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Prophylaxis and treatment of HIV-1 infection in pregnancy: Swedish recommendations 2007
Prophylaxis and treatment with antiretroviral drugs, a consequent low viral load, and the use of elective Caesarean section, are factors that radically decrease the risk of HIV transmission from mother to child during pregnancy and delivery. The availability of new antiretroviral drugs, updated general treatment guidelines and increasing knowledge of the importance of drug resistance, have necessi
In search of credibility: Pupils’ information practices in learning environments
Introduction. We aim to create an in-depth understanding of how pupils in upper secondary school negotiate the credibility and authority of information as part of their practices of learning. Particular focus is on the use of user-created resources, such as Wikipedia, where authorship is collective and/or hard to determine. Method. An ethnographic study was conducted in an upper secondary school c
Parallelization of a multiconfigurational perturbation theory
In this work, we present a parallel approach to complete and restricted active space second-order perturbation theory, (CASPT2/RASPT2). We also make an assessment of the performance characteristics of its particular implementation in the Molcas quantum chemistry programming package. Parallel scaling is limited by memory and I/O bandwidth instead of available cores. Significant time savings for cal
Software Quality Across Borders: Three Case Studies on Company Internal Alignment
Context Software quality issues are commonly reported when offshoring software development. Value-based software engineering addresses this by ensuring key stakeholders have a common understanding of quality. Objective This work seeks to understand the levels of alignment between key stakeholder groups within a company on the priority given to aspects of software quality developed as part of an
On the complexity of using performance measures: Enhancing sustained production improvement capability by combining OEE and productivity
The global speed of change within the manufacturing industry forces companies to constantly improve production performance. In that effort, performance measures are critical for driving and managing production improvements. Two of the most commonly used measures in operations are productivity and overall equipment efficiency (OEE). However, the potential of using these measures as improvement driv
Temperature adaptation of bacterial growth and C-14-glucose mineralisation in a laboratory study
Microbial decomposition of soil organic matter (SOM) is the source of most of the terrestrial carbon dioxide emission. Consequently, our ability to predict how climate warming will affect the global carbon (C) budget relies on our understanding of the temperature relationship and adaptability of microbial processes. We exposed soil microcosms to temperatures between 0 and 54 degrees C for 2 months
Contrast-enhanced MRI of human knee cartilage Clinical applications of the novel dGEMRIC technique to study glycosaminoglycan content in articular cartilage
Popular Abstract in Swedish Knäartros är en mycket vanlig sjukdom som leder till successiv nedbrytning och förlust av brosket i leden, en process som oftast tar 10-20 år. Detta orsakar svår smärta och stelhet och i dag saknas botande behandling mot artros. Det är dock rimligt att anta att en behandling har bättre förutsättningar att lyckas ju tidigare den sätts in. Man vet att det tidigt under sjuDelayed gadolinium-enhanced MRI of cartilage (dGEMRIC) is a new technique to study cartilage glycosaminoglycan (GAG) content. The negatively charged contrast agent Gd-DTPA2-, injected intravenously, distributes in the cartilage inversely to the likewise negatively charged GAG. The GAG concentration is reflected by the MRI parameter T1 and the Gd-DTPA2- concentration by the MRI parameter R1 (R1=1/T
Tonåringen i dagens samhällsvård : Problematik förknippad med institutionsvård på SiS-hem, familjehemsplacering och insatser inom öppenvården
The purpose of this paper was to establish what possible set of problems might be associated with three different types of social care available to young people. I chose to study institutionalised care, foster care and home-based intervention. Through interviews with three social workers, my aim was to answer the following questions: - What set of problems related to the teenagers tend to generate
Line Topology Identification Using Multiobjective Evolutionary Computation
The broadband capacity of the twisted-pair lines strongly varies within the copper access network. It is therefore important to assess the ability of a digital subscriber line (DSL) to support the DSL services prior to deployment. This task is handled by the line qualification procedures, where the identification of the line topology is an important part. This paper presents a new method, denoted
Discarding Heparins as Treatment for Progressive Stroke in Sweden 2001 to 2008
Background and Purpose-High-dose heparin has been used extensively to treat patients with progressive ischemic stroke, but the scientific support is poor and the current stroke guidelines advise against its use. We studied how heparin treatment for progressive stroke has been discarded in Sweden. Methods-All 78 hospitals in Sweden that admit acute stroke patients participate in Riks-Stroke, the Sw
Opposite Patterns of Diurnal Activity in the Box Jellyfish Tripedalia cystophora and Copula sivickisi
Cubozoan medusae have a stereotypic set of 24 eyes, some of which are structurally similar to vertebrate and cephalopod eyes. Across the approximately 25 described species, this set of eyes varies surprisingly little, suggesting that they are involved in an equally stereotypic set of visual tasks. During the day Tripedalia cystophora is found at the edge of mangrove lagoons where it accumulates cl
Functional properties of galectin-3. Beyond the sugar binding.
