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Attending physicians believe that hospitalized patients are treated at the appropriate level of care : A qualitative study

The purpose of this paper is to investigate the appropriateness of hospitalized patients’ level of care as assessed by their treating physicians. The study was conducted as a qualitative study, based on a questionnaire. The study suggests that physicians generally believe that patients who occupy in-hospital beds are cared for at the appropriate level of care. It is worth to note that a relatively

Cell-permeable succinate prodrugs bypass mitochondrial complex i deficiency

Mitochondrial complex I (CI) deficiency is the most prevalent defect in the respiratory chain in paediatric mitochondrial disease. This heterogeneous group of diseases includes serious or fatal neurological presentations such as Leigh syndrome and there are very limited evidence-based treatment options available. Here we describe that cell membrane-permeable prodrugs of the complex II substrate su

The unified extensional versioning model

Versioning of components in a system is a well-researched field where various adequate techniques have already been established. In this paper, we look at how versioning can be extended to cover also the structural aspects of a system. There exist two basic techniques for versioning - intentional and extensional - and we propose a unified extensional versioning model for versioning of both compone

Activity avoidance, perceived walking difficulties, and use of mobility devices in people with Parkinson's disease

Background: Parkinson's disease (PD) is a chronic progressive neurodegenerative disease that results in functional loss and disability. People with PD have an increased risk of falling, and most of their falls occur while walking. As yet, there is limited knowledge concerning activity avoidance due to perceived risk of falling in people with PD. In order to quantitatively assess perceived walking

The occurrence of comorbidities with affective and anxiety disorders among older people with intellectual disability compared with the general population : A register study

Background: Little is known regarding the burden of comorbidities among older people with intellectual disability (ID) who have affective and anxiety disorders. Therefore, we aimed to investigate the occurrence and risk of psychiatric and somatic comorbidities with affective and/or anxiety disorders in older people with ID compared to the general population. Methods: This population study was base

Dataset of ptychographic X-ray computed tomography of inverse opal photonic crystals produced by atomic layer deposition

This data article describes the detailed parameters for synthesizing mullite inverse opal photonic crystals via Atomic Layer Deposition (ALD), as well as the detailed image analysis routine used to interpret the data obtained by the measurement of such photonic crystals, before and after the heat treatment, via Ptychographic X-ray Computed Tomography (PXCT). The data presented in this article are

A novel nutritional supplement containing amino acids and chromium decreases postprandial glucose response in a randomized, double-blind, placebo-controlled study

High postprandial blood glucose levels are associated with increased mortality, cardiovascular events and development of diabetes in the general population. Interventions targeting postprandial glucose have been shown to prevent both cardiovascular events and diabetes. This study evaluates the efficacy and safety of a novel nutritional supplement targeting postprandial glucose excursions in non-di

A Family of Laminin α2 Chain-Deficient Mouse Mutants : Advancing the Research on LAMA2-CMD

The research on laminin α2 chain-deficient congenital muscular dystrophy (LAMA2-CMD) advanced rapidly in the last few decades, largely due to availability of good mouse models for the disease and a strong interest in preclinical studies from scientists all over the world. These mouse models continue to provide a solid platform for understanding the LAMA2-CMD pathology. In addition, they enable res

Gender, alexithymia and physical inactivity associated with abdominal obesity in type 1 diabetes mellitus: a cross sectional study at a secondary care hospital diabetes clinic

Background Obesity is linked to cardiovascular diseases and increasingly common in type 1 diabetes mellitus (T1DM) since the introduction of intensified insulin therapy. Our main aim was to explore associations between obesity and depression, anxiety, alexithymia and self-image measures and to control for lifestyle variables in a sample of persons with T1DM. Secondary aims were to explore associat

Pulmonell hypertension vanligt vid kronisk lungsjukdom

In 2015 the European Society of Cardiology and European Respiratory Society published new guidelines on the diagnosis and treatment of pulmonary hypertension (PH). PH due to lung diseases and/ or hypoxia was classified as a separate entity. PH is common in lung diseases, but seldom severe. Nevertheless, the presence of PH in a patient with lung disease is associated with worse outcome. If there is

An investigation of how the Emergency Team within UNFPA could achieve a more effective balancing of supply and demand

