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The prognostic impact of t(12;21)(p13;q22) [ETV6/RUNX1 fusion] in paediatric acute lymphoblastic leukaemia (ALL) has been extensively debated, particularly with regard to the frequency of late relapses and appropriate treatment regimens. We have retrospectively collected 679 ALLs with known ETV6/RUNX1 status, as ascertained by fluorescence in situ hybridization or reverse-transcription polymerase

Our aim is to use clustering algorithms in order to compute support and resistance levels within an intra-day trading setting. To achieve this we use a tick data set from the EUR-USD exchange market during 2019 as a measure of market activity. Both the Gaussian Mixed Model (GMM) and an altered form of Kmeans clustering will be used as clustering methods where each method will be evaluated using a

Author: Ebba Eiroff Title: Students narratives of loneliness Supervisor: Kristina Göransson Assessor: Mats Hilte The aim for this qualitative study was to examine university students experiences of loneliness based on Erving Goffman’s dramaturgy theory, together with the conceptions of normality, shame and guilt. How students describe feelings of loneliness and how they relate their experiences t

There is a rising demand for decarbonizing the building sector since it significantly contributes to global carbon emissions. With a focus on the mechanical, electrical, and plumbing systems specifically, this master’s thesis explores the embodied carbon within these building service systems. Utilizing established life cycle assessment methodologies, the case study thoroughly examines the embodied

The purpose of this study was to analyze how parents of children with neuropsychiatric disorders experience their parenthood. More specifically the aim was to allow parents of children with the neuropsychiatric diagnosis ADHD to share their experiences of parenting related to a variety of themes. These themes, family situation, school, knowledge, positive experiences, problems and difficulties, he

The aim of this study is to examine the relationship between budget support and corruption. This is done by conducting a case study of political will to fight corruption of Tanzanian reformers, using Brinkerhoffs framework of political will. The study shows that the Tanzanian reformers have a weak political will to fight corruption, which impedes the results of the budget support. Also,budget supp

Domedagsklockan klämtar alltjämt ljudligt för planeten. Vi står inför flera globala, nationella och lokala miljöutmaningar som kan komma att påverka framtida generationer på ödesdigra sätt. Hur individer och organisationer arbetar med dessa frågor kan vara avgörande för samhällets framtida fortlevnad. Ekonomiskt stöd till en mångfald av externa projekt kan vara ett sätt att låta gräsrötter växa tiSociety is facing numerous environmental challenges today and tomorrow. Several global, national, and regional frameworks and instruments are in place to battle the storm. The Regional Council in Scania works with environmental issues through different programs and methods. Miljövårdsfonden is one of these methods, where financial support is allocated to various external projects to further a posi

Informal employment in the 21st century is increasingly prevalent across the world and becomes particularly insecure in the Global South. This thesis studies different aspects of the precarious nature of informal sector jobs in a specific district in India. The research is built upon the concept of precarity which refers to instability, vulnerability and the volatile essence of the informal labor

About 15-20% of all pregnancies end in miscarriage. The phenomenon is common throughout the population, but bereaved women and couples struggle nonetheless. Lang et al. (2011) have shown that a miscarriage can cause shock, grief and pain and lead women into questioning their reproductive abilities. Hiefner (2012) has argued that pregnancy loss is surrounded by a norm of silence, making it difficul

Currently, industries are actively pursuing heat decarbonization solutions, yet face challenges in identifying and understanding suitable options for their facilities. Thermal energy storage (TES), systems that capture and store renewable energy for prolonged periods to provide superheated steam, are presented as a promising but relatively recent solution for decarbonizing heat-intensive industrie

The Nagorno-Karabakh conflict is a protracted dispute between the states Armenia and Azerbaijan. This study develops a framework for how dependence on Russia affected the conflict outcome in 2020-2023. The framework explains the possible effects of an asymmetric relationship between the great power Russia and two weaker powers in Armenia and Azerbaijan while in a violent conflict. In the quantitat

Samhället idag kännetecknas av digital interaktion, där både privata såväl som yrkesmässiga kontakter sker via olika tekniska plattformar. Människor skrol-lar, kommunicerar och tar till sig information via mobiltelefoner eller datorer vilket har blivit det normala sättet att interagera i vardagen. Allt fler rättsområ-den har tagit digitaliseringen i beaktning, men det finns fortfarande rättsområ-dSociety today is characterized by digital interaction, with both private and pro-fessional contacts taking place through various technological platforms. Peo-ple browse, communicate and absorb information via mobile phones or com-puters, which has become the normal way of interacting in everyday life. More and more areas of law have taken digitalization into account, but there are still areas of l

BackgroundThere is a need for a measure that can be used across countries and cultures to advance cross-cultural research about internalizing mental health symptoms in children and adolescents. The Revised Children's Anxiety and Depression Scale (RCADS) is a potential candidate, but no study has examined whether its scales are measured similarly in youth populations from different countries.Method

In this paper, we investigate the social herding phenomenon known as informational cascades, in which sequential inter-agent communication might lead to epistemic failures at group level, despite availability of information that should be sufficient to track the truth. We model an example of a cascade, and check the correctness of the individual reasoning of each agent involved, using two alternat

During the last decades a striking decline has been observed for wild bees throughout central and north-western Europe, including Sweden. in an area of 64 km' in the parish of Stenbrohult, southern Smaland Andrena hattorfiana, Andrena humilis, Nomada armata and Panurgus hanksianus were studied (in Sweden red-listed as VU, EN, EN and VU). We present occurrence patterns in relation to habitat types

Background & Aims: Human milk is believed to contain biological factors involved in the regulation of newborn growth, including brain development. Recently, it has also been shown to contain the calcium-binding S100B protein, regarded as a neurotrophic factor. The present study investigates the concentrations of this protein in colostrum, human milk at different levels of maturation and in mil

Background: There have been reports both supporting and refuting an inverse relationship between hip fracture and hip osteoarthritis (OA). We explore this relationship using a case-control study design. Methods: Exclusion criteria were previous hip fracture (same side or contralateral side), age younger than 60 years, foreign nationality, pathological fracture, rheumatoid arthritis and cases were

The objective of the present experiments was to study mechanisms governing cerebrovascular responses during severe hypoglycemia, and in the posthypoglycemic recovery period. To that end, lightly anesthetized (70% N2O) and artificially ventilated rats were injected with insulin so as to abolish spontaneous EEG activity for 15 or 30 min ("coma"). In separate animals, recovery was induced by glucose

The long term effects of driving with an active accelerator pedal (AAP) on driver behaviour was studied by using an in car observation method. The AAP produced a counterforce in the accelerator pedal when the speed limit was reached, it could however be overridden by pressing the accelerator pedal harder. Twenty-eight drivers were studied when driving without the AAP and then when driving with the

We evaluated biotic and abiotic predictors of rest-phase hypothermia in wintering blue tits (Cyanistes caeruleus) and also assessed how food availability influences nightly thermoregulation. On any given night, captive blue tits (with unrestricted access to food) remained largely homeothermic, whereas free-ranging birds decreased their body temperature (T (b)) by about 5 degrees C. This was not an