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The National Early Warning Score (NEWS) - Testing and evaluation in a Swedish setting

BackgroundDeviating vital signs have been known to precede Serious Adverse Events (SAEs) like In-Hospital Cardiac Arrest (IHCA), unplanned Intensive Care Unit (ICU) admission or unexpected death for more than a decade but still the recognition of these deteriorating patients is poor.The British National Early Warning Score (NEWS) is a ‘‘track and trigger’’ scale designed to assess in-hospital patiBackgroundDeviating vital signs have been known to precede Serious Adverse Events (SAEs) like In-Hospital Cardiac Arrest (IHCA), unplanned Intensive Care Unit (ICU) admission or unexpected death for more than a decade but still the recognition of these deteriorating patients is poor.The British National Early Warning Score (NEWS) is a ‘‘track and trigger’’ scale designed to assess in-hospital pati

No title

The current procedure of doctoral itinerary does not leave many choices to the doctoral supervisor: Once admitted, the doctoral student is required to defend three reports that are not graded in any way, and the commission can only offer some recommendations. The PhD supervisor cannot reject the report before supporting it. Everything is more a formality. Understanding this, many PhD students do n

Suicide as an incident of severe patient harm : A retrospective cohort study of investigations after suicide in Swedish healthcare in a 13-year perspective

Objectives To explore how mandatory reporting to the supervisory authority of suicides among recipients of healthcare services has influenced associated investigations conducted by the healthcare services, the lessons obtained and whether any suicide-prevention-related improvements in terms of patient safety had followed. Design and settings Retrospective study of reports from Swedish primary and

Area and reconfiguration time minimization of the communication network in regular 2D reconfigurable architectures

n this paper, we introduce a constraint programming-based approach for the optimization of area and of reconfiguration time for communication networks for a class of regular 2D reconfigurable processor array architectures. For a given set of different algorithms the execution of which is supposed to be switched upon request at run-time, we provide static solutions for the optimal routing of data b

How are children's best interests expressed during their hospital visit?-An observational study

Aims and objectives: To describe ways in which children's best interests were observed to be expressed in paediatric settings during their hospital visit.Background: The best interests of the child are embodied in national and international legal systems, although the definition remains problematic. The child's limited autonomy mandates duty bearers to have both a child perspective and the child's

Computational Fluid Dynamics Support for Fontan Planning in Minutes, Not Hours : The Next Step in Clinical Pre-Interventional Simulations

Computational fluid dynamics (CFD) modeling may aid in planning of invasive interventions in Fontan patients. Clinical application of current CFD techniques is however limited by complexity and long computation times. Therefore, we validated a "lean" CFD method to magnetic resonance imaging (MRI) and an "established" CFD method, ultimately aiming to reduce complexity to enable predictive CFD durin

On the sign recovery by least absolute shrinkage and selection operator, thresholded least absolute shrinkage and selection operator, and thresholded basis pursuit denoising

Basis pursuit (BP), basis pursuit deNoising (BPDN), and least absolute shrinkage and selection operator (LASSO) are popular methods for identifying important predictors in the high-dimensional linear regression model (Formula presented.). By definition, when (Formula presented.), BP uniquely recovers (Formula presented.) when (Formula presented.) and (Formula presented.) implies (Formula presented

Quality of life in patients with advanced epithelial ovarian cancer (EOC) randomized to maintenance pazopanib or placebo after first-line chemotherapy in the AGO-OVAR 16 trial. Measuring what matters-patient-centered end points in trials of maintenance therapy

Background: Health-related quality of life (HRQoL) was a secondary end point in AGO-OVAR 16, which randomized 940 patients with EOC after first-line chemotherapy to maintenance pazopanib (PZ) or placebo (P). Additional post hoc analyses were carried out to investigate additional patient-centered end points. Patients and methods: HRQoL was measured with EORTC-QLQ-C30, QLQ-OV28 and EQ-5D-3L. Pre-spe

In ovo yolk carotenoid and testosterone levels interactively influence female transfer of yolk antioxidants to her eggs

Mothers can influence prenatal conditions by varying the amount of nutrients, hormones or antioxidants they provide to their developing young. Some of these substances even affect the transfer of these compounds in the next generation, but it is less clear how different maternally transmitted compounds interact with each other to shape reproductive resource allocation in their offspring. Here, we

Effect of Piston Geometry on Stratification Formation in the Transition from HCCI to PPC

Partially premixed combustion (PPC) is an advanced combustion strategy that has been proposed to provide higher efficiency and lower emissions than conventional compression ignition, as well as greater controllability than homogeneous charge compression ignition (HCCI). Stratification of the fuel-air mixture is the key to achieving these benefits. The injection strategy, injector-piston geometry d

