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Older patients' perception of their own capacity to regain pre-fracture function after hip fracture surgery – an explorative qualitative study

Aims and objectives To explore healthy older patients' perceptions of their own capacity to regain pre-fracture function in the acute phase following hip fracture surgery. Background The incidence of hip fractures is expected to increase. In Sweden, of the patients who sustain a hip fracture, 40 per cent are healthy and lived independently pre fracture. However, a hip fracture often results in dec

Cadmium inhibits proteoglycan and procollagen production by cultured human lung fibroblasts

Chronic inhalation of cadmium at the workplace or in cigarette smoke is associated with emphysema, a disease characterized by extensive disruption of lung connective tissue. We have previously shown that cadmium, at noncytotoxic doses, inhibits fibroblast procollagen production in vitro, with maximal inhibitory effects of 69 +/- 6% (P < 0.01) at 30 &microM cadmium chloride (CdCl2). In this pap

Integration of Wind Power in Medium Voltage Networks - Voltage Control and Losses

Since some years ago greenhouse gases and especially carbon dioxide have become one of the most widely debated issues. To reduce the emission of carbon dioxide and nuclear waste, renewable energy sources as for example wind power plants have become very successful. These generation units are normally small compared to common thermal power plants and they are often placed distributed and connected

Factors associated with health-related quality of life and burden on relatives of older people with multi-morbidity : a dyadic data study

BACKGROUND: This study aimed to identify factors associated with health-related quality of life (HRQoL) and the burden on the relatives of older people with multi-morbidity.METHODS: A secondary analysis of baseline data from 296 dyads, including older patients with multimorbidity and their relatives, which were previously collected in a randomized study. The analysis was conducted to select correl

The Orthostatic Hypotension Questionnaire in Swedish tested in patients with parkinsonism

Background: Orthostatic hypotension (OH) is common among older people and in particular in conditions like Parkinson’s disease (PD). The OH Questionnaire (OHQ) has been proposed as a useful patient-reported assessment tool consisting of the OH Symptom Assessment (OHSA), OH Daily Activity Scale (OHDAS), and a composite score. Aims of the Study: To translate the OHQ into Swedish and assess its psych

Epstein–Barr virus infection after adolescence and human herpesvirus 6A as risk factors for multiple sclerosis

Background and purpose: Infections with human herpesvirus 6A (HHV-6A) and Epstein–Barr virus (EBV) have been linked to multiple sclerosis (MS) development. For EBV, late infection has been proposed as a risk factor, but serological support is lacking. The objective of this study was to investigate how age affects the EBV and HHV-6A associated risks of developing MS. Methods: In this nested case–co

RIFM fragrance ingredient safety assessment, 2-cyclohexylcyclohexanone, CAS Registry Number 90-42-6

Summary: The existing information supports the use of this material as described in this safety assessment. 2-Cyclohexylcyclohexanone was evaluated for genotoxicity, repeated dose toxicity, reproductive toxicity, local respiratory toxicity, phototoxicity/photoallergenicity, skin sensitization, and environmental safety. Data and read-across to 2-tert-butylcyclohexanone (CAS # 1728-46-7) show that 2

Climacteric medicine: European Menopause and Andropause Society (EMAS) 2004/2005 position statements on peri- and postmenopausal hormone replacement therapy

In women experiencing distressing climacteric symptoms during the peri- and postmenopause there is conclusive evidence from abundant randomised controlled trials that systemic hormone replacement therapy (HRT) of any type affords symptom relief, with no alternative treatment producing similar effect. Though this evidence is accumulating, the question of how to provide best clinical practice in an

What is ideal genetic counselling? A survey of current international guidelines

The objective of this article is to review guidelines that address counselling in the context of genetic testing in order to summarise what aspects of counselling they consider most important, and to examine how they construct the ideal of genetic counselling. Guidelines were collected by examining the websites of different international professional, political, ethical and patient organisations,

Generation of synthesis gas for fuels and chemicals production

Popular Abstract in Swedish Dagens samhälle är mycket beroende av fordonsbränslen och kemikalier som producerats av råolja. Framtidens tillgång på råolja är oviss, det enda som är säkert är att det är en ändlig resurs. Användningen av olja bidrar dessutom till koldioxidutsläpp till atmosfären. För att säkra framtida tillförsel av energi och kemikalier till samhället och för att uppnå ett mer klimaMany scientists believe that the oil production will peak in the near future, if the peak has not already occurred. Peak oil theories and uncertain future oil deliveries have stimulated interest in alternative sources of fuel and chemicals. This interest has been enhanced by concerns about energy security and about the climate change caused by emissions of carbon dioxide. The result has been incre

