Filetype
We discuss the preimaginal development of the mosquito Aedes aegypti from the point of view of the statistics of developmental times and the final body-size of the pupae and adults. We begin the discussion studying existing models in relation to published data for the mosquito. The data suggest a developmental process that is described by exponentially distributed random times. The existing data s
A whole complement ELISA-based assay kit, primarily designed to screen for deficiencies in components of the complement system was developed during a European Union grant involving more than a dozen European scientists and a small-medium enterprise company (Wieslab, which later merged into Eurodiagnostica). The consortium was led by Prof. Mohamed R. Daha who had already guided a preceding European
Circadian clocks optimize the timing of physiological processes in synchrony with daily recurring and therefore predictable changes in the environment. Until the late 1990s, circadian clocks were thought to exist only in the central nervous systems of animals; elegant studies in cultured fibroblasts and using genetically encoded reporters in Drosophila melanogaster and in mice showed that clocks a
Due to significant improvement in the pre-hospital treatment of patients with out-of-hospital cardiac arrest (OHCA), an increasing number of initially resuscitated patients are being admitted to hospitals. Because of the limited data available and lack of clear guideline recommendations, experts from the EAPCI and "Stent for Life" (SFL) groups reviewed existing literature and provided practical gu
The fibrillation process of the islet amyloid polypeptide (IAPP) and its fragment (IAPP((20-29))) was studied by means of Thioflavin T (ThT) fluorescence and transmission electron microscopy in the absence and presence of N-isopropylacrylamide:N-tert-butylacrylamide (NiPAM:BAM) copolymeric nanoparticles. The process was found to be strongly affected by the presence of the nanoparticles, which reta
Astrocytes are essential cells for normal brain functionality and have recently emerged as key players in many neurological diseases. However, the limited availability of human primary astrocytes for cell culture studies hinders our understanding of their physiology and precise role in disease development and progression. Here, we describe a detailed step-by-step protocol to rapidly and efficientl
One of the benefits of cooperative hunting may be that predators can subdue larger prey. In spiders, cooperative, social species can capture prey many times larger than an individual predator. However, we propose that cooperative prey capture does not have to be associated with larger caught prey per se, but with an increase in the ratio of prey to predator body size. This can be achieved either b
Background: The COVID-19 pandemic presents great challenges on transmission prevention, and rapid diagnosis is essential to reduce the disease spread. Various diagnostic methods are available to identify an ongoing infection by nasopharyngeal (NPH) swab sampling. However, the procedure requires handling by health care professionals, and therefore limits the application in household and community s
Compared to the well-known drivers of spatial variability in gross primary productivity (GPP), the relative importance of climatic variables, soil properties and plant traits to the spatial variability in net ecosystem exchange of CO2 between terrestrial ecosystem and atmosphere (NEE) is poorly understood. We used principal component regression to analyze data from 147 eddy flux sites to disentang
Recent advances in proteomic technologies have made high throughput profiling of low abundance proteins in large epidemiological cohorts increasingly feasible. We investigated whether aptamer-based proteomic profiling could identify biomarkers associated with future development of type 2 diabetes (T2DM) beyond known risk factors. We identified dozens of markers with highly significant associations
The cardiac hormone atrial natriuretic peptide (ANP) is a central regulator of blood volume and a therapeutic target in hypertension and heart failure. Enhanced ANP activity in such conditions through inhibition of the degradative enzyme neprilysin has shown clinical efficacy but is complicated by consequences of simultaneous accumulation of a heterogeneous array of other hormones. Targets for spe
Recently we have identified a dopamine-producing system in the gastric mucosa of rats. All the available morphological data suggest that parietal cells synthesize dopamine. In the present study we investigated the dopaminergic characteristics of isolated parietal cells by different methods. Mixed gastric mucosal cells were isolated and size-fractionated by elutriation. The proportion of neurons, p
Facing increasing pressure to decarbonize, innovation within the shipping sector has turned to low-and zero carbon solutions. In this paper we investigate how the development and implementation of biodiesel and liquefied biogas (LBG) in Norwegian coastal shipping has been influenced by the technological alignment with fossil fuels. We understand this influence to emanate from the (mis)match of bioFacing increasing pressure to decarbonize, innovation within the shipping sector has turned to low-and zero carbon solutions. In this paper we investigate how the development and implementation of biodiesel and liquefied biogas (LBG) in Norwegian coastal shipping has been influenced by the technological alignment with fossil fuels. We understand this influence to emanate from the (mis)match of bio
BACKGROUND: The COVID-19 pandemic has had a profound effect on the emotional well-being of expecting mothers. Sweden's unique strategy for managing COVID-19 involved no national lockdown. Emphasis was instead placed on limiting crowding and asking citizens to practice social distancing measures.AIM: To gain a deeper understanding of how women not infected by SARS-CoV-2 experienced pregnancy during
A dyadic algorithm for diagonalizing an arbitrary positive definite band matrix, referred to as a band Gramian, is obtained to efficiently orthogonalize the B-splines. The algorithm can be also used as a fast inversion method for a band Gramian characterized by remarkable sparsity of the diagonalizing matrix. There are two versions of the algorithm: the first one is more efficient and is applicabl
År 2019 besökte 1,9 miljoner personer i åldrarna 19 år eller äldre akutmottagningarna i Sverige. Vistelsetiderna på akutmottagningarna ses samtidigt i stora delar av landet öka. Patientflöde och arbetsbelastning är ständigt i förändring och de senaste åren har vårdplatsläget orsakat stora bekymmer med kvarstannande patienter, så kallad crowding. Tidigare forskning visar att sjuksköterskor ofta bliDuring 2019 the emergency departments in Sweden had 1.9 million visitors aged 19 years or older seeking medical assistance. Throughout the majority of Sweden the time spent at the emergency departments is increasing according to the National Board of Health and Welfare (Socialstyrelsen, 2020). Several factors influence the work performed by registered nurses at an emergency department. The flow o
Investeringsrådgivning är när en personlig rekommendation avseende ett finansiellt instrument lämnas till en kunde. Det finns inga begränsningar i hur det ska gå till, utan det kan både genom ett fysiskt möte och via ett automatiskt verktyg. Vid investeringsrådgivning finns det omfattande krav som måste uppfyllas. Kraven handlar huvudsakligen om information som ska lämnas till kund, en bedömning aProviding investment advice is the act of giving a personalized investment advice to a client in relation to a financial instrument. There is no set form for how investment advice is provided, it can be done by a person in a meeting, as well as by an automated tool. The legislation that must be complied with while providing investment advice is extensive. The legislation mainly stipulates three re
