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This study describes the evaluation and characterization of a self-nanoemulsifying drug delivery system (SNEDDS) consisting of a nonionic surfactant (Cremophor RH40), a mixture of long chain mono-, di-, and triacylglycerides (Maisine 35-1 and Sesame oil) and ethanol. Compositions containing 10% (w/w) ethanol, 40%-60% (w/w) lipid content, and 30%-50% (w/w) Cremophor RH40 were identified as pharmace
Background and aims Natural and semi-natural, non-fertilized calcareous soils are consistently low in soluble and easily exchangeable phosphate. An over-utilization, or possibly an immobilization, of inorganic P in the tissues of calcifuge plants may take place, if such plants are forced to grow on a calcareous soil, though this has not been experimentally demonstrated. The objectives of this stud
Food selectivity and grazing impact by Acartia bifilosa, Temora longicornis and Centropages typicus on Dinophysis spp. plankton assemblages were experimentally investigated in the Baltic Sea. Toxin analyses were carried out on phyto- and zooplankton-dominated size fractions from field-collected samples to assess if toxins produced by Dinophysis spp. would end up in the zooplankton. All copepod spe
BACKGROUND: Ventilator resetting is frequently needed to adjust tidal volume, pressure and gas exchange. The system comprising lungs and ventilator is so complex that a trial and error strategy is often applied. Comprehensive characterization of lung physiology is feasible by monitoring. The hypothesis that the effect of ventilator resetting could be predicted by computer simulation based on a phy
Popular Abstract in Swedish I ben finns tre olika sorters celler, osteoblaster, osteocyter och osteoklaster. Osteoblaster och osteocyter härstammar från stamceller som kallas stödjevävnadens stamceller och svarar för uppbyggnad och upprätthållande av benvävnaden medan osteoklasterna härstammar från de blodbildande stamcellerna och står för nedbrytning av ben. Ben är den enda vävnaden i kroppen somBone morphogenic proteins, BMPs, are a group endogenous proteins that are highly conserved through evolution. The amino acid sequences of about 15 different BMPs are now known and recombinant human BMPs are commercially available. Implantation of an individual BMP protein is sufficient to induce bone formation even at a subcutaneous site. Our initial studies discovered inhibition of bone formation
Luke’s account of the last supper (22:14–38) is here analyzed according to the pattern of chreia elaboration, which was one of the preparatory rhetorical exercises known as Progymnasmata in the Hellenistic school. The study begins with a brief overview of the preserved progymnastic textbooks or manuals and their contents, and then proceeds to show how influences from the exercises can be detected
Popular Abstract in Swedish Vad pysslar kräftorna med? Kräftor äter allt! Jag har visat att kräftor äter gamla blad från träd, alger, vattenväxter och även smådjur som till exempel sländlarver, iglar och sövattensgråsuggor. Dessa olika typer av mat har olika näringsvärde. Om vi jämför med vad vi äter så är det ju uppenbart att t.ex. västerbottenpaj och kokta kräftor har olika näringsvärde. Pajen I show that crayfish consume detritus, algae, macrophytes, and an array of invertebrates. Crayfish were found to reduce invertebrate densities. However, prey mobility seemed to be a key factor regulating the strength of interactions between crayfish and prey. Since crayfish seek to maximize growth, they benefit from feeding on invertebrates, shown to promote high growth rates. I found crayfish to
The Nordic Grid facility (NorduGrid [1]) came into operation during summer 2002 when the Scandinavian ATLAS HEP group started to use the Grid for the ATLAS Data Challenges (DC) and was thus the first Grid ever contributing to an ATLAS production. Since then, the Grid facility has been in continuous 24/7 operation. NorduGrid is being used by a growing set of active users from various scientific are
Objective: The use of cytological specimens to evaluate tumour biomarkers in metastatic breast cancer lesions has attracted increased interest because of the considerable number of reports that have shown discordance between the primary tumour and metastatic lesion. Oestrogen receptor (ER) and progesterone receptor (PgR) assays are crucial for the management of patients with breast cancer, in bot
The purpose of this paper is to briefly discuss the rationale for using Student Response Systems (SRS) and to share our experience of using this teaching technology in a training session. Our experiences support existing pedagogical research and show that SRS can be used to transform traditionally passive lecture-based classes into stimulating, active learning environments. Students demonstrate be
Spirocyclic acetal structures have recently received growing attention in polymer science due to their dual potential to raise the glass transition temperature (Tg) and enable chemical recycling of biobased polymers. In the present work, a vanillin-based diol with a spirocyclic acetal structure was incorporated in a series of rigid amorphous polyesters based on neopentyl glycol and dimethyl t
Theories of taste-based discrimination predict that competitive pressures will drive discriminatory behavior out of the market. The authors analyze how firm takeovers and product market competition affect firms' gender composition and gender wage gap using detailed matched employer-employee data. Taking into account several endogeneity concerns while using a difference-in-difference framework, the
Popular Abstract in Swedish Många olika proteiner kan produceras med hjälp av rekombinanta DNA tekniker. Ofta sätts vektorn som kodar för det rekombinanta proteinet in i bakterien E. coli, då den är välkänd. Det är viktigt att producera mycket celler för att uppnå hög produktivitet. Detta görs genom att näringsämnet (ofta glukos) tillsätts kontinuerligt till en så kallad semisats reaktor. TillsatsThe recombinant DNA techniques have made it possible to produce many different proteins for a wide range of applications. The vector encoding for the recombinant protein is often inserted in the bacterium E. coli as it is a well studied and a well-known organism. To achieve a high productivity, it is important to reach a high cell density. This is obtained through fed-batch operation where the nut
ere should be fitness costs associated with the defense, otherwise it should be permanent. Thus, in the absence of predators and with limited resources, defended individuals are expected to be outcompeted by individuals lacking the costly defense. Crucian carp, Carassius carassius, increase in body depth in response to chemical stimuli from piscivorous fish, and the deeper body constitutes a morph
Mycosis fungoides (MF) is a primary cutaneous T-cell lymphoma with slow disease progression. There is a lack of descriptive data from Sweden concerning patients with this diagnosis. This study extracted data on patients admitted to the dermatology department at Lund University Hospital, Sweden from 1996 to 2010. Forty-four patients with clinically and histopathologically verified MF were identifie
The part-load behaviour of combined cycle power plants (CCPP) equipped with post-combustion CO2 capture is analyzed. Different CCPP configurations are compared, including single-, dual- or triple-pressure level steam generators. The gas turbine is a single shaft unit using the variable guide vanes and fuel flow to control the load. The 90% CO2 capture is achieved using monoethanolamine (MEA 30%wt)
Aim The impact of multiple stressors on biodiversity is one of the most pressing questions in ecology and biodiversity conservation. Here we critically assess how often and efficiently two main drivers of global change have been simultaneously integrated into research, with the aim of providing practical solutions for better integration in the future. We focus on the integration of climate change
Background: Residual air accumulated air in the pulmonary veins constitutes a challenge to achievment of complete de-airing in open left heart surgery. To adress this problem, a conceptual method for de-airing was developed in Lund comprising bilateral opening of the pleurae to induce pulmonary collapse and a strategy with gradual pulmonary reperfusion and ventilation at weaning from cardiopulmona
Background/Objectives A cascade of gene activations under the control of Notch signalling is required during T-cell specification, when T-cell precursors gradually lose the potential to undertake other fates and become fully committed to the T-cell lineage.We elucidate how the gene/protein dynamics for a core transcriptional module governs this important process by computational means. Methods We
