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Three sets of research criteria are available for diagnosis of Alzheimer's disease in subjects with mild cognitive impairment: the International Working Group-1, International Working Group-2, and National Institute of Aging-Alzheimer Association criteria. We compared the prevalence and prognosis of Alzheimer's disease at the mild cognitive impairment stage according to these criteria. Subjects wi
Symbioses between plant roots and mycorrhizal fungi are thought to enhance plant uptake of nutrients through a favourable exchange for photosynthates. Ectomycorrhizal fungi are considered to play this vital role for trees in nitrogen (N)-limited boreal forests. We followed symbiotic carbon (C)N exchange in a large-scale boreal pine forest experiment by tracing 13CO2 absorbed through tree photosynt
Background: The aim was to evaluate data quality and psychometric properties of an instrument for measurement of health-related quality of life: DISABKIDS Chronic Generic Module (DCGM-37) used in school-aged children with cancer. Methods: All school-children diagnosed with cancer in Sweden during a two-and-a-half year period were invited to participate in the study. Analysis was performed on combi
Abstract in UndeterminedIn this article we study the evolution of marriage seasonality in relation to economic change, particularly connected to changes in labour supply and work intensity of the kind implied by the ‘industrious revolution’. The focus is on southern Sweden in 1685–1894, which was a period of agricultural transformation and early industrialization, when we would expect to see an in
ABSTRACT: BACKGROUND: The conditions for steam pretreatment of sugar cane bagasse and leaves were studied using CO2 as an impregnating agent. The following conditions were investigated: time (5 to 15 min) and temperature (190 to 220 degrees C). The pretreatment was assessed in terms of glucose and xylose yields after enzymatic hydrolysis and inhibitor formation (furfural and hydroxymethylfurfural)
This thesis presents the results of an investigation into BIM implementation prerequisites emerging as a set of procedural supporting mechanisms that may enable design, construction and operating (DCO) organisations to advance their deployment of Building Information Modelling (BIM) technology, and improve construction project outcomes. Today, BIM is centre-stage within the construction sector the
Surface modification of polyurethane (PUR) surfaces was carried out by using three different amphiphilic polymers. Two of the polymers were graft copolymers, having backbones consisting of poly(methyl methacrylate-co-ethylhexyl acrylate) and poly(styrene-co-acrylamide), respectively, and poly(ethylene oxide) PEO 2000 grafts. The third polymer was a commercially available poly(ethylene oxide-b-prop
The aim of the study was to examine how substance abuse influences social relationships to families, friends and others. Five ex addicts in a treatment centre were interviewed. We used thematic interviews with themes that we regarded as relevant for our study. In the analysis we applied the theoretical concept of symbolic interactionism. Theories of emotions also helped us to explain feelings that
Background: Perceived occupational value is an important treatment outcome but is still relatively unexplored as a phenomenon. Aim: To evaluate whether the Balancing Everyday Life (BEL) intervention for people with mental health issues was effective compared to Standard Occupational Therapy (SOT) regarding improvement on three dimensions of occupational value (concrete, socio-symbolic and self-rew
Given population ageing and the emphasis on in-home care, more working-age adults are facing the demands of providing unpaid care to the elderly with potential implications for their own well-being. Such effects likely vary across Europe because care is differently organized with a differing emphasis on public support, dependence on family, and orientation toward gender equality. We studied the re
We undertake a fundamental study of network equilibria modeled as solutions of fixed-point equations for monotone linear functions with saturation nonlinearities. The considered model extends one originally proposed to study systemic risk in networks of financial institutions interconnected by mutual obligations. It is one of the simplest continuous models accounting for shock propagation phenomen
Aim: To study whether a specific cognitive profile can be identified for children born extremely preterm (EPT) by investigating: 1) strengths and weaknesses not revealed by Full-Scale IQ, 2) overlap between different cognitive deficits and 3) proportion of EPT children with multiple deficits. Methods: We analysed data from the 4th version of Wechsler Intelligence Scales for Children in EPT childre
Genetic variations have a multitude of effects on proteins. A substantial number of variations affect protein–solvent interactions, either aggregation or solubility. Aggregation is often related to structural alterations, whereas solubilizable proteins in the solid phase can be made again soluble by dilution. Solubility is a central protein property and when reduced can lead to diseases. We develo
IntroductionChildren affected by Paediatric Feeding Disorder (PFD) cannot consume enough nourishment by mouth. PFD is highly prevalent and can affect the child's growth and development as well as family life.AimTo illuminate Swedish parents’ experiences of living with a child with PFD.MethodSemi-structured interviews via telephone or video calls were conducted with 14 purposefully recruited mother
Islet dysfunction is central in type 2 diabetes and full-blown type 2 diabetes develops first when the beta cells lose their ability to secrete adequate amounts of insulin in response to raised plasma glucose. Several mechanisms behind beta cell dysfunction have been put forward but many important questions still remain. Furthermore, our understanding of the contribution of each islet cell type in
BACKGROUND: Although highly active antiretroviral therapy (HAART) reduces mortality in the developed world, it remains undocumented in resource-poor settings. We assessed the effect of HAART on patient mortality and tuberculosis incidence rate under routine clinical care conditions in Ethiopia. The objective of this study was to assess the effect of HAART on patient mortality and tuberculosis inci
Incorporating time as a unit of analysis can enrich the study of agency by showing the specific ways in which actors are temporally constrained when responding to economic disturbances. In this paper, this is done by examining how the behavior of actors is affected by timing norms such as term limits that may be associated with an actor's position, as for example, an elected mayor or university vi
Incidence of differentiated thyroid carcinoma (DTC) varies considerably between ethnic groups, with particularly high incidence rates in Pacific Islanders. Here, we conducted a genome-wide association study (GWAS) involving 1,554 cases/1,973 controls of European ancestry and 301 cases/348 controls of Oceanian ancestry from the EPITHYR consortium. Our results confirmed the association with the know
Neurodegenerative disorders such as Alzheimer's disease (AD) represent a mounting public health challenge. As these diseases are difficult to diagnose clinically, biomarkers of underlying pathophysiology are playing an ever-increasing role in research, clinical trials, and in the clinical work-up of patients. Though cerebrospinal fluid (CSF) and positron emission tomography (PET)-based measures ar