Relative paleointensity (RPI) in the latest Pleistocene (10–45 ka) and implications for deglacial atmospheric radiocarbon

We report magnetic properties and relative paleointensity (RPI) proxies from a suite of 10 conventional piston cores and Kasten cores from the SW Iberian Margin collected during cruise JC089 of the RSS James Cook in August 2013. Mean sedimentation rates are in the 10–20 cm/kyr range. Age models were acquired by correlation of Ca/Ti and Zr/Sr XRF core-scanning data to L* reflectance from the Cariac

Fracture Analysis of Orthotropic Beams : Linear Elastic and Non-Linear Methods

The use of timber as a construction material demands continuous improvements of our knowledge about the material and computational techniques for structural analysis and design.In this report the fracture properties of wood are studied and implemented into numerical crack propagation models. The numerical algorithms are utilized for computing the development of cracks in structural elements. Six t

Short- and long-term direct and indirect costs of illness after ostomy creation – a Swedish nationwide registry study

Background: Despite advance in care of people with an ostomy, related complications remain prevalent. The objective of this study was to examine short- and long-term healthcare resource utilization and associated costs after ostomy creation. Methods: This observational study was based on retrospectively collected data from national and regional Swedish registries. The population consisted of peopl

The impact of indigenous culture and business group affiliation on corporate governance of African firms

Research Question/Issue: This is a study of the relationship between business group ownership and constituent firms' adoption of Anglo-American shareholder value governance in African firms at the undertaking of an initial public offering (IPO). Research Findings/Insights: We find business group ownership to be associated with lower Anglo-American corporate governance adoption by constituent firms

Effect of a Smoking and Alcohol Cessation Intervention Initiated Shortly Before Radical Cystectomy—the STOP-OP Study : A Randomised Clinical Trial

Background: Evidence concerning the reduction of postoperative complications due to smoking and alcohol drinking in patients undergoing radical cystectomy is incomplete. Objective: To evaluate the efficacy of a 6-wk smoking and/or alcohol cessation intervention, initiated shortly before surgery and continued until 4 wk after, in reducing complications. Design, setting, and participants: Between 20

Transient birefringence and dichroism in ZnO studied with fs-time-resolved spectroscopic ellipsometry

The full transient dielectric-function (DF) tensor of ZnO after UV-laser excitation in the spectral range 1.4-3.6 eV is obtained by measuring an m-plane-oriented ZnO thin film with femtosecond (fs)-time-resolved spectroscopic ellipsometry. From the merits of the method, we can distinguish between changes in the real and the imaginary part of the DF as well as changes in birefringence and dichroism

Galectin-8N-Selective 4-Halophenylphthalazinone-Galactals Double π-Stack in a Unique Pocket

Galectin-8 contains two different carbohydrate recognition domains (CRDs). Selective inhibitors for at least one CRD are desirable for galectin-8 biology studies and potentially for pharmacological purposes. Structure-guided design led to the discovery of potent and selective glycomimetic-heterocycle hybrid ligands, with a 4-(p-bromophenyl)phthalazinone derivative displaying a 34 μM Kd for galecti

E-handelns effekt på inflationen - En paneldatastudie om den ökande e-handelns konsekvenser

Denna uppsats har syftet att analysera huruvida den ökande e-handeln pressar inflationen nedåt. Vi har behandlat och undersökt varierande teorier gällande faktorer som berörs av den ökande e-handeln, främst hur den väntas påverka prissättning och produktivitet genom ökad konkurrens från tre olika nivåer: producent-, konsument- och marknadsnivå. Data har sammanställts till paneldata för 30 europeisThis paper has the purpose of analyzing whether the growing e-commerce is pushing down inflation. We have dealt with theories concerning how e-commerce might affect price setting and increase competition on consumer-, producer-, and market level. Data concerning 30 European countries during a time period between 2002-2014 was set into a panel data and analyzed in an econometric framework. Our resu

Jämförelsestudie av riskbedömningar avseende vägtransport av farligt gods

Farligt gods definieras som ett ämne eller föremål som på grund av dess beskaffenheter kan orsaka skada på person, egendom och miljö, exempelvis bensin, gasol och svavelsyra. Farligt gods transporteras på vägar genom hela landet för att möjliggöra industriprocesser eller andra samhällsnyttiga funktioner. För att garantera att bebyggelse intill dessa vägar inte är utsatta för oacceptabla risker genRisk assessment regarding transportation of hazardous material is a central decision support in urban planning close transportation routes for hazardous material in Sweden. Risk assessment regarding transportation of hazardous is also uncertain and can give various results. In order to highlight this a comparative study is made to describe the differences in risk assessments both regarding impleme