Bakgrund: Emergency Teamet skickar ut ERH-Kits då en efterfrågan från kunden uppstår, exempelvis efter en katastrofsituation. Emergency Teamet har blivit kritiserade för att inte ha svarat tillräckligt snabbt på efterfrågan och därför har Executive Director för UNFPA gett nya direktiv för att UNFPA ska svara snabbare och skapa bättre förutsättningar för att leverera snabbt i katastrofsituationer. Background: The Emergency Team within UNFPA operates when crisis strikes by distributing ERH-Kits to people in need. The Emergency Team has in the past been criticized of not responding rapidly enough to requests for ERH-Kits and the Executive Director of UNFPA has given new directives that UNFPA needs to become more responsive in its activities and create better prerequisites to deliver fast in e

GIS inom räddningstjänstens brandförebyggande arbete - En studie om tillämpningar i fem räddningstjänstförbund

Swedish fire and rescue services are in a transformation that shifts towards an increased focus on preventive actions as well as more strategic oriented activities within the organizations. To support and develop such types of activities, Geographical Information System (GIS) could be an effective tool to manage and analyze geographic data. This thesis aims to examine the prerequisites for develop

Assessment of Urban Sprawl in Mowe/Ibafo Axis of Ogun State using GIS Capabilities

Urban Sprawl is one of the challenges to urban development in many nations. Different aspects of the phenomenon have been researched with a view to providing solutions to myriad of ills attributed to it. For any meaningful intervention, however, assessment of development to ascertain sprawl is essential. Despite this, its quantification and monitoring in environment with paucity of data remains a

Psykisk ohälsa bland unga - en kvalitativ innehållsanalys av medias framställning

The aim of the study is to analyze how mental illness among young people is represented as a social problem in newspapers. A qualitative method has been utilized to analyze 63 different articles published within the period of 2019-01-01 to 2019-06-30 in three of Sweden’s largest newspapers. Additionally, the theoretical framework that has been applied is the theory of claims-making. Furthermore, i

Minimering av avfall i produktion av prefabricerade husmoduler

Leaving a sustainable society for our children is considered an arbitrary goal for the environmental work that is currently taking place in Sweden. Today, 140 million tonnes of non-hazardous waste is generated in Sweden, which is unsustainable. 31% of the non-hazardous waste is traced to the construction industry, the mining industry excluded. Today, the waste is an unused resource that is purchas

Evaluating the accuracy and precision of a two-compartment Kärger model using Monte Carlo simulations.

Specific parameters of the neuronal tissue microstructure, such as axonal diameters, membrane permeability and intracellular water fractions are assessable using diffusion MRI. These parameters are commonly estimated using analytical models, which may introduce bias in the estimated parameters due to the approximations made when deriving the models. As an alternative to using analytical models, a

Single nucleotide polymorphisms in the 20q13 amplicon genes in relation to breast cancer risk and clinical outcome

The 20q13 region is frequently amplified/overexpressed in breast tumours. However, the nature of this amplification/overexpression is unknown. Here, we investigated genetic variation in five 20q13 amplicon genes (MYBL2, AURKA, ZNF217, STK4 and PTPN1) and its impact on breast cancer (BC) susceptibility and clinical outcome. As a novel finding, four polymorphisms in STK4 (rs6017452, rs7271519) and A

Är hjärnhalvorna selektivt specialiserade på positiva och negativa emotioner? En visuell halvfältsstudie

Thirty right-handed participants were presented with emotional pictures either to the left or to the right visual field. The pictures were shown for a duration of 150 ms to make sure that they were exclusively presented to one hemisphere only. Eye movements were recorded with electroocularogram for each participant throughout the test. A total of 30 pictures were chosen on the basis of their valen

Experimental analysis of limitations in the strut-and-tie method

One of the overall main purposes for a structural engineer is to design structures and structural elements so that they meet society’s safety requirements, yet use as little material as possible. In order to do so, the designer has to understand and simplify a complex reality. The strut-and-tie method is such a simplification model which allows engineers to design reinforced concrete structures wh

Victim Blaming, Justified Risks, and Imperfect Victims

Victim blaming is a harmful but quite pervasive phenomenon occurring in contemporary societies. When people engage in victim blaming, they shift the burden of the harmful act from the perpetrators and place it upon the victims instead. This article explores how the discourse on moral responsibility can help make sense of victim blaming. The distinction between moral responsibility and blameworthin