Popular Abstract in Uncoded languages Kronična upala je u podlozi mnogih bolesti modernog čovjeka kao što su djiabetes, astma, ateroskleroza itd. Upalu predvode različiti tkivni makrofagi. Proteini iz porodice galektina, proizvedeni u makrofagima, dodatno pridonose razvoju bolesti, stoga je od velikog interesa odgonetnuti različite funkcije galektina. Ovaj rad nastoji identificirati specifične uloContemporary diseases like diabetes, asthma, atherosclerosis etc. are marked by chronic inflammation, often supported by the activity of different macrophages. Proteins from galectin family were found to contribute to disease pathophysiology. Therefore, there is an intensive interest in understanding different galectin functions. The aim of this thesis was to pin-point specific galectin-3 roles in
The effects of 55 years of different inorganic fertiliser regimes on soil properties and microbial community composition
Agricultural fertilisation increases crop yields but can cause environmental damage, thus reductions in inorganic fertiliser application have been advocated. Farmer usage of phosphate rock has declined over the last decade, which may lead to soil nutrient depletion that undermines future crop production. We investigated the long-term (55 years) effects of eight different inorganic fertiliser regim
Infants with colic - Parents’ experiences in short and long perspectives and the effect of acupuncture treatment on crying, feeding, stooling and sleep
Popular Abstract in Swedish Spädbarn med kolik – föräldrars upplevelse i ett kortare och ett längre perspektiv samt effekten av akupunktur på barnets skrik, ätande, avföringsmönster och sömn. Spädbarnskolik definieras som ett tillstånd där ett för övrigt friskt barn skriker och gnäller mer än tre timmar per dag mer än tre dagar i veckan. Kolik drabbar ca 10 % av nyfödda barn i västvärlden. Både bInfantile colic, involving an otherwise healthy infant crying and fussing more than three hours per day and more than three days per week, is a common problem in Western countries. Both the infant and the parents suffer during the months of persistent crying and there is a risk that the establishing of the early relationship might be disturbed. Safe and effective treatment that provides relief in
Cooperation between gatekeepers in sickness insurance - the perspective of social insurance officers. A qualitative study.
ABSTRACT: BACKGROUND: Objective was to describe variations in how social insurance officers conceive the cooperation with the health care in their daily work with sick leave. METHODS: Fifteen social insurance officers (SIOs) working with administration of sickness benefits were interviewed. They were purposefully recruited to represent different parts of the social insurance office organization, d
Nourishment design and evaluation: applicability of model concepts
Investigation of the enzyme Bacillus agaradhaerens Cel 5a as an analytical tool in mass spectral characterisation of methylcelluloses
Two methylcelluloses (MC) were investigated by partial hydrolysis followed by direct infusion electrospray ionisation mass spectrometry (ESI-MS). Partial hydrolysis was achieved either enzymatically or by acid hydrolysis. Enzyme hydrolysis was performed using the endoglucanase Bacillus agaradhaerens Cel 5a. Three different hydrolysis buffer solutions were investigated in order to deter-mine which
CD99 is a novel prognostic stromal marker in non-small cell lung cancer
The complex interaction between cancer cells and the microenvironment plays an essential role in all stages of tumourigenesis. Despite the significance of this interplay, alterations in protein composition underlying tumourstroma interactions are largely unknown. The aim of this study was to identify stromal proteins with clinical relevance in non-small cell lung cancer (NSCLC). A list encompassin
Genetic analysis implicates APOE, SNCA and suggests lysosomal dysfunction in the etiology of Dementia with Lewy Bodies.
Clinical and neuropathological similarities between Dementia with Lewy Bodies (DLB), ParkinsonÕs and AlzheimerÕs diseases (PD and AD, respectively) suggest that these disorders may share etiology. To test this hypothesis we have performed an association study of 54 genomic regions, previously implicated in PD or AD, in a large cohort of DLB cases and controls. The cohort comprised 788 DLB cases an
