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The effect of the EU and the Euro on European Countries’ Economic Growth

As trade wars commence and European integration deepens it becomes increasingly important to investigate the effects that such actions have on the economy. This thesis investigates the effect that the EU and Eurozone has on the economic growth of its member nations. The study utilizes an augmented Solow-model in a fixed effects framework to see the effect that the EU and Euro has had on economic g

Physics-Informed Reinforcement Learning Feasibility Study for Building Energy Optimization

Buildings worldwide account for 30% of energy consumption and Heating, Ventilation and Air Conditioning (HVAC) represent roughly 38% of a building’s consumption. Therefore, energy savings are crucial for sustainability. The complexity of buildings, with diverse physical domains and large-scale components, presents challenges to achieving energy-efficient operation. Implementing high-performance co

Three systems used for biocatalysis in organic solvents a comparative study

The activity and operational stability of horse liver alcohol dehydrogenase (HLADH) and αchymotrypsin were investigated in three systems commonly used for biocatalysis in organic solvents: 1. enzyme adsorbed on a solid support (celite) and added to the organic solvent (isooctane) 2. enzyme powder directly added to the organic solvent (isooctane). 3. enzyme dissolved in a microemulsion (AOT/isoocta

Improving serious illness communication : a qualitative study of clinical culture

OBJECTIVE: Communication about patients' values, goals, and prognosis in serious illness (serious illness communication) is a cornerstone of person-centered care yet difficult to implement in practice. As part of Serious Illness Care Program implementation in five health systems, we studied the clinical culture-related factors that supported or impeded improvement in serious illness conversations.

Antihypertensive efficacy of zofenopril compared with atenolol in patients with mild to moderate hypertension

Two first-line antihypertensive therapies for initiating treatment in hypertension were compared, the angiotensin-converting enzyme inhibitor (ACEI) zofenopril and the beta-blocker atenolol. The study was multi-centre and double-blind, and included 304 middle-aged to elderly patients with mild to moderate hypertension who were randomized to receive either zofenopril 30-60 mg once daily (od) or ate

Ultrastructural characterization of dissociated embryonic ventral mesencephalic tissue treated with neuroprotectants.

Poor survival and differentiation of grafted dopamine neurons limits the application of clinical transplantation in Parkinson’s disease. The survival of grafted dopamine neurons is only improved by a factor of 2–3 by adding neuroprotectants during tissue preparation. We used dye exclusion cell viability and electron microscopy to investigate the effects of the caspase inhibitor ac-YVAD-cmk and the

Important role of phosphodiesterase 3B for the stimulatory action of cAMP on pancreatic beta -cell exocytosis and release of insulin.

Cyclic AMP potentiates glucose-stimulated insulin release and mediates the stimulatory effects of hormones such as glucagon-like peptide 1 (GLP-1) on pancreatic b-cells. By inhibition of cAMP-degrading phosphodiesterase (PDE) and, in particular, selective inhibition of PDE3 activity, stimulatory effects on insulin secretion have been observed. Molecular and functional information on b-cell PDE3 is

Persistent pollutants in a salmon population (Salmo salar) of the southern Baltic Sea

Persistent pollutants in an Atlantic salmon (Salmo salar) population spawning in a river of southern Sweden were investigated. The population was characterized by a high growth rate. Some males reached 20-30 kg after 3 to 4 years in the sea. The fat content of migrating salmon varied by one order of magnitude and was the most significant correlate of pollutant concentrations. No relationships were

Choice-justifications after allocating resources in helping dilemmas

How do donors reason and justify their choices when faced with dilemmas in a charitable context? In two studies, Swedish students were confronted with helping dilemmas based on the identifiable victim effect, the proportion dominance effect and the ingroup effect. Each dilemma consisted of two comparable charity projects and participants were asked to choose one project over the other. They were t

Higher risk of revision for infection using systemic clindamycin prophylaxis than with cloxacillin : A report from the Swedish Knee Arthroplasty Register on 78,000 primary total knee arthroplasties for osteoarthritis

Background and purpose — Clindamycin has not been compared with other antibiotics for prophylaxis in arthroplasty. Since 2009, the Swedish Knee Arthroplasty Register (SKAR) has been collecting information on the prophylactic antibiotic regime used at every individual operation. In Sweden, when there is allergy to penicillin, clindamycin has been the recommended alternative. We examined whether the

Perspectives on Lattice Boltzmann Modeling of Transport Processes with Electrochemical Reactions in SOFCs

Lattice Boltzmann method (LBM) is alternative computational method to the traditional computational fluid dynamic (CFD) methods. LBM has the ability to with straightforward computational procedure to handle the detail activity at microscale well for simulation of different transport processes. In this study the focus is on the effects of electrochemical reactions and transport processes in an anod

Numerical and experimental study of the slot film cooling jet with various angles

Numerical simulations coupled with LDV experiments were carried out to investigate a slot jet issued into a cross flow, which is relevant in the film cooling of gas turbine combustors. The film cooling fluid injection from slots or holes into a cross-flow produces highly complicated flow fields. In this paper, the time-averaged Navier-Stokes equations were solved on a collocated body-fitted grid s

A literature review on fatigue among older people

Objective. The aim of the study was to survey existing research about fatigue among older people with chronic non-malignant pain. Method. A structured literature review was carried out using the Medline database. The terms ‘fatigue’ and ‘tiredness’ were used synonymously. These subject headings were combined with pain. A literature search was made in 2004 and included articles back to 1995. Resu

New investigations of the \'early streamer emission\' principle

An 'early streamer emission' (ESE) terminal, for lightning protection, stimulates a burst of streamers from its tip before producing streamers induced by the field of a downward leader, approaching from a thundercloud. It has been claimed to enhance the probability of attachment of a lightning channel to a protection system. Experiments are described in which the performance of a simulated 'early

Artificial neural networks improve and simplify intensive care mortality prognostication: a national cohort study of 217,289 first-time intensive care unit admissions

Purpose We investigated if early intensive care unit (ICU) scoring with the Simplified Acute Physiology Score (SAPS 3) could be improved using artificial neural networks (ANNs). Methods All first-time adult intensive care admissions in Sweden during 2009-2017 were included. A test set was set aside for validation. We trained ANNs with two hidden layers with random hyper-parameters and retained the

Small-Molecule Galectin Inhibitors - On Tweezers and Talosides

Abstract Work on the design, synthesis, and biological evaluation of galectin inhibitors is presented. The most significant results relate to the development of galactose-based arginine “tweezers” and taloside-based galectin inhibitors. The galectins are a β-galactoside binding protein family. They are involved in cancer and inflammation, thus comprising interesting pharmaceutical targets. Galact

A 2-year follow-up study of anxiety and depression in women referred for colposcopy after an abnormal cervical smear.

OBJECTIVES: The aim of this study was to determine if there were any long-lasting elevated anxiety levels in women attending colposcopy after an abnormal cervical smear. DESIGN: Prospective study. SETTING: Department of Obstetrics and Gynaecology, Malmö University Hospital, Sweden. POPULATION: One hundred consecutive women were invited to participate when referred for colposcopy. METHODS: Women in

Absence of adenosine A(1) receptors unmasks pulses of insulin release and prolongs those of glucagon and somatostatin.

AIMS: Extracellular ATP modulates pulsatile release of insulin, glucagon and somatostatin by activating P2Y(1) receptors. The present study examines if adenosine via A(1) receptors (A(1)R) interferes with pulsatile islet hormone release. MAIN METHODS: Pancreas was perfused in mice expressing or lacking the A(1) receptor and the hormones measured with radioimmunoassay. Cytoplasmic Ca(2+) was record