Signs of Scholarship of Teaching and Learning at a Faculty of Medicine

Many medical schools and faculties are actively promoting scholarly inquiry into teaching and learning to improve education. The Faculty of Medicine at Lund University, Sweden, has developed a Teaching Academy with criteria for membership founded in Scholarship of Teaching and Learning (SoTL). Furthermore, the Faculty arranges a conference in medical education and also organises courses to support

The influence of RBE variations in a clinical proton treatment plan for a hypopharynx cancer

Currently, most clinical range-modulated proton beams are assumed to have a fixed overall relative biological effectiveness (RBE) of 1.1. However, it is well known that the RBE increases with depth in the spread-out Bragg peak (SOBP) and becomes about 10% higher than mid-SOBP RBE at 2 mm from the distal edge (Paganetti 2003 Technol. Cancer Res. Treat. 2 413-26) and can reach values of 1.3-1.4 in v

Evaluation of the plant phenology index (PPI), NDVI and EVI for start-of-season trend analysis of the Northern Hemisphere boreal zone

Satellite remote sensing of plant phenology provides an important indicator of climate change. However, start of the growing season (SOS) estimates in Northern Hemisphere boreal forest areas are known to be challenged by the presence of seasonal snow cover and limited seasonality in the greenness signal for evergreen needleleaf forests, which can both bias and impede trend estimates of SOS. The ne

Preoperative alcohol cessation prior to elective surgery

Background Hazardous drinking has been associated with an increased postoperative complication rate after surgery. Common complications include postoperative infections, cardiopulmonary complications, and bleeding episodes. Preoperative abstinence may to some degree reverse alcohol-induced pathophysiological processes and thus prevent postoperative complications. Objectives To assess the effect of

ICRP perspective on criteria of acceptability for medical radiological equipment

The International Commission on Radiological Protection (ICRP) does not have a specific publication or recent detailed advice on acceptability criteria and suspension levels for medical radiological equipment. However, a number of the Commission's publications clearly stress the need to carry out acceptance testing of radiological equipment. Such general recommendations are frequent in earlier and

Platelet activation and anti-phospholipid antibodies collaborate in the activation of the complement system on platelets in systemic lupus erythematosus.

Anti-phospholipid (aPL) antibodies are important contributors to development of thrombosis in patients with the autoimmune rheumatic disease systemic lupus erythematosus (SLE). The underlying mechanism of aPL antibody-mediated thrombosis is not fully understood but existing data suggest that platelets and the complement system are key components. Complement activation on platelets is seen in SLE p

A CNN-Specific Integrated Processor

Integrated Processors (IP) are meant to supply algorithm-specific cores to a micro-electronic system. They are usually developed separately, and upon success turned into a part, that either by programming or by configuration can be re-used within many systems. This paper looks at architectures for Cellular Neural Networks (CNN) to become realized as IP. First current digital implementations are re

HIF-mediated metabolic switching in bladder outlet obstruction mitigates the relaxing effect of mitochondrial inhibition.

Prior work demonstrated increased levels of hypoxia-inducible factor-1α (HIF-1α) in the bladder following outlet obstruction, associated with bladder growth and fibrosis. Here we hypothesized that HIF induction in outlet obstruction also switches energetic support of contraction from mitochondrial respiration to glycolysis. To address this hypothesis, we created infravesical outlet obstruction in

Integrering av fastighetsförvaltning i ombyggnadsprojekt

Studien syftar till att undersöka hur fastighetsbolag integrerar förvaltningsaspekter i ombyggnader av deras fastigheter. Fokus kommer ligga på hur förvaltningsaspekter och underhållsåtgärder har inkluderats samt hur samarbetet mellan förvaltningen och projektledningen sker. Studien ska även identifiera förbättringsmöjligheter och diskutera alternativa metoder. Målsättningen för studien är att besThe study aims to investigate how real estate companies integrate facility management aspects into the reconstruction of their properties. The focus will be on how facility management aspects and maintenance measures are included, as well as how the collaboration between facility managers and project managers takes place. The study will also identify areas for improvement and discuss alternative m

Voice fatigue subtyping through individual modeling of vocal demand reponses

Recognizing individual variability is essential for developing targeted, personalized medical interventions. Vocal fatigue is a prevalent symptom and complaint among occupational voice users, but its identification has yielded mixed results. Vocal fatigue is a complex issue with heterogeneous biophysiological responses to vocal demands among individuals. This research aims to classify individuals