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The Role of the Cortico-Basal Ganglia-System in Voluntary Movements

Popular Abstract in Swedish Nervsystemet är sannolikt en av de mest vidunderliga strukturer som skapats i detta universum - denna avhandling hade till exempel varken kunnat skrivas eller läsas utan det. Som av en slump handlar den också om just nervsystemet och läsande och skrivande är två exempel på olika funktioner som möjliggjorts på grund av det. Även om dessa utgör funktioner som är ovanliga Bodies with multiple limbs and joints have endless possibilities to move around in their surrounding space. How the nervous system controls this amount of degrees of freedom in motor execution is a question under vigorous debate. In an ambition to explore related aspects of motor control we conducted parallel electrophysiological recordings of motor circuits in the cortex and basal ganglia in the

Services of General Economic Interest and the Swedish Railway Monopoly

Even though the Community is based upon the principle of an open market economy with free competition, there are certain exemptions to this notion. One of the exemptions is the fulfilment of services of general economic interest, an exemption that elucidates the delicate conflict of interest between Member States' prerogative to provide accessible and affordable public services, and the Commun

OARSI recommendations for the management of hip and knee osteoarthritis, part I: critical appraisal of existing treatment guidelines and systematic review of current research evidence

PURPOSE: As a prelude to developing updated, evidence-based, international consensus recommendations for the management of hip and knee osteoarthritis (OA), the Osteoarthritis Research Society International (OARSI) Treatment Guidelines Committee undertook a critical appraisal of published guidelines and a systematic review (SR) of more recent evidence for relevant therapies. METHODS: Sixteen exper

Negative-pressure wound therapy for deep sternal wound infections reduces the rate of surgical interventions for early re-infections

OBJECTIVES: To evaluate the outcome of treatment for deep sternal wound infection (DSWI) in a nationwide patient cohort, before and after the introduction of negative-pressure wound therapy (NPWT). METHODS: This was a population-based cohort of all patients treated for DSWI in Iceland out of 2446 open heart operations performed between 2000 and 2010. Length of hospital stay, survival and reoperati

Trait matching of flower visitors and crops predicts fruit set better than trait diversity

Understanding the relationships between trait diversity, species diversity and ecosystem functioning is essential for sustainable management. For functions comprising two trophic levels, trait matching between interacting partners should also drive functioning. However, the predictive ability of trait diversity and matching is unclear for most functions, particularly for crop pollination, where in

Let us laugh at gender inequality till it is not a problem anymore : a qualitative case study of the Facebook page Man Who Has It All's satirical social imaginary

Since the feminist movement developed today, women still face the challenges of gender inequality. In some countries, women even cannot see the hope for change. Hence, when aiming to counteract gender inequality, it is important to address the macro level and the micro level. The research focuses on the micro level of resistance to gender inequality instead of large-scale protest movements to exp

Mellan skuld och vård - Är tillräknelighetsrekvisitet en lösning på straffrättens dilemman? En uppsats om psykiskt störda lagöverträdares ansvarsförutsättningar i svensk respektive dansk rättsordning.

I denna uppsats har psykiskt störda lagöverträdares ansvarsförutsättningar i svensk- respektive dansk rättsordning undersökts. Sveriges val, att i samband med brottsbalkens införande 1965, avskaffa tillräknelighetsbestämmelserna, har genom åren mött en hel del kritik. Uppsatsen avser att besvara frågan kring huruvida ett tillräknelighetsrekvisit bör återinföras i svensk lagstiftning eller ej. DåThis thesis examines the conditions of liability for mentally disturbed offenders in the legal systems of Sweden and Denmark. Sweden’s decision to abolish the insanity defense provisions upon the introduction of the Penal Code in 1965 has faced considerable criticism over the years. This study aims to address whether a legal requirement for criminal accountability should be reintroduced into Swedi

School performance and substance use disorders in early adulthood among non-immigrant and immigrant populations in Sweden

Individuals with immigrant background generally perform less well in school than non-immigrants. Performing well in school may decrease the risk of substance use disorder (SUD). We investigated whether higher school performance is associated with a decreased risk of SUD in early adulthood among immigrants and non-immigrants and whether subsequent educational attainment and employment status partly

European Sexual Dis/Integration : An Agonistic Paradox of Legitimacy in a Contested Union

Denna avhandling undersöker hur legitimiteten i Europeiska Unionens (EU) stöd för LGBTIQ-jämlikhet bör bedömas och hävdas mot bakgrund av ytterhögerns främjande av en konkurrerande vision för europeiskt samarbete som är rotad i anti-genderpolitik. Med utgångspunkt i agonistisk och queer-teori konceptualiseras EU:s stöd för LGBTIQ-jämlikhet som ett försök att skapa en europeisk pro-LGBTIQ-konsensusThis dissertation examines how the legitimacy of the European Union’s (EU) support for LGBTIQ equality should be assessed and asserted amid the far right’s promotion of a rival vision for European cooperation rooted in anti-gender politics. Drawing on agonistic and queer theory, the EU’s support for LGBTIQ equality is conceptualised as an effort to forge a European pro-LGBTIQ consensus, termed sex

SCHOOLS at ‘FRONT ROW’ public buildings in relation to societal presence and social exclusion

In analyses of affordances and opportunities in different neighbourhoods it is found that access to public buildings and a well-functioning public space are of outmost importance. This is found to be especially important in neighbourhoods having a population with fewer resources, areas often discussed in terms as ‘deprived’ or ‘excluded’, concepts that alludes to the phenomenon of segregation. Pre

