less well studied than haemophilia A (HA); despite similarities between the two inherited bleeding disorders, important differences remain that require further research. Aim: B-Natural is a multi-centre, prospective, observational study of HB, designed to increase understanding of clinical manifestations, treatment, quality-of-life (QoL), inhibitor development,

Genome-wide Association and Meta-analysis of Age at Onset in Parkinson Disease: Evidence from the COURAGE-PD Consortium

Background and Objectives Considerable heterogeneity exists in the literature concerning genetic determinants of the age at onset (AAO) of Parkinson disease (PD), which could be attributed to a lack of well-powered replication cohorts. The previous largest genome-wide association studies (GWAS) identified SNCA and TMEM175 loci on chromosome (Chr) 4 with a significant influence on the AAO of PD; th

Body mass index and weight gain in pregnancy and cardiovascular health in middle age : A cohort study

Objective: To examine associations between body mass index (BMI) in early pregnancy and gestational weight gain (GWG) with cardiovascular health in middle age using the ‘Life's Essential 8’ (LE8) concept of the American Heart Association (AHA). Design: Population-based cohort study. Setting: Swedish CardioPulmonary bioImage Study (SCAPIS). Population: A total of 8871 women from SCAPIS were include

Evaluation of a quality improvement intervention to reduce anastomotic leak following right colectomy (EAGLE): pragmatic, batched stepped-wedge, cluster-randomized trial in 64 countries

Background: Anastomotic leak affects 8 per cent of patients after right colectomy with a 10-fold increased risk of postoperative death. The EAGLE study aimed to develop and test whether an international, standardized quality improvement intervention could reduce anastomotic leaks.Methods: The internationally intended protocol, iteratively co-developed by a multistage Delphi process, comprised an o

Smart home technologies and features based on the perspectives of present and future older adults: Preferences, needs and solution ideas elicited in a multi-generation research circle.

Despite the anticipated benefits of smart home technology (SHT) to support older adults' engagement in meaningful activities, barriers to the adoption of SHT have been identified. While research in the field of technology is surging, research on older adults playing an active role in designing and developing SHT to enhance usability is lacking. It is important to co-develop solutions to place olde

Neuroendocrine tumours: Understanding the patient experience and improving follow-up

Neuroendocrine tumours (NETs) of the small intestine (siNET) are slow-growing malignancies often diagnosed at an advanced stage. Despite their indolent nature, patients frequently experience significant symptoms, including carcinoid syndrome (CS) with diarrhoea, which impact their health-related quality of life (HRQoL). This thesis investigates the determinants of HRQoL in siNET patients, its prog

Global brain atrophy but not hippocampal atrophy is related to type 2 diabetes

AIMS: It has been suggested that in patients with type 2 diabetes mellitus (T2DM), brain atrophy is most pronounced in the hippocampus, but this has not been investigated systematically. The present pooled analysis of three studies examined if hippocampal atrophy is more prominent than global brain atrophy in patients with T2DM relative to controls.METHODS: Data were derived from a cohort study of

Health workers’ perspectives on the quality of maternal and newborn health care around the time of childbirth : Results of the Improving MAternal Newborn carE in the EURO Region (IMAgiNE EURO) project in 12 countries of the World Health Organization European Region

BACKGROUND: Health workers' (HWs') perspectives on the quality of maternal and newborn care (QMNC) are not routinely collected. In this cross-sectional study, we aimed to document HWs' perspectives on QMNC around childbirth in 12 World Health Organization (WHO) European countries.METHODS: HWs involved in maternal/neonatal care for at least one year between March 2020 and March 2023 answered an onl

Bioinformatic studies of genetic variation at known, novel and candidate blood group loci

Access to compatible blood for transfusion is a prerequisite for modern health care. The compatibility is limited by the presence of antibodies to blood group antigens, polymorphic protein and carbohydrate structures, on the surface of the red blood cell. Blood group antigens arise from genetic variation in the genes underlying their expression. Knowledge of these genes and their variation can fac

Risk factors for adverse events within one year after atrial septal closure in children : A retrospective follow-up study

Introduction: Secundum atrial septal defect is one of the most common congenital heart defects. Previous paediatric studies have mainly addressed echocardiographic and few clinical factors among children associated with adverse events. The aim of this study was to identify neonatal and other clinical risk factors associated with adverse events up to one year after closure of atrial septal defect.