When irony is faster than its literal control : The role of mindreading during irony comprehension

Irony is a heavily context-dependent pragmatic phenomenon. But what is it about context that facilitates or blocks irony comprehension? Based on the echoic account, we suggest that a context facilitates irony comprehension when it makes manifest a speaker's intentions and attitude, i.e., when a context makes it easy for participants to engage their mindreading abilities. In two pre-registered self

Benchmarking the pediatric quality of life (PedsQL) cancer module in a large Dutch national cohort of childhood cancer patients

BACKGROUND: Pediatric cancer diagnosis and treatment reduce Health-Related Quality of Life (HRQoL). The Pediatric Quality of Life (PedsQL) Cancer Module is the most commonly used cancer specific HRQoL instrument, but most studies included relatively small cohorts and no reference scores are available. The development of a PedsQL Cancer Module benchmark, based on a large population of pediatric can

Consumer-Led Screening for Atrial Fibrillation : Frontier Review of the AF-SCREEN International Collaboration

The technological evolution and widespread availability of wearables and handheld ECG devices capable of screening for atrial fibrillation (AF), and their promotion directly to consumers, has focused attention of health care professionals and patient organizations on consumer-led AF screening. In this Frontiers review, members of the AF-SCREEN International Collaboration provide a critical apprais

In vitro stability of free prostate-specific antigen (PSA) and prostate- specific antigen (PSA) complexed to α1-antichymotrypsin in blood samples

Objectives. To study the in vitro stability of free and complexed forms of prostate specific antigen (PSA) in blood samples in order to establish guidelines for specimen handling, in particular for the clinical utility of the analysis of percentage free PSA. Methods. Blood samples were collected and processed to generate serum, heparin plasma, and EDTA plasma. Three different two-site immunoassays

Laglotten i modern tid

Laglotten regleras i ärvdabalken (1958:637) 7 kap. 1 § och fungerar som ett arvsrättsligt skydd till förmån för bröstarvingar. Skyddet aktualiseras i de fall då en avliden valt att testamentera bort all kvarlåtenskap. Bröstarvingar har i dessa fall en lagstadgad rätt till hälften av den dödes arvslott. Laglottsregleringen infördes år 1857, men har som institut funnits betydligt längre inom svensThe statutory share of inheritance is regulated by the inheritance code (1958:637) 7 chap. 1 § and work as a protection for the forced heir to secure its right for inheritance. The protection is activated in those cases where a deceased person has chosen to not give any of the properties left to a forced heir. In these cases, the statutory share of inheritance gives the forced heir the right to a

Microbial characterization of fields planted with the perennial crop Kernza® (Thinopyrum intermedium) and the annual crop Spring barley (Hordeum vulgare)

The terrestrial ecosystem stores up to 2400Gt of carbon in the upper 1m of the soil profile. However, this carbon storage is not stable and is vulnerable to loss. Agricultural soils with continuous heavy management drive a release of this soil carbon to the atmosphere. Recently, the implementation of perennial crops has been suggested as a method to facilitate a greater carbon sequestration. Howev

Energy Efficient Window Systems. Effects on Energy Use and Daylight in Buildings.

Popular Abstract in Swedish Denna avhandling handlar om energieffektiva fönstersystem i svenska byggnader. Simuleringar av energianvändningen har gjorts för både småhus och kontor för att bedöma effekterna av olika fönsterval på energibehov och inneklimat. Två års mätningar av energianvändning och innetemperaturer för ett energisnålt radhus har utvärderats. Två beteendestudier har även genomförts This thesis deals with energy-efficient windows in Swedish buildings. Parametric studies were performed in the dynamic energy simulation tool Derob-LTH in order to study the effects of window choices on energy use and indoor climate for both residential and office buildings. A steady-state program was used to evaluate two years of measurements of energy use and indoor temperatures of an energy-eff

Urodynamic effects of the K+ channel (KCNQ) opener retigabine in freely moving, conscious rats.

Purpose: Retigabine is a novel anticonvulsant drug that not only augments gamma-aminobutyric acid mechanisms, but also opens voltage gated K+ channels (KCNQ). In this study we investigated the effects of retigabine on detrusor activity in rats. Materials and Methods: To conscious, female Sprague-Dawley rats undergoing continuous cystometry retigabine was given intravenously (0.5, 1 and 5 mg/kg(-1)

Genomics and Evolution Studies of Dekkera bruxellensis, a Wine-Spoilage Yeast

Yeasts are unicellular fungi exhibiting a huge diversity of life styles and physiologies and their evolutionary span exceeds the one between mammals and unchordates. The recent advances in genome sequencing and comparative genomics accelerated genomic, evolutionary and physiological studies of yeasts, making them a very promising model to study eukaryotic cell, and also deepened our understanding

Risk of familial classical Hodgkin lymphoma by relationship, histology, age, and sex: A joint study from five Nordic countries.

The rarity of familial Hodgkin lymphoma (HL) has hampered detailed analyses of familial clustering. We aimed to provide the familial risk of HL by relationship, histology, age at diagnosis and sex. A cohort of 57,475 first-degree relatives of 13,922 HL patients, diagnosed between 1955 and 2009, in five European countries was followed for HL incidence. Standardized incidence ratios (SIRs